Publications by authors named "Nikolaos Biris"

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Small molecule OPA1 inhibitors amplify cytochrome c release and reverse cancer cells resistance to Bcl-2 inhibitors.
Anna Pellattiero, Charlotte Quirin, Federico Magrin, Mattia Sturlese, Alberto Fracasso, Nikolaos Biris

Sci Adv· July 2025

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STAR-0215 is a Novel, Long-Acting Monoclonal Antibody Inhibitor of Plasma Kallikrein for the Potential Treatment of Hereditary Angioedema.
Vahe Bedian, Nikolaos Biris, Charles Omer, Jou-Ku Chung, James Fuller

J Pharmacol Exp Ther· November 2023

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An Efficient Opal-Suppressor Tryptophanyl Pair Creates New Routes for Simultaneously Incorporating up to Three Distinct Noncanonical Amino Acids into Proteins in Mammalian Cells.
Arianna O Osgood, Yunan Zheng, Soumya Jyoti Singha Roy, Nikolaos Biris, Myer Hussain

Angew Chem Int Ed Engl· May 2023

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Modulating mitofusins to control mitochondrial function and signaling.
Emmanouil Zacharioudakis, Bogos Agianian, Vasantha Kumar Mv, Nikolaos Biris, Thomas P Garner

Nat Commun· July 2022

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MFN2 agonists reverse mitochondrial defects in preclinical models of Charcot-Marie-Tooth disease type 2A.
Agostinho G Rocha, Antonietta Franco, Andrzej M Krezel, Jeanne M Rumsey, Justin M Alberti, Nikolaos Biris

Science· April 2018

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Identification of Neutrophil Exocytosis Inhibitors (Nexinhibs), Small Molecule Inhibitors of Neutrophil Exocytosis and Inflammation: DRUGGABILITY OF THE SMALL GTPase Rab27a.
Jennifer L Johnson, Mahalakshmi Ramadass, Jing He, Steven J Brown, Jinzhong Zhang, Nikolaos Biris

J Biol Chem· December 2016

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Correcting mitochondrial fusion by manipulating mitofusin conformations.
Antonietta Franco, Richard N Kitsis, Julie A Fleischer, Evripidis Gavathiotis, Opher S Kornfeld, Nikolaos Biris

Nature· December 2016

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Synthetic Antibodies Inhibit Bcl-2-associated X Protein (BAX) through Blockade of the N-terminal Activation Site.
Onyinyechukwu Uchime, Zhou Dai, Nikolaos Biris, David Lee, Sachdev S Sidhu

J Biol Chem· January 2016

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RING Dimerization Links Higher-Order Assembly of TRIM5α to Synthesis of K63-Linked Polyubiquitin.
Zinaida Yudina, Amanda Roa, Rory Johnson, Nikolaos Biris, Daniel A de Souza Aranha Vieira

Cell Rep· August 2015

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Rhesus monkey TRIM5α SPRY domain recognizes multiple epitopes that span several capsid monomers on the surface of the HIV-1 mature viral core.
Nikolaos Biris, Andrei Tomashevski, Akash Bhattacharya, Felipe Diaz-Griffero, Dmitri N Ivanov

J Mol Biol· December 2013

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Contribution of SUMO-interacting motifs and SUMOylation to the antiretroviral properties of TRIM5α.
Alberto Brandariz-Nuñez, Amanda Roa, Jose Carlos Valle-Casuso, Nikolaos Biris, Dmitri Ivanov

Virology· January 2013

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Structure of the rhesus monkey TRIM5α PRYSPRY domain, the HIV capsid recognition module.
Nikolaos Biris, Yang Yang, Alexander B Taylor, Andrei Tomashevski, Miao Guo

Proc Natl Acad Sci U S A· August 2012

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Specificity and affinity of Lac repressor for the auxiliary operators O2 and O3 are explained by the structures of their protein-DNA complexes.
Julija Romanuka, Gert E Folkers, Nikolaos Biris, Evgeny Tishchenko, Hans Wienk

J Mol Biol· July 2009

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A TAF4-homology domain from the corepressor ETO is a docking platform for positive and negative regulators of transcription.
Yufeng Wei, Shaohua Liu, Jörn Lausen, Christopher Woodrell, Seongeun Cho, Nikolaos Biris

Nat Struct Mol Biol· July 2007

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Influence of sequential oligopeptide carriers on the bioactive structure of conjugated epitopes: comparative study of the conformation of a Herpes simplex virus glycoprotein gD-1 epitope in the free and conjugated form, and protein "built-in" crystal structure.
Dimitrios Krikorian, Athanassios Stavrakoudis, Nikolaos Biris, Constantinos Sakarellos, David Andreu

Biopolymers· August 2006

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Disorder-order folding transitions underlie catalysis in the helicase motor of SecA.
Dimitra Keramisanou, Nikolaos Biris, Ioannis Gelis, Georgios Sianidis, Spyridoula Karamanou

Nat Struct Mol Biol· July 2006

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The relative orientation of the Arg and Asp side chains defined by a pseudodihedral angle as a key criterion for evaluating the structure-activity relationship of RGD peptides.
Sarantos Kostidis, Athanassios Stavrakoudis, Nikolaos Biris, Demokritos Tsoukatos, Constantinos Sakarellos

J Pept Sci· August 2004

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Structure and flexibility adaptation in nonspecific and specific protein-DNA complexes.
Charalampos G Kalodimos, Nikolaos Biris, Alexandre M J J Bonvin, Marc M Levandoski, Marc Guennuegues

Science· July 2004

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Effect of synthetic peptides corresponding to residues 313-332 of the alphaIIb subunit on platelet activation and fibrinogen binding to alphaIIbbeta3.
John V Mitsios, Afroditi P Tambaki, Morfis Abatzis, Nikolaos Biris, Maria Sakarellos-Daitsiotis

Eur J Biochem· February 2004

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Mapping the binding domains of the alpha(IIb) subunit. A study performed on the activated form of the platelet integrin alpha(IIb)beta(3).
Nikolaos Biris, Morfis Abatzis, John V Mitsios, Maria Sakarellos-Daitsiotis, Constantinos Sakarellos

Eur J Biochem· September 2003

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The Ac-RGD-NH2 peptide as a probe of slow conformational exchange of short linear peptides in DMSO.
Nikolaos Biris, Athanassios Stavrakoudis, Anastasia S Politou, Emmanuel Mikros, Maria Sakarellos-Daitsiotis

Biopolymers· May 2003

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