Publications by authors named "Nicolas Frances"

Claim this Profile
L
Leveraging in vitro Tumor Cell Killing and Cytokine Release to Predict Cytokine Release Syndrome Associated with CD3 T-cell Bispecifics in Oncology: a Retrospective Analysis.
Apolline Lefèvre, Zinnia P Parra-Guillen, Iñaki F Trocóniz, Christophe Boetsch, Nicolas Frances

AAPS J· November 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Semi-enzymatic synthesis and application of C-isotopically labelled inositol-(1,4,5)-trisphosphate.
Atharva Patharkar, Meike Amma, Jaime Isern, Zoé Chaudron, Angélique Besson-Bard

RSC Chem Biol· August 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Nitric oxide production and protein S-nitrosation in algae.
Zoé Chaudron, Valérie Nicolas-Francès, Carole Pichereaux, Siham Hichami, Claire Rosnoblet

Plant Sci· June 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A Model-Based Approach to Evaluate Anti-Drug Antibody Impact on Drug Exposure With Biologics: A Case Example With the CD3 T-Cell Bispecific Cibisatamab.
Javier Sanchez, Philippe B Pierrillas, Nicolas Frey, Gregor P Lotz, Siv Jönsson, Nicolas Frances

CPT Pharmacometrics Syst Pharmacol· June 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Mechanistic PKPD modeling to describe cytokine release associated with CD3 T-cell engager therapies.
Apolline Lefèvre, Zinnia P Parra-Guillen, Iñaki F Trocóniz, Christophe Boetsch, Nicolas Frances

Front Immunol· May 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Combining mathematical modeling, data and clinical target expression to support bispecific antibody binding affinity selection: a case example with FAP-4-1BBL.
Javier Sanchez, Christina Claus, Christine McIntyre, Tamara Tanos, Axel Boehnke, Nicolas Frances

Front Pharmacol· October 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
CDC48 regulates immunity pathway in tobacco plants.
Valérie Nicolas-Francès, Angélique Besson-Bard, Stefano Meschini, Agnès Klinguer, Aline Bonnotte

Plant Physiol Biochem· June 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A prognostic baseline blood biomarker and tumor growth kinetics integrated model in paclitaxel/platinum treated advanced non-small cell lung cancer patients.
Francis Williams Ojara, Andrea Henrich, Nicolas Frances, Yomna M Nassar, Wilhelm Huisinga

CPT Pharmacometrics Syst Pharmacol· November 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A model-based approach leveraging in vitro data to support dose selection from the outset: A framework for bispecific antibodies in immuno-oncology.
Javier Sánchez, Christina Claus, Rosmarie Albrecht, Brenda C Gaillard, Joana Marinho, Nicolas Frances

CPT Pharmacometrics Syst Pharmacol· November 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Correction: Preclinical In Vivo Data Integrated in a Modeling Network Informs a Refined Clinical Strategy for a CD3 T‑Cell Bispecific in Combination with Anti‑PD‑L1.
Javier Sánchez, Valeria Nicolini, Linda Fahrni, Inja Waldhauer, Antje-Christine Walz, Nicolas Frances

AAPS J· April 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Preclinical InVivo Data Integrated in a Modeling Network Informs a Refined Clinical Strategy for a CD3 T-Cell Bispecific in Combination with Anti-PD-L1.
Javier Sánchez, Valeria Nicolini, Linda Fahrni, Inja Waldhauer, Antje-Christine Walz, Nicolas Frances

AAPS J· October 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Novel in Vivo and in Vitro Pharmacokinetic/Pharmacodynamic-Based Human Starting Dose Selection for Glofitamab.
Nicolas Frances, Marina Bacac, Katharine Bray-French, François Christen, Heather Hinton

J Pharm Sci· April 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Preclinical Characterization of a Next-Generation Brain Permeable, Paradox Breaker BRAF Inhibitor.
Jürgen Wichmann, Caroline Rynn, Thomas Friess, Jeannine Petrig-Schaffland, Martin Kornacker, Nicolas Frances

Clin Cancer Res· February 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
S-Nitrosation of Protein Tyrosine Phosphatase 1 Prevents Its Irreversible Oxidation by Hydrogen Peroxide.
Valérie Nicolas-Francès, Jordan Rossi, Claire Rosnoblet, Carole Pichereaux, Siham Hichami

Front Plant Sci· February 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Nitric oxide production and signalling in algae.
Jeremy Astier, Jordan Rossi, Pauline Chatelain, Agnès Klinguer, Angélique Besson-Bard

J Exp Bot· February 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Predicting Tumor Killing and T-Cell Activation by T-Cell Bispecific Antibodies as a Function of Target Expression: Combining Experiments with Systems Modeling.
Arthur J Van De Vyver, Tina Weinzierl, Miro J Eigenmann, Nicolas Frances, Sylvia Herter

Mol Cancer Ther· February 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Time-to-Event Analysis of Paclitaxel-Associated Peripheral Neuropathy in Advanced Non-Small-Cell Lung Cancer Highlighting Key Influential Treatment/Patient Factors.
Francis W Ojara, Andrea Henrich, Nicolas Frances, Wilhelm Huisinga, Niklas Hartung

J Pharmacol Exp Ther· December 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A phase 1 healthy male volunteer single escalating dose study of the pharmacokinetics and pharmacodynamics of risdiplam (RG7916, RO7034067), a SMN2 splicing modifier.
Stefan Sturm, Andreas Günther, Birgit Jaber, Paul Jordan, Nada Al Kotbi, Nicolas Frances

Br J Clin Pharmacol· January 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Hematopoietic cells as site of first-pass catabolism after subcutaneous dosing and contributors to systemic clearance of a monoclonal antibody in mice.
Wolfgang F Richter, Gregory J Christianson, Nicolas Frances, Hans Peter Grimm, Gabriele Proetzel

MAbs· July 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Evolutionary diversification of type-2 HDAC structure, function and regulation in Nicotiana tabacum.
Valérie Nicolas-Francès, Vincent Grandperret, Benjamin Liegard, Sylvain Jeandroz, Damien Vasselon

Plant Sci· April 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
PKPD modeling of acquired resistance to anti-cancer drug treatment.
Miro J Eigenmann, Nicolas Frances, Thierry Lavé, Antje-Christine Walz

J Pharmacokinet Pharmacodyn· December 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Combining Nonclinical Experiments with Translational PKPD Modeling to Differentiate Erlotinib and Gefitinib.
Miro J Eigenmann, Nicolas Frances, Gerhard Hoffmann, Thierry Lavé, Antje-Christine Walz

Mol Cancer Ther· December 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The Evolution of HD2 Proteins in Green Plants.
S Bourque, S Jeandroz, V Grandperret, N Lehotai, S Aimé

Trends Plant Sci· December 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
NO signaling in plant immunity: a tale of messengers.
Pauline Trapet, Anna Kulik, Olivier Lamotte, Sylvain Jeandroz, Stéphane Bourque

Phytochemistry· April 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Translational PK/PD modeling for cardiovascular safety assessment of drug candidates: Methods and examples in drug development.
Antonello Caruso, Nicolas Frances, Christophe Meille, Andrea Greiter-Wilke, Alexander Hillebrecht

J Pharmacol Toxicol Methods· March 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis