Publications by authors named "Elizabeth Matheson"

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Evaluating the potential of kinase inhibitors to suppress DNA repair and sensitise ovarian cancer cells to PARP inhibitors.
Asima Mukhopadhyay, Yvette Drew, Elizabeth Matheson, Mo Salehan, Lucy Gentles

Biochem Pharmacol· September 2019

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Glucocorticoids and selumetinib are highly synergistic in RAS pathway-mutated childhood acute lymphoblastic leukemia through upregulation of BIM.
Elizabeth C Matheson, Huw Thomas, Marian Case, Helen Blair, Rosanna K Jackson

Haematologica· September 2019

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Exploring the Frequency of Homologous Recombination DNA Repair Dysfunction in Multiple Cancer Types.
Lucy Gentles, Bojidar Goranov, Elizabeth Matheson, Ashleigh Herriott, Angelika Kaufmann

Cancers (Basel)· March 2019

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Characterization and drug sensitivity of a novel human ovarian clear cell carcinoma cell line genomically and phenotypically similar to the original tumor.
Miriam Franklin, Lucy Gentles, Elizabeth Matheson, Nick Bown, Paul Cross

Cancer Med· September 2018

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CREBBP knockdown enhances RAS/RAF/MEK/ERK signaling in Ras pathway mutated acute lymphoblastic leukemia but does not modulate chemotherapeutic response.
Zach A Dixon, Lindsay Nicholson, Martin Zeppetzauer, Elizabeth Matheson, Paul Sinclair

Haematologica· April 2017

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Integration of genetic and clinical risk factors improves prognostication in relapsed childhood B-cell precursor acute lymphoblastic leukemia.
Julie A E Irving, Amir Enshaei, Catriona A Parker, Rosemary Sutton, Roland P Kuiper, Elizabeth Matheson

Blood· August 2016

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Quantitative proteomic analysis reveals maturation as a mechanism underlying glucocorticoid resistance in B lineage ALL and re-sensitization by JNK inhibition.
Lindsay Nicholson, Caroline A Evans, Elizabeth Matheson, Lynne Minto, Christopher Keilty

Br J Haematol· November 2015

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Ras pathway mutations are prevalent in relapsed childhood acute lymphoblastic leukemia and confer sensitivity to MEK inhibition.
Julie Irving, Elizabeth Matheson, Lynne Minto, Helen Blair, Marian Case

Blood· November 2014

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Casitas B lymphoma mutations in childhood acute lymphoblastic leukemia.
Lindsay Nicholson, Thomas Knight, Elizabeth Matheson, Lynne Minto, Marian Case

Genes Chromosomes Cancer· March 2012

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Mismatch repair and the downstream target genes, PAX5 and Ikaros, in childhood acute lymphoblastic leukemia.
Andrew Best, Elizabeth Matheson, Lynne Minto, Andrew G Hall, Julie A E Irving

Leuk Res· August 2010

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The relationship between IQ, memory, executive function, and processing speed in recent-onset psychosis: 1-year stability and clinical outcome.
Verity C Leeson, Thomas R E Barnes, Masuma Harrison, Elizabeth Matheson, Isobel Harrison

Schizophr Bull· March 2010

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Alternative splicing of hMLH1 in childhood acute lymphoblastic leukaemia and characterisation of the variably expressed Delta9/10 isoform as a dominant negative species.
Amy Peasland, Elizabeth Matheson, Andy Hall, Julie Irving

Leuk Res· March 2010

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Discrimination learning, reversal, and set-shifting in first-episode schizophrenia: stability over six years and specific associations with medication type and disorganization syndrome.
Verity C Leeson, Trevor W Robbins, Elizabeth Matheson, Samuel B Hutton, María A Ron

Biol Psychiatry· September 2009

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Variable breakpoints target PAX5 in patients with dicentric chromosomes: a model for the basis of unbalanced translocations in cancer.
Qian An, Sarah L Wright, Zoë J Konn, Elizabeth Matheson, Lynne Minto

Proc Natl Acad Sci U S A· November 2008

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Mutation of genes affecting the RAS pathway is common in childhood acute lymphoblastic leukemia.
Marian Case, Elizabeth Matheson, Lynne Minto, Rosline Hassan, Christine J Harrison

Cancer Res· August 2008

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DHFR and MSH3 co-amplification in childhood acute lymphoblastic leukaemia, in vitro and in vivo.
Elizabeth C Matheson, Linda A Hogarth, Marian C Case, Julie A E Irving, Andrew G Hall

Carcinogenesis· June 2007

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Glucocorticoid resistance in two key models of acute lymphoblastic leukemia occurs at the level of the glucocorticoid receptor.
Stefan Schmidt, Julie A E Irving, Lynne Minto, Elizabeth Matheson, Lindsay Nicholson

FASEB J· December 2006

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Detecting mismatch repair defects in myeloma.
Mark Velangi, Elizabeth Matheson, Andrew Hall, Julie Irving

Methods Mol Med· July 2005

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DNA mismatch repair pathway defects in the pathogenesis and evolution of myeloma.
Mark R Velangi, Elizabeth C Matheson, Gareth J Morgan, Graham H Jackson, Penelope R Taylor

Carcinogenesis· October 2004

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Mismatch repair activity in mammalian mitochondria.
Penelope A Mason, Elizabeth C Matheson, Andrew G Hall, Robert N Lightowlers

Nucleic Acids Res· February 2003

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Interactions of the DNA mismatch repair proteins MLH1 and MSH2 with c-MYC and MAX.
Mary Mac Partlin, Elizabeth Homer, Helen Robinson, Carol J McCormick, Dorothy H Crouch, Elizabeth C Matheson

Oncogene· February 2003

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Assessment of mismatch repair function in leukaemic cell lines and blasts from children with acute lymphoblastic leukaemia.
Elizabeth C Matheson, Andrew G Hall

Carcinogenesis· January 2003

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The effect of thiopurine methyltransferase expression on sensitivity to thiopurine drugs.
Sally A Coulthard, Linda A Hogarth, Margaret Little, Elizabeth C Matheson, Christopher P F Redfern

Mol Pharmacol· July 2002

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