Publications by authors named "Nick Edwards"

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Diagnosis of Plasmodium falciparum malaria at very low parasitaemias using a commercially available LAMP assay and RDT.
Ruth O Payne, Nick J Edwards, Yrene Themistocleous, Sarah E Silk, Jordan R Barrett

Trans R Soc Trop Med Hyg· October 2025

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Development of clinical immunity to Plasmodium vivax following repeat controlled human malaria infection.
Mimi M Hou, Adam C Harding, Natalie M Barber, Prasun Kundu, Florian A Bach, Nick J Edwards

Nat Commun· September 2025

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Plasmodium falciparum infection induces T cell tolerance that is associated with decreased disease severity upon re-infection.
Diana Muñoz Sandoval, Florian A Bach, Alasdair Ivens, Adam C Harding, Natasha L Smith, Nick J Edwards

J Exp Med· July 2025

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R21 in Matrix-M adjuvant in UK malaria-naive adult men and non-pregnant women aged 18-45 years: an open-label, partially blinded, phase 1-2a controlled human malaria infection study.
Navin Venkatraman, Daniel Silman, Duncan Bellamy, Lisa Stockdale, Georgina Bowyer, Nick J Edwards

Lancet Microbe· March 2025

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High-resolution African HLA resource uncovers HLA-DRB1 expression effects underlying vaccine response.
Alexander J Mentzer, Alexander T Dilthey, Martin Pollard, Deepti Gurdasani, Emre Karakoc, Nick Edwards

Nat Med· May 2024

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Analyses of human vaccine-specific circulating and bone marrow-resident B cell populations reveal benefit of delayed vaccine booster dosing with blood-stage malaria antigens.
Jordan R Barrett, Sarah E Silk, Catherine G Mkindi, Karolina M Kwiatkowska, Mimi M Hou, Nick J Edwards

Front Immunol· February 2024

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Acute kidney injury in dogs following ingestion of cream of tartar and tamarinds and the connection to tartaric acid as the proposed toxic principle in grapes and raisins.
Nicola Bates, Zoe Tizzard, Nick Edwards

J Vet Emerg Crit Care (San Antonio)· November 2023

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A systematic analysis of the human immune response to Plasmodium vivax.
Florian A Bach, Diana Muñoz Sandoval, Michalina Mazurczyk, Yrene Themistocleous, Thomas A Rawlinson, Nick J Edwards

J Clin Invest· October 2023

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Vaccination with Duffy-binding protein inhibits parasite growth during controlled human malaria infection.
Mimi M Hou, Jordan R Barrett, Yrene Themistocleous, Thomas A Rawlinson, Ababacar Diouf, Nick J Edwards

Sci Transl Med· July 2023

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Persistence of the immune response after two doses of ChAdOx1 nCov-19 (AZD1222): 1 year of follow-up of two randomized controlled trials.
Merryn Voysey, Amy Flaxman, Jeremy Aboagye, Parvinder K Aley, Sandra Belij-Rammerstorfer, Nick J Edwards

Clin Exp Immunol· March 2023

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Human leukocyte antigen alleles associate with COVID-19 vaccine immunogenicity and risk of breakthrough infection.
Alexander J Mentzer, Daniel O'Connor, Sagida Bibi, Irina Chelysheva, Elizabeth A Clutterbuck, Nick J Edwards

Nat Med· January 2023

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Repeat controlled human malaria infection of healthy UK adults with blood-stage : Safety and parasite growth dynamics.
Jo Salkeld, Yrene Themistocleous, Jordan R Barrett, Celia H Mitton, Thomas A Rawlinson, Nick J Edwards

Front Immunol· September 2022

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Impact of a blood-stage vaccine on malaria.
Mimi M Hou, Jordan R Barrett, Yrene Themistocleous, Thomas A Rawlinson, Ababacar Diouf, Nick J Edwards

medRxiv· May 2022

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Hops toxicosis in dogs.
Nicola Bates, Zoe Tizzard, Nick Edwards

J Vet Emerg Crit Care (San Antonio)· March 2022

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Safety and Immunogenicity of ChAd63/MVA Pfs25-IMX313 in a Phase I First-in-Human Trial.
Hans de Graaf, Ruth O Payne, Iona Taylor, Kazutoyo Miura, Carol A Long, Nick J Edwards

Front Immunol· December 2021

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Controlled human malaria infection with a clone of Plasmodium vivax with high-quality genome assembly.
Angela M Minassian, Yrene Themistocleous, Sarah E Silk, Jordan R Barrett, Alison Kemp, Nick J Edwards

JCI Insight· December 2021

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Author Correction: Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses.
Jordan R Barrett, Sandra Belij-Rammerstorfer, Christina Dold, Katie J Ewer, Pedro M Folegatti, Nick Edwards

Nat Med· June 2021

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Reduced blood-stage malaria growth and immune correlates in humans following RH5 vaccination.
Angela M Minassian, Sarah E Silk, Jordan R Barrett, Carolyn M Nielsen, Kazutoyo Miura, Nick J Edwards

Med· June 2021

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Mapping immune variation and gene switching in naive hosts infected with .
Kathryn Milne, Alasdair Ivens, Adam J Reid, Magda E Lotkowska, Aine O'Toole, Nick J Edwards

Elife· March 2021

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Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses.
Jordan R Barrett, Sandra Belij-Rammerstorfer, Christina Dold, Katie J Ewer, Pedro M Folegatti, Nick Edwards

Nat Med· February 2021

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Publisher Correction: ChAdOx1 nCoV-19 vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques.
Neeltje van Doremalen, Teresa Lambe, Alexandra Spencer, Sandra Belij-Rammerstorfer, Jyothi N Purushotham, Nick J Edwards

Nature· February 2021

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ChAdOx1 nCoV-19 vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques.
Neeltje van Doremalen, Teresa Lambe, Alexandra Spencer, Sandra Belij-Rammerstorfer, Jyothi N Purushotham, Nick J Edwards

Nature· October 2020

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A single dose of ChAdOx1 MERS provides protective immunity in rhesus macaques.
Neeltje van Doremalen, Elaine Haddock, Friederike Feldmann, Kimberly Meade-White, Trenton Bushmaker, Nick J Edwards

Sci Adv· June 2020

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Higher risk of xylitol gum poisoning with some products.
Nicola Bates, Nick Edwards, Nicola Robinson

Vet Rec· August 2019

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Safety and Immunogenicity of a Novel Recombinant Simian Adenovirus ChAdOx2 as a Vectored Vaccine.
Pedro M Folegatti, Duncan Bellamy, Rachel Roberts, Jonathan Powlson, Nick J Edwards

Vaccines (Basel)· May 2019

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