Publications by authors named "Helen Robinson"

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Discovery of ART5537: A Potent and Selective Small-Molecule Probe for EXO1.
Sam E Mann, Owen A Davis, Jörg Bomke, Irina Cornaciu, Elias Elinati, Helen M R Robinson

J Med Chem· December 2025

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Mechanistic insights into the monotherapy and combination potential of FEN1 inhibition in cancer therapy.
Eeson Rajendra, Claudio A Lademann, Bethany Mason, Balca R Mardin, Lucy Armstrong, Helen M R Robinson

Nucleic Acids Res· November 2025

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Fragment-Based Discovery and Structure-Led Optimization of MSC778, the First Potent, Selective, and Orally Bioavailable FEN1 Inhibitor.
Sam E Mann, Julien Lefranc, Omar Alkhatib, Roch Boivin, Jörg Bomke, Helen M R Robinson

J Med Chem· October 2025

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Discovery of ART0380, a Potent and Selective ATR Kinase Inhibitor Undergoing Phase 2 Clinical Studies for the Treatment of Advanced or Metastatic Solid Cancers.
Christopher L Carroll, Michael G Johnson, Yanbing Ding, Zhijun Kang, R S K Vijayan, Helen M R Robinson

J Med Chem· December 2024

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Assessment of DNA Double Strand Break Repair Activity Using High-throughput and Quantitative Luminescence-based Reporter Assays.
Diego Grande, Eeson Rajendra, Bethany Mason, Alessandro Galbiati, Simon J Boulton, Helen M R Robinson

J Vis Exp· June 2024

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Ataxia-Telangiectasia Mutated Loss-of-Function Displays Variant and Tissue-Specific Differences across Tumor Types.
Patrick G Pilié, Virginia Giuliani, Wei-Lien Wang, Daniel J McGrail, Christopher A Bristow, Helen M R Robinson

Clin Cancer Res· May 2024

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Quantitative, titratable and high-throughput reporter assays to measure DNA double strand break repair activity in cells.
Eeson Rajendra, Diego Grande, Bethany Mason, Daniela Di Marcantonio, Lucy Armstrong, Helen M R Robinson

Nucleic Acids Res· February 2024

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Targeting ATR in Cancer Medicine.
Carolina Salguero, Christian Valladolid, Helen M R Robinson, Graeme C M Smith, Timothy A Yap

Cancer Treat Res· November 2023

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Small-Molecule Polθ Inhibitors Provide Safe and Effective Tumor Radiosensitization in Preclinical Models.
Gonzalo Rodriguez-Berriguete, Marco Ranzani, Remko Prevo, Rathi Puliyadi, Nicole Machado, Helen M R Robinson

Clin Cancer Res· April 2023

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Correction to "Discovery, Characterization, and Structure-Based Optimization of Small-Molecule In Vitro and In Vivo Probes for Human DNA Polymerase Theta".
Martin L Stockley, Giovanni Benedetti, Peter Blencowe, Simon J Boulton, Susan M Boyd, Helen M R Robinson

J Med Chem· February 2023

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POLQ seals post-replicative ssDNA gaps to maintain genome stability in BRCA-deficient cancer cells.
Ondrej Belan, Marie Sebald, Marek Adamowicz, Roopesh Anand, Aleksandra Vancevska, Helen M R Robinson

Mol Cell· December 2022

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Discovery, Characterization, and Structure-Based Optimization of Small-Molecule In Vitro and In Vivo Probes for Human DNA Polymerase Theta.
Martin L Stockley, Amanda Ferdinand, Giovanni Benedetti, Peter Blencowe, Susan M Boyd, Helen M R Robinson

J Med Chem· October 2022

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The Real-Life Outcome of VACOped Boot in the Management of Diabetic Foot Ulcers.
Wee Teck Lim, Helen Robinson, Edward Jude, Satyan Rajbhandari

Int J Low Extrem Wounds· September 2022

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Global Globin Network Consensus Paper: Classification and Stratified Roadmaps for Improved Thalassaemia Care and Prevention in 32 Countries.
Bin Hashim Halim-Fikri, Carsten W Lederer, Atif Amin Baig, Siti Nor Assyuhada Mat-Ghani, Sharifah-Nany Rahayu-Karmilla Syed-Hassan, Helen Robinson

J Pers Med· March 2022

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The effect of cannabis policies on treatment outcomes for cannabis use among U.S. adults.
Jessica L Bourdon, Meredith W Francis, Lena Jia, Chenxue Liang, Helen I Robinson

J Subst Abuse Treat· December 2021

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Predictive validity of a qualitative and quantitative Prechtl's General Movements Assessment at term age: Comparison between preterm infants and term infants with HIE.
Helen Robinson, Denise Hart, Brigitte Vollmer

Early Hum Dev· October 2021

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Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance.
Diana Zatreanu, Helen M R Robinson, Omar Alkhatib, Marie Boursier, Harry Finch

Nat Commun· June 2021

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"Can I Live": Black American Adolescent Boys' Reports of Police Abuse and the Role of Religiosity on Mental Health.
Ashley N Jackson, Sheretta T Butler-Barnes, Jewell D Stafford, Helen Robinson, Phylicia C Allen

Int J Environ Res Public Health· June 2020

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Fluoride occurrence in the lower East African Rift System, Southern Malawi.
Marc J Addison, Michael O Rivett, Helen Robinson, Aimee Fraser, Alexandra M Miller

Sci Total Environ· April 2020

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SOMANZ position paper on the management of nausea and vomiting in pregnancy and hyperemesis gravidarum.
Sandra A Lowe, Georgina Armstrong, Amanda Beech, Lucy Bowyer, Luke Grzeskowiak, Helen Robinson

Aust N Z J Obstet Gynaecol· February 2020

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Ketonuria Is Associated with Changes to the Abundance of in the Gut Microbiota of Overweight and Obese Women at 16 Weeks Gestation: A Cross-Sectional Observational Study.
Helen Robinson, Helen Barrett, Luisa Gomez-Arango, H David McIntyre, Leonie Callaway

Nutrients· August 2019

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A oocyte model system to study action potentials.
Aaron Corbin-Leftwich, Hannah E Small, Helen H Robinson, Carlos A Villalba-Galea, Linda M Boland

J Gen Physiol· November 2018

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Prevalence of maternal urinary ketones in pregnancy in overweight and obese women.
Helen L Robinson, Helen L Barrett, Katie Foxcroft, Leonie K Callaway, Marloes Dekker Nitert

Obstet Med· June 2018

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SOMANZ guidelines for the investigation and management sepsis in pregnancy.
Lucy Bowyer, Helen L Robinson, Helen Barrett, Timothy M Crozier, Michelle Giles

Aust N Z J Obstet Gynaecol· October 2017

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Increasing the involvement of diverse populations in genomics-based health care-lessons from haemoglobinopathies.
Helen M Robinson

J Community Genet· October 2017

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