Publications by authors named "Nicole Clemann"

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Preclinical B cell depletion and safety profile of a brain-shuttled crystallizable fragment-silenced CD20 antibody.
Vanessa L Schumacher, Solen Pichereau, Juliana Bessa, Juergen Bachl, Sylvia Herter, Nicole Clemann

Clin Transl Med· March 2025

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Comparison of permitted daily exposure (PDE) values for active pharmaceutical ingredients (APIs) - Evidence of a robust approach.
Claudia Sehner, Tanja Bernier, Kamila Blum, Nicole Clemann, Milica Glogovac

Regul Toxicol Pharmacol· June 2024

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Optimization of the TeraTox Assay for Preclinical Teratogenicity Assessment.
Manuela Jaklin, Jitao David Zhang, Nicole Schäfer, Nicole Clemann, Paul Barrow

Toxicol Sci· June 2022

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Review of embryo-fetal developmental toxicity studies performed for pharmaceuticals approved by FDA in 2018 and 2019.
Paul Barrow, Nicole Clemann

Reprod Toxicol· January 2021

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Focus on germ-layer markers: A human stem cell-based model for in vitro teratogenicity testing.
Manuela Jaklin, Jitao David Zhang, Paul Barrow, Martin Ebeling, Nicole Clemann

Reprod Toxicol· December 2020

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StemBANCC: Governing Access to Material and Data in a Large Stem Cell Research Consortium.
Michael Morrison, Christine Klein, Nicole Clemann, David A Collier, John Hardy

Stem Cell Rev Rep· October 2015

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Metabotropic glutamate receptor 5 negative allosteric modulators: discovery of 2-chloro-4-[1-(4-fluorophenyl)-2,5-dimethyl-1H-imidazol-4-ylethynyl]pyridine (basimglurant, RO4917523), a promising novel medicine for psychiatric diseases.
Georg Jaeschke, Sabine Kolczewski, Will Spooren, Eric Vieira, Nadia Bitter-Stoll, Nicole Clemann

J Med Chem· February 2015

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The embryonic stem cell test for the early selection of pharmaceutical compounds.
Sonia Whitlow, Heinrich Bürgin, Nicole Clemann

ALTEX· June 2007

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Validation of the embryonic stem cell test in the international ECVAM validation study on three in vitro embryotoxicity tests.
Elke Genschow, Horst Spielmann, Gabriele Scholz, Ingeborg Pohl, Andrea Seiler, Nicole Clemann

Altern Lab Anim· September 2004

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Validation of the postimplantation rat whole-embryo culture test in the international ECVAM validation study on three in vitro embryotoxicity tests.
Aldert H Piersma, Elke Genschow, Aart Verhoef, Marielle Q I Spanjersberg, Nigel A Brown, Nicole Clemann

Altern Lab Anim· September 2004

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The ECVAM international validation study on in vitro embryotoxicity tests: results of the definitive phase and evaluation of prediction models. European Centre for the Validation of Alternative Methods.
Elke Genschow, Horst Spielmann, Gabriele Scholz, Andrea Seiler, Nigel Brown, Nicole Clemann

Altern Lab Anim· June 2002

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