Publications by authors named "Yuhei Kirita"

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Genetic deletion of the sodium phosphate cotransporter NaPi2a ameliorates heart failure in mice.
Hiroko Yamauchi-Sawada, Tomoharu Ida, Masashi Nakamura, Minato Umehara, Natsuko Okuno-Ozeki, Yuhei Kirita

Sci Rep· August 2025

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Injured tubule derived CCN1 exacerbates renal congestion-mediated acute kidney injury and fibrosis.
Atsushi Minamida, Tomohiro Nakata, Ryo Kurose, Shinji Sawai, Masashi Nakamura, Yuhei Kirita

Sci Rep· July 2025

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Toll like receptor 2 mediated exacerbation of sepsis associated acute kidney injury by renal congestion in mice.
Itaru Nakamura, Minato Umehara, Aya Yagi-Tomita, Satomi Yamamoto, Shinji Sawai, Yuhei Kirita

Sci Rep· July 2025

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Injured tubular epithelia-derived CCN1 promotes the mobilization of fibroblasts toward injury sites after kidney injury.
Tomohiro Nakata, Yuhei Kirita, Minato Umehara, Masashi Nakamura, Shinji Sawai

iScience· April 2025

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Epigenetic reprogramming driving successful and failed repair in acute kidney injury.
Yoshiharu Muto, Eryn E Dixon, Yasuhiro Yoshimura, Nicolas Ledru, Yuhei Kirita

Sci Adv· August 2024

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depletion induces inflammation and apoptosis in injured renal proximal tubule epithelial cells.
Shayna T J Bradford, Haojia Wu, Yuhei Kirita, Changfeng Chen, Nicole P Malvin

Am J Physiol Renal Physiol· May 2024

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Aversion to a High Salt Taste is Disturbed in Patients With CKD.
Natsuko Okuno-Ozeki, Yusuke Kohama, Hiromu Taguchi, Yuka Kawate, Minato Umehara, Yuhei Kirita

Kidney Int Rep· May 2024

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Rational in silico design identifies two mutations that restore UT28K SARS-CoV-2 monoclonal antibody activity against Omicron BA.1.
Tatsuhiko Ozawa, Yoshiki Ikeda, Liuan Chen, Rigel Suzuki, Atsushi Hoshino, Yuhei Kirita

Structure· March 2024

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The importance of proinflammatory failed-repair tubular epithelia as a predictor of diabetic kidney disease progression.
Aya Tomita-Yagi, Natsuko Ozeki-Okuno, Noriko Watanabe-Uehara, Kazumi Komaki, Minato Umehara, Yuhei Kirita

iScience· February 2024

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Epigenetic reprogramming driving successful and failed repair in acute kidney injury.
Yoshiharu Muto, Eryn E Dixon, Yasuhiro Yoshimura, Nicolas Ledru, Yuhei Kirita

bioRxiv· January 2024

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An AsCas12f-based compact genome-editing tool derived by deep mutational scanning and structural analysis.
Tomohiro Hino, Satoshi N Omura, Ryoya Nakagawa, Tomoki Togashi, Satoru N Takeda, Yuhei Kirita

Cell· October 2023

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Liver lipophagy ameliorates nonalcoholic steatohepatitis through extracellular lipid secretion.
Yoshito Minami, Atsushi Hoshino, Yusuke Higuchi, Masahide Hamaguchi, Yusaku Kaneko, Yuhei Kirita

Nat Commun· July 2023

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Structural delineation and computational design of SARS-CoV-2-neutralizing antibodies against Omicron subvariants.
Saya Moriyama, Yuki Anraku, Shunta Taminishi, Yu Adachi, Daisuke Kuroda, Yuhei Kirita

Nat Commun· July 2023

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Endothelial cell senescence exacerbates pulmonary hypertension by inducing juxtacrine Notch signaling in smooth muscle cells.
Risa Ramadhiani, Koji Ikeda, Kazuya Miyagawa, Gusty Rizky Tough Ryanto, Naoki Tamada, Yuhei Kirita

iScience· May 2023

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Streptozotocin induces renal proximal tubular injury through p53 signaling activation.
Kunihiro Nakai, Minato Umehara, Atsushi Minamida, Hiroko Yamauchi-Sawada, Yasuto Sunahara, Yuhei Kirita

Sci Rep· May 2023

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Lineage Tracing and Single-Nucleus Multiomics Reveal Novel Features of Adaptive and Maladaptive Repair after Acute Kidney Injury.
Louisa M S Gerhardt, Kari Koppitch, Jordi van Gestel, Jinjin Guo, Sam Cho, Yuhei Kirita

J Am Soc Nephrol· April 2023

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Deep Mutational Scanning to Predict Escape from Bebtelovimab in SARS-CoV-2 Omicron Subvariants.
Mellissa C Alcantara, Yusuke Higuchi, Yuhei Kirita, Satoaki Matoba, Atsushi Hoshino

Vaccines (Basel)· March 2023

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Proximal tubular epithelia-specific transcriptomics of diabetic mice treated with dapagliflozin.
Noriko Uehara-Watanabe, Natsuko Okuno-Ozeki, Itaru Nakamura, Tomohiro Nakata, Kunihiro Nakai, Yuhei Kirita

Heliyon· September 2022

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An engineered ACE2 decoy neutralizes the SARS-CoV-2 Omicron variant and confers protection against infection in vivo.
Nariko Ikemura, Shunta Taminishi, Tohru Inaba, Takao Arimori, Daisuke Motooka, Yuhei Kirita

Sci Transl Med· June 2022

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Kidney vascular congestion exacerbates acute kidney injury in mice.
Takashi Kitani, Kengo Kidokoro, Tomohiro Nakata, Yuhei Kirita, Itaru Nakamura

Kidney Int· March 2022

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Direct evidence of proximal tubular proliferation in early diabetic nephropathy.
Noriko Uehara-Watanabe, Natsuko Okuno-Ozeki, Atsushi Minamida, Itaru Nakamura, Tomohiro Nakata, Yuhei Kirita

Sci Rep· January 2022

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Cumulative DNA damage by repeated low-dose cisplatin injection promotes the transition of acute to chronic kidney injury in mice.
Noriyuki Yamashita, Kunihiro Nakai, Tomohiro Nakata, Itaru Nakamura, Yuhei Kirita

Sci Rep· October 2021

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Engineered ACE2 receptor therapy overcomes mutational escape of SARS-CoV-2.
Yusuke Higuchi, Tatsuya Suzuki, Takao Arimori, Nariko Ikemura, Emiko Mihara, Yuhei Kirita

Nat Commun· June 2021

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Intratubular epithelial-mesenchymal transition and tubular atrophy after kidney injury in mice.
Noriyuki Yamashita, Tetsuro Kusaba, Tomohiro Nakata, Aya Tomita, Tomoharu Ida, Yuhei Kirita

Am J Physiol Renal Physiol· October 2020

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Cell profiling of mouse acute kidney injury reveals conserved cellular responses to injury.
Yuhei Kirita, Haojia Wu, Kohei Uchimura, Parker C Wilson, Benjamin D Humphreys

Proc Natl Acad Sci U S A· July 2020

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