Publications by authors named "Nicolas Ledru"

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Mosaic Loss of Y Chromosome Defines a Proximal Tubular Cell State Associated with Recovery from DGF and of Allograft Quality and Functional Reserve Post DCD Kidney Transplantation.
Andrew F Malone, Rohan Paul, Haikuo Li, Aidan Leckie-Harre, Haojia Wu, Nicolas Ledru

Ann Surg· July 2025

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Multiomics profiling of mouse polycystic kidney disease progression at a single-cell resolution.
Yoshiharu Muto, Yasuhiro Yoshimura, Haojia Wu, Monica Chang-Panesso, Nicolas Ledru

Proc Natl Acad Sci U S A· October 2024

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Epigenetic reprogramming driving successful and failed repair in acute kidney injury.
Yoshiharu Muto, Eryn E Dixon, Yasuhiro Yoshimura, Nicolas Ledru, Yuhei Kirita

Sci Adv· August 2024

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Transcriptomic, epigenomic, and spatial metabolomic cell profiling redefines regional human kidney anatomy.
Haikuo Li, Dian Li, Nicolas Ledru, Qiao Xuanyuan, Haojia Wu

Cell Metab· May 2024

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Multi-omics profiling of mouse polycystic kidney disease progression at a single cell resolution.
Yoshiharu Muto, Yasuhiro Yoshimura, Haojia Wu, Monica Chang-Panesso, Nicolas Ledru

bioRxiv· May 2024

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Predicting proximal tubule failed repair drivers through regularized regression analysis of single cell multiomic sequencing.
Nicolas Ledru, Parker C Wilson, Yoshiharu Muto, Yasuhiro Yoshimura, Haojia Wu

Nat Commun· February 2024

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Epigenetic reprogramming driving successful and failed repair in acute kidney injury.
Yoshiharu Muto, Eryn E Dixon, Yasuhiro Yoshimura, Nicolas Ledru, Yuhei Kirita

bioRxiv· January 2024

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A single-cell multiomic analysis of kidney organoid differentiation.
Yasuhiro Yoshimura, Yoshiharu Muto, Nicolas Ledru, Haojia Wu, Kohei Omachi

Proc Natl Acad Sci U S A· May 2023

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Defining cellular complexity in human autosomal dominant polycystic kidney disease by multimodal single cell analysis.
Yoshiharu Muto, Eryn E Dixon, Yasuhiro Yoshimura, Haojia Wu, Kohei Omachi, Nicolas Ledru

Nat Commun· October 2022

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Single cell transcriptional and chromatin accessibility profiling redefine cellular heterogeneity in the adult human kidney.
Yoshiharu Muto, Parker C Wilson, Nicolas Ledru, Haojia Wu, Henrik Dimke

Nat Commun· April 2021

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Alcohol Causes Lasting Differential Transcription in Mushroom Body Neurons.
Emily Petruccelli, Tariq Brown, Amanda Waterman, Nicolas Ledru, Karla R Kaun

Genetics· May 2020

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Epigenomics and the kidney.
Parker C Wilson, Nicolas Ledru, Benjamin D Humphreys

Curr Opin Nephrol Hypertens· May 2020

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The single-cell transcriptomic landscape of early human diabetic nephropathy.
Parker C Wilson, Haojia Wu, Yuhei Kirita, Kohei Uchimura, Nicolas Ledru

Proc Natl Acad Sci U S A· September 2019

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Alcohol Activates Scabrous-Notch to Influence Associated Memories.
Emily Petruccelli, Michael Feyder, Nicolas Ledru, Yanabah Jaques, Edward Anderson

Neuron· December 2018

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