Publications by authors named "Nigar Fatma"

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Sumoylation-deficient Prdx6 gains protective function by amplifying enzymatic activity and stability and escapes oxidative stress-induced aberrant Sumoylation.
Bhavana Chhunchha, Eri Kubo, Nigar Fatma, Dhirendra P Singh

Cell Death Dis· January 2017

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Delivery of a protein transduction domain-mediated Prdx6 protein ameliorates oxidative stress-induced injury in human and mouse neuronal cells.
Shatrunjai P Singh, Bhavana Chhunchha, Nigar Fatma, Eri Kubo, Sanjay P Singh

Am J Physiol Cell Physiol· January 2016

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Aberrant sumoylation signaling evoked by reactive oxygen species impairs protective function of Prdx6 by destabilization and repression of its transcription.
Bhavana Chhunchha, Nigar Fatma, Eri Kubo, Dhirendra P Singh

FEBS J· August 2014

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Curcumin abates hypoxia-induced oxidative stress based-ER stress-mediated cell death in mouse hippocampal cells (HT22) by controlling Prdx6 and NF-κB regulation.
Bhavana Chhunchha, Nigar Fatma, Eri Kubo, Prerana Rai, Sanjay P Singh

Am J Physiol Cell Physiol· April 2013

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Epigenetic repression of LEDGF during UVB exposure by recruitment of SUV39H1 and HDAC1 to the Sp1-responsive elements within LEDGF promoter CpG island.
Biju Bhargavan, Bhavana Chhunchha, Nigar Fatma, Eri Kubo, Anil Kumar

Epigenetics· March 2013

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Transcriptional protein Sp1 regulates LEDGF transcription by directly interacting with its cis-elements in GC-rich region of TATA-less gene promoter.
Dhirendra P Singh, Biju Bhargavan, Bhavana Chhunchha, Eri Kubo, Anil Kumar, Nigar Fatma

PLoS One· January 2013

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Elevated tropomyosin expression is associated with epithelial-mesenchymal transition of lens epithelial cells.
Eri Kubo, Nailia Hasanova, Nigar Fatma, Hiroshi Sasaki, Dhirendra P Singh

J Cell Mol Med· January 2013

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Lens epithelium-derived growth factor deSumoylation by Sumo-specific protease-1 regulates its transcriptional activation of small heat shock protein and the cellular response.
Keiichi Ishihara, Nigar Fatma, Biju Bhargavan, Bhavana Chhunchha, Eri Kubo

FEBS J· September 2012

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Deficiency of Prdx6 in lens epithelial cells induces ER stress response-mediated impaired homeostasis and apoptosis.
Nigar Fatma, Prerna Singh, Bhavana Chhunchha, Eri Kubo, T Shinohara

Am J Physiol Cell Physiol· October 2011

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Neuroprotective effect of peroxiredoxin 6 against hypoxia-induced retinal ganglion cell damage.
Rajkumar Tulsawani, Lorena S Kelly, Nigar Fatma, Bhavanaben Chhunchha, Eri Kubo

BMC Neurosci· October 2010

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Protein expression profiling of lens epithelial cells from Prdx6-depleted mice and their vulnerability to UV radiation exposure.
Eri Kubo, Nailia Hasanova, Yukie Tanaka, Nigar Fatma, Yoshihiro Takamura

Am J Physiol Cell Physiol· February 2010

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Anion-sensitive regions of L-type CaV1.2 calcium channels expressed in HEK293 cells.
Norbert Babai, Nataly Kanevsky, Nathan Dascal, George J Rozanski, Dhirendra P Singh, Nigar Fatma

PLoS One· January 2010

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PRDX6 attenuates oxidative stress- and TGFbeta-induced abnormalities of human trabecular meshwork cells.
Nigar Fatma, Eri Kubo, Carol B Toris, W D Stamer, Carl B Camras

Free Radic Res· September 2009

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Loss of NF-kappaB control and repression of Prdx6 gene transcription by reactive oxygen species-driven SMAD3-mediated transforming growth factor beta signaling.
Nigar Fatma, Eri Kubo, Yoshihiro Takamura, Keiichi Ishihara, Claudia Garcia

J Biol Chem· August 2009

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TAT-mediated peroxiredoxin 5 and 6 protein transduction protects against high-glucose-induced cytotoxicity in retinal pericytes.
Eri Kubo, Dhirendra P Singh, Nigar Fatma, Yoshio Akagi

Life Sci· June 2009

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Peroxiredoxin 6 delivery attenuates TNF-alpha-and glutamate-induced retinal ganglion cell death by limiting ROS levels and maintaining Ca2+ homeostasis.
Nigar Fatma, E Kubo, M Sen, N Agarwal, W B Thoreson

Brain Res· October 2008

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TAT-mediated PRDX6 protein transduction protects against eye lens epithelial cell death and delays lens opacity.
Eri Kubo, Nigar Fatma, Yoshio Akagi, David R Beier, Sanjay P Singh

Am J Physiol Cell Physiol· March 2008

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Development- and age-associated expression pattern of peroxiredoxin 6, and its regulation in murine ocular lens.
Eri Kubo, Tomoe Miyazawa, Nigar Fatma, Yoshio Akagi, Dhirendra P Singh

Mech Ageing Dev· March 2006

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Differential activity of kaempferol and quercetin in attenuating tumor necrosis factor receptor family signaling in bone cells.
Jian L Pang, Dennis A Ricupero, Su Huang, Nigar Fatma, Dhirendra P Singh

Biochem Pharmacol· March 2006

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Regulation of heavy subunit chain of gamma-glutamylcysteine synthetase by tumor necrosis factor-alpha in lens epithelial cells: role of LEDGF/p75.
Yoshihiro Takamura, Nigar Fatma, Eri Kubo, Dhirendra P Singh

Am J Physiol Cell Physiol· February 2006

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LEDGF regulation of alcohol and aldehyde dehydrogenases in lens epithelial cells: stimulation of retinoic acid production and protection from ethanol toxicity.
Nigar Fatma, Eri Kubo, Leo T Chylack, Toshimichi Shinohara, Yoshio Akagi

Am J Physiol Cell Physiol· August 2004

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Lens epithelium-derived growth factor relieves transforming growth factor-beta1-induced transcription repression of heat shock proteins in human lens epithelial cells.
Preeti Sharma, Nigar Fatma, Eri Kubo, Toshimichi Shinohara, Leo T Chylack

J Biol Chem· May 2003

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Cellular distribution of lens epithelium-derived growth factor (LEDGF) in the rat eye: loss of LEDGF from nuclei of differentiating cells.
Eri Kubo, Dhirendra P Singh, Nigar Fatma, Toshimichi Shinohara, Peggy Zelenka

Histochem Cell Biol· April 2003

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LEDGF, a survival factor, activates stress-related genes.
Toshimichi Shinohara, Dhirendra P Singh, Nigar Fatma

Prog Retin Eye Res· May 2002

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