Publications by authors named "Nick Bown"

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Mutations Are Associated with Resistance to Non-Genotoxic MDM2 Inhibition in Chronic Lymphocytic Leukemia.
Erhan Aptullahoglu, Jonathan P Wallis, Helen Marr, Scott Marshall, Nick Bown

Int J Mol Sci· July 2023

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Splicing Modulation Results in Aberrant Isoforms and Protein Products of p53 Pathway Genes and the Sensitization of B Cells to Non-Genotoxic MDM2 Inhibition.
Erhan Aptullahoglu, Carmela Ciardullo, Jonathan P Wallis, Helen Marr, Scott Marshall, Nick Bown

Int J Mol Sci· January 2023

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Loss of ALK hotspot mutations in relapsed neuroblastoma.
Lisa M Allinson, Aaron Potts, Angharad Goodman, Nick Bown, Matthew Bashton

Genes Chromosomes Cancer· December 2022

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Advanced molecular pathology for rare tumours: A national feasibility study and model for centralised medulloblastoma diagnostics.
Stephen Crosier, Debbie Hicks, Edward C Schwalbe, Daniel Williamson, Sarah Leigh Nicholson, Nick Bown

Neuropathol Appl Neurobiol· October 2021

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Frequency and Prognostic Impact of Amplifications and Mutations in the European Neuroblastoma Study Group (SIOPEN) High-Risk Neuroblastoma Trial (HR-NBL1).
Angela Bellini, Ulrike Pötschger, Virginie Bernard, Eve Lapouble, Sylvain Baulande, Nick Bown

J Clin Oncol· October 2021

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Epigenome-wide analysis reveals functional modulators of drug sensitivity and post-treatment survival in chronic lymphocytic leukaemia.
Timothy M Barrow, Sirintra Nakjang, Fadhel Lafta, Kateryna Bilotkach, Laura Woodhouse, Nick Bown

Br J Cancer· January 2021

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Age Dependency of the Prognostic Impact of Tumor Genomics in Localized Resectable -Nonamplified Neuroblastomas. Report From the SIOPEN Biology Group on the LNESG Trials and a COG Validation Group.
Inge M Ambros, Gian-Paolo Tonini, Ulrike Pötschger, Nicole Gross, Véronique Mosseri, Nick Bown

J Clin Oncol· November 2020

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Detection of Circulating and Disseminated Neuroblastoma Cells Using the ImageStream Flow Cytometer for Use as Predictive and Pharmacodynamic Biomarkers.
Swathi Merugu, Lindi Chen, Elizabeth Gavens, Hany Gabra, Mark Brougham, Nick Bown

Clin Cancer Res· January 2020

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Non-genotoxic MDM2 inhibition selectively induces a pro-apoptotic p53 gene signature in chronic lymphocytic leukemia cells.
Carmela Ciardullo, Erhan Aptullahoglu, Laura Woodhouse, Wei-Yu Lin, Jonathan P Wallis, Nick Bown

Haematologica· December 2019

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Characterization and drug sensitivity of a novel human ovarian clear cell carcinoma cell line genomically and phenotypically similar to the original tumor.
Miriam Franklin, Lucy Gentles, Elizabeth Matheson, Nick Bown, Paul Cross

Cancer Med· September 2018

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British Committee for Standards in Haematology guidelines for aplastic anemia: Single centre retrospective review finds no compelling evidence for the recommended higher platelet count threshold of 20 × 10 /L - RESPONSE to Yan et al.
Sally B Killick, Nick Bown, Jamie Cavenagh, Inderjeet Dokal, Theodora Foukaneli

Br J Haematol· July 2018

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Heterogeneous MYCN amplification in neuroblastoma: a SIOP Europe Neuroblastoma Study.
Ana P Berbegall, Dominik Bogen, Ulrike Pötschger, Klaus Beiske, Nick Bown

Br J Cancer· May 2018

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Identification of different ALK mutations in a pair of neuroblastoma cell lines established at diagnosis and relapse.
Lindi Chen, Angharad Humphreys, Lisa Turnbull, Angela Bellini, Gudrun Schleiermacher, Nick Bown

Oncotarget· December 2016

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Factors associated with recurrence and survival length following relapse in patients with neuroblastoma.
Nermine O Basta, Gail C Halliday, Guy Makin, Jillian Birch, Richard Feltbower, Nick Bown

Br J Cancer· October 2016

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The effect of FLT3-ITD and NPM1 mutation on survival in intensively treated elderly patients with cytogenetically normal acute myeloid leukemia - Response to Rashidi et al.
Andrew Kenneth McGregor, Deborah Moulton, Nick Bown, Gavin Cuthbert, David Bourn

Leuk Lymphoma· August 2016

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Incidence and outcomes for adults diagnosed with acute myeloid leukemia in the north of England: a real world study.
Andrew Kenneth McGregor, Deborah Moulton, Nick Bown, Gavin Cuthbert, David Bourn

Leuk Lymphoma· July 2016

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Guidelines for cytogenetic investigations in tumours.
Rosalind J Hastings, Nick Bown, Maria G Tibiletti, Maria Debiec-Rychter, Roberta Vanni

Eur J Hum Genet· January 2016

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Guidelines for the diagnosis and management of adult aplastic anaemia.
Sally B Killick, Nick Bown, Jamie Cavenagh, Inderjeet Dokal, Theodora Foukaneli

Br J Haematol· January 2016

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Methyl-CpG-binding domain sequencing reveals a prognostic methylation signature in neuroblastoma.
Anneleen Decock, Maté Ongenaert, Robrecht Cannoodt, Kimberly Verniers, Bram De Wilde, Nick Bown

Oncotarget· January 2016

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Exome Sequencing of an Adult Pituitary Atypical Teratoid Rhabdoid Tumor.
Swethajit Biswas, Madeleine Wood, Abhijit Joshi, Nick Bown, Lisa Strain

Front Oncol· November 2015

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Rhabdoid Variant of Myoepithelial Carcinoma, with EWSR1 Rearrangement: Expanding the Spectrum of EWSR1-Rearranged Myoepithelial Tumors.
Khin Thway, Nick Bown, Aisha Miah, Rob Turner, Cyril Fisher

Head Neck Pathol· June 2015

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Cutaneous B-lymphoblastic lymphoma with IL3/IgH translocation presenting with hypereosinophilia and acute endocarditis.
Simon Bomken, Shaun Haigh, Nick Bown, Peter Carey, Katrina Wood

Pediatr Blood Cancer· June 2015

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Response to the letter to the editor: 1q gain is a frequent finding in preoperatively treated Wilms tumors, but of limited prognostic value for risk satisfaction in the SIOP2009/Gesellschaft für Pädiatrische Onkologie und Hämatologie (GPOH) trial.
Kathy Pritchard-Jones, Richard Williams, Heidi Segers, Marry van den Heuvel-Eibrink, Rob Pieters, Nick Bown

Genes Chromosomes Cancer· June 2015

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Constitutional and somatic rearrangement of chromosome 21 in acute lymphoblastic leukaemia.
Yilong Li, Claire Schwab, Sarra Ryan, Elli Papaemmanuil, Hazel M Robinson, Nick Bown

Nature· April 2014

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Pediatric chronic myeloid leukemia with B-cell lymphoid blast crisis at presentation.
Prasad Iyer, Peter Carey, Nick Bown, Sujith Samarasinghe

Blood Res· June 2013

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