Publications by authors named "Nigel Parry"

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Chimeric GB virus B genomes containing hepatitis C virus p7 are infectious in vivo.
Stephen Griffin, Rachel Trowbridge, Pia Thommes, Nigel Parry, David Rowlands

J Hepatol· December 2008

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Studies on acyl pyrrolidine inhibitors of HCV RNA-dependent RNA polymerase to identify a molecule with replicon antiviral activity.
George Burton, Thomas W Ku, Thomas J Carr, Terry Kiesow, Robert T Sarisky, Nigel R Parry

Bioorg Med Chem Lett· April 2007

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Optimization of novel acyl pyrrolidine inhibitors of hepatitis C virus RNA-dependent RNA polymerase leading to a development candidate.
Martin J Slater, Elizabeth M Amphlett, David M Andrews, Gianpaolo Bravi, George Burton, Nigel R Parry

J Med Chem· March 2007

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Development of cell-based assays for in vitro characterization of hepatitis C virus NS3/4A protease inhibitors.
Victoria Chung, Anthony R Carroll, Norman M Gray, Nigel R Parry, Pia A Thommes

Antimicrob Agents Chemother· April 2005

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Dimeric zanamivir conjugates with various linking groups are potent, long-lasting inhibitors of influenza neuraminidase including H5N1 avian influenza.
Simon J F Macdonald, Rachel Cameron, Derek A Demaine, Rob J Fenton, Graham Foster, Nigel Parry

J Med Chem· April 2005

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Potent and long-acting dimeric inhibitors of influenza virus neuraminidase are effective at a once-weekly dosing regimen.
Simon J F Macdonald, Keith G Watson, Rachel Cameron, David K Chalmers, Derek A Demaine, Nigel Parry

Antimicrob Agents Chemother· December 2004

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Pyrrolidine-5,5-trans-lactams. 4. Incorporation of a P3/P4 urea leads to potent intracellular inhibitors of hepatitis C virus NS3/4A protease.
Martin J Slater, Elizabeth M Amphlett, David M Andrews, Paul Bamborough, Seb J Carey, Nigel R Parry

Org Lett· November 2003

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Design and synthesis of pyrrolidine-5,5'-trans-lactams (5-oxo-hexahydropyrrolo[3,2-b]pyrroles) as novel mechanism-based inhibitors of human cytomegalovirus protease. 4. Antiviral activity and plasma stability.
Alan D Borthwick, Dave E Davies, Peter F Ertl, Anne M Exall, Terry M Haley, Nigel R Parry

J Med Chem· October 2003

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