Publications by authors named "Nils Brunner"

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PANTAX: a phase Ib clinical trial of the efflux pump inhibitor SCO-101 in combination with gemcitabine and nab-paclitaxel in non-resectable or metastatic pancreatic cancer.
Susy Shim, Anke Reinacher-Schick, Anna-Lena Kraeft, Per Pfeiffer, Line Schmidt Tarpgaard

Invest New Drugs· April 2025

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Inhibition of ABCG2 by SCO-101 Enhances Chemotherapy Efficacy in Cancer.
Anamarija Pfeiffer, Luca Di Leo, Marc Baker Bechmann, Mubeen Nawabi, Sophie Ambjørner

Int J Mol Sci· April 2025

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The invariant chain CD74 protein is a cell surface binding partner of TIMP-1 in breast cancer cells.
Mikkel Høeberg, Julie Boertmann Noer, Mette Vixø Vistesen, Annette Bartels, Esben Matzen Bech

Mol Oncol· August 2023

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Proteomic Profiling of Colorectal Adenomas Identifies a Predictive Risk Signature for Development of Metachronous Advanced Colorectal Neoplasia.
Jacob Mathias Bech, Thilde Terkelsen, Annette Snejbjerg Bartels, Fabian Coscia, Sophia Doll

Gastroenterology· July 2023

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New use for old drugs: Epirubicin in colorectal cancer.
Line S Tarpgaard, Camilla Qvortrup, Signe L Nielsen, Jan Stenvang, Sönke Detlefsen

Acta Oncol· July 2021

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A Comprehensive RNA Study to Identify circRNA and miRNA Biomarkers for Docetaxel Resistance in Breast Cancer.
Peide Huang, Fengyu Li, Zongchao Mo, Chunyu Geng, Fang Wen

Front Oncol· May 2021

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Four phase 1 trials to evaluate the safety and pharmacokinetic profile of single and repeated dosing of SCO-101 in adult male and female volunteers.
Troels K Bergmann, Tore B Stage, Jan Stenvang, Palle Christophersen, Thomas A Jacobsen

Basic Clin Pharmacol Toxicol· October 2020

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Characterization of resistance to a recombinant hexameric Fas-ligand (APO010) in human cancer cell lines.
Haatisha Jandu, Annette Nielsen, Nils Brunner, Anker Hansen, Steen Knudsen

Exp Hematol· July 2020

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ABCG2 Protein Levels and Association to Response to First-Line Irinotecan-Based Therapy for Patients with Metastatic Colorectal Cancer.
Jesper Andreas Palshof, Camilla Natasha Cederbye, Estrid Vilma Solyom Høgdall, Tim Svenstrup Poulsen, Dorte Linnemann

Int J Mol Sci· July 2020

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Pharmacodynamic modelling reveals synergistic interaction between docetaxel and SCO-101 in a docetaxel-resistant triple negative breast cancer cell line.
Asbjørn Nøhr-Nielsen, Sofie Otzen Bagger, Nils Brünner, Jan Stenvang, Trine Meldgaard Lund

Eur J Pharm Sci· May 2020

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An Explorative Analysis of mRNA Expression as a Biomarker Test for FOLFIRI Treatment in Stage III Colon Cancer Patients: Results from Retrospective Analyses of the PETACC-3 Trial.
Jan Stenvang, Eva Budinská, Eric van Cutsem, Fred Bosman, Vlad Popovici

Cancers (Basel)· April 2020

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The Pyrazolo[3,4-d]pyrimidine Derivative, SCO-201, Reverses Multidrug Resistance Mediated by ABCG2/BCRP.
Sophie E B Ambjørner, Michael Wiese, Sebastian Christoph Köhler, Joen Svindt, Xamuel Loft Lund

Cells· March 2020

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Two open-label, single arm, non-randomized phase II studies of irinotecan for the treatment of metastatic breast cancer in patients with increased copy number of the topoisomerase I gene.
Iben Kümler, Eva Balslev, Jan Stenvang, Nils Brünner, Bent Ejlertsen

BMC Cancer· June 2019

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Overexpression of TIMP-1 and Sensitivity to Topoisomerase Inhibitors in Glioblastoma Cell Lines.
Charlotte Aaberg-Jessen, Louise Fogh, Mia Dahl Sørensen, Bo Halle, Nils Brünner

Pathol Oncol Res· January 2019

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lncRNA profile study reveals the mRNAs and lncRNAs associated with docetaxel resistance in breast cancer cells.
Peide Huang, Fengyu Li, Lin Li, Yuling You, Shizhi Luo

Sci Rep· December 2018

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Coexisting genomic aberrations associated with lymph node metastasis in breast cancer.
Li Bao, Zhaoyang Qian, Maria B Lyng, Ling Wang, Yuan Yu

J Clin Invest· June 2018

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Co-expression of TIMP-1 and its cell surface binding partner CD63 in glioblastomas.
Charlotte Aaberg-Jessen, Mia D Sørensen, Ana L S A Matos, José M Moreira, Nils Brünner

BMC Cancer· March 2018

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Comprehensive genomic analysis of Oesophageal Squamous Cell Carcinoma reveals clinical relevance.
Peina Du, Peide Huang, Xuanlin Huang, Xiangchun Li, Zhimin Feng

Sci Rep· November 2017

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Implications of ABCG2 Expression on Irinotecan Treatment of Colorectal Cancer Patients: A Review.
Dorte Lisbet Nielsen, Jesper Andreas Palshof, Nils Brünner, Jan Stenvang, Birgitte Martine Viuff

Int J Mol Sci· September 2017

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BMP-2 induces EMT and breast cancer stemness through Rb and CD44.
Peide Huang, Anan Chen, Weiyi He, Zhen Li, Guanglin Zhang

Cell Death Discov· July 2017

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Detection of colorectal neoplasia: Combination of eight blood-based, cancer-associated protein biomarkers.
Michael Wilhelmsen, Ib J Christensen, Louise Rasmussen, Lars N Jørgensen, Mogens R Madsen

Int J Cancer· March 2017

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Profiling of microRNAs in tumor interstitial fluid of breast tumors - a novel resource to identify biomarkers for prognostic classification and detection of cancer.
Ann Rita Halvorsen, Åslaug Helland, Pavel Gromov, Vera Timmermans Wielenga, Maj-Lis Møller Talman, Nils Brunner

Mol Oncol· February 2017

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Topoisomerase I copy number alterations as biomarker for irinotecan efficacy in metastatic colorectal cancer.
Jesper Andreas Palshof, Estrid Vilma Solyom Høgdall, Tim Svenstrup Poulsen, Dorte Linnemann, Benny Vittrup Jensen

BMC Cancer· January 2017

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Drug Resistance in Colorectal Cancer Cell Lines is Partially Associated with Aneuploidy Status in Light of Profiling Gene Expression.
Jiao Guo, Shaohang Xu, Xuanlin Huang, Lin Li, Congmin Zhang

J Proteome Res· November 2016

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Cytokine profiling of tumor interstitial fluid of the breast and its relationship with lymphocyte infiltration and clinicopathological characteristics.
Jaime A Espinoza, Shakila Jabeen, Richa Batra, Elena Papaleo, Vilde Haakensen, Nils Brunner

Oncoimmunology· October 2016

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