Publications by authors named "Jan Stenvang"

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ABCG2 protein expression in tumors of patients with non-resectable pancreatic cancer treated with gemcitabine and -paclitaxel.
Susy Shim, Mette Bak Nielsen, Mikkel Eld, Jan Stenvang, Rasmus Froberg Brøndum

Front Oncol· June 2025

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PANTAX: a phase Ib clinical trial of the efflux pump inhibitor SCO-101 in combination with gemcitabine and nab-paclitaxel in non-resectable or metastatic pancreatic cancer.
Susy Shim, Anke Reinacher-Schick, Anna-Lena Kraeft, Per Pfeiffer, Line Schmidt Tarpgaard, Jan Stenvang

Invest New Drugs· April 2025

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Inhibition of ABCG2 by SCO-101 Enhances Chemotherapy Efficacy in Cancer.
Anamarija Pfeiffer, Luca Di Leo, Marc Baker Bechmann, Mubeen Nawabi, Sophie Ambjørner, Jan Stenvang

Int J Mol Sci· April 2025

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The invariant chain CD74 protein is a cell surface binding partner of TIMP-1 in breast cancer cells.
Mikkel Høeberg, Julie Boertmann Noer, Mette Vixø Vistesen, Annette Bartels, Esben Matzen Bech, Jan Stenvang

Mol Oncol· August 2023

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Antibody-drug conjugates (ADCs) targeting trophoblast cell surface antigen 2 (Trop-2) and precision treatment of breast cancer.
Jan Stenvang, Peter Michael Vestlev, Benny Vittrup Jensen, Per Pfeiffer

Ann Transl Med· November 2022

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Reversal of ABCG2/BCRP-Mediated Multidrug Resistance by 5,3',5'-Trihydroxy-3,6,7,4'-Tetramethoxyflavone Isolated from the Australian Desert Plant Chinnock.
Malene J Petersen, Xamuel L Lund, Susan J Semple, Bevan Buirchell, Henrik Franzyk, Jan Stenvang

Biomolecules· October 2021

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New use for old drugs: Epirubicin in colorectal cancer.
Line S Tarpgaard, Camilla Qvortrup, Signe L Nielsen, Jan Stenvang, Sönke Detlefsen

Acta Oncol· July 2021

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A Comprehensive RNA Study to Identify circRNA and miRNA Biomarkers for Docetaxel Resistance in Breast Cancer.
Peide Huang, Fengyu Li, Zongchao Mo, Chunyu Geng, Fang Wen, Jan Stenvang

Front Oncol· May 2021

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Molecular Profiling of Docetaxel-Resistant Prostate Cancer Cells Identifies Multiple Mechanisms of Therapeutic Resistance.
Thiago S Lima, Diego Iglesias-Gato, Luciano D O Souza, Jan Stenvang, Diego S Lima

Cancers (Basel)· March 2021

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Four phase 1 trials to evaluate the safety and pharmacokinetic profile of single and repeated dosing of SCO-101 in adult male and female volunteers.
Troels K Bergmann, Tore B Stage, Jan Stenvang, Palle Christophersen, Thomas A Jacobsen

Basic Clin Pharmacol Toxicol· October 2020

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Characterization of resistance to a recombinant hexameric Fas-ligand (APO010) in human cancer cell lines.
Haatisha Jandu, Annette Nielsen, Nils Brunner, Anker Hansen, Steen Knudsen, Jan Stenvang

Exp Hematol· July 2020

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ABCG2 Protein Levels and Association to Response to First-Line Irinotecan-Based Therapy for Patients with Metastatic Colorectal Cancer.
Jesper Andreas Palshof, Camilla Natasha Cederbye, Estrid Vilma Solyom Høgdall, Tim Svenstrup Poulsen, Dorte Linnemann, Jan Stenvang

Int J Mol Sci· July 2020

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Pharmacodynamic modelling reveals synergistic interaction between docetaxel and SCO-101 in a docetaxel-resistant triple negative breast cancer cell line.
Asbjørn Nøhr-Nielsen, Sofie Otzen Bagger, Nils Brünner, Jan Stenvang, Trine Meldgaard Lund

Eur J Pharm Sci· May 2020

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An Explorative Analysis of mRNA Expression as a Biomarker Test for FOLFIRI Treatment in Stage III Colon Cancer Patients: Results from Retrospective Analyses of the PETACC-3 Trial.
Jan Stenvang, Eva Budinská, Eric van Cutsem, Fred Bosman, Vlad Popovici

Cancers (Basel)· April 2020

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The Pyrazolo[3,4-d]pyrimidine Derivative, SCO-201, Reverses Multidrug Resistance Mediated by ABCG2/BCRP.
Sophie E B Ambjørner, Michael Wiese, Sebastian Christoph Köhler, Joen Svindt, Xamuel Loft Lund, Jan Stenvang

Cells· March 2020

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Metallopeptidase inhibitor 1 (TIMP-1) promotes receptor tyrosine kinase c-Kit signaling in colorectal cancer.
Cathrine Nordgaard, Sophia Doll, Ana Laura de Souza Almeida Matos, Mikkel Høeberg, Julhash Uddin Kazi, Jan Stenvang

Mol Oncol· December 2019

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Gel-Based Proteomics of Clinical Samples Identifies Potential Serological Biomarkers for Early Detection of Colorectal Cancer.
Stine F Thorsen, Irina Gromova, Ib J Christensen, Simon Fredriksson, Claus L Andersen, Jan Stenvang

Int J Mol Sci· December 2019

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Two open-label, single arm, non-randomized phase II studies of irinotecan for the treatment of metastatic breast cancer in patients with increased copy number of the topoisomerase I gene.
Iben Kümler, Eva Balslev, Jan Stenvang, Nils Brünner, Bent Ejlertsen

BMC Cancer· June 2019

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lncRNA profile study reveals the mRNAs and lncRNAs associated with docetaxel resistance in breast cancer cells.
Peide Huang, Fengyu Li, Lin Li, Yuling You, Shizhi Luo, Jan Stenvang

Sci Rep· December 2018

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Therapeutic application of multipotent stem cells.
Hamed Mirzaei, Amirhossein Sahebkar, Laleh Shiri Sichani, Abdullah Moridikia, Sara Nazari, Jan Stenvang

J Cell Physiol· April 2018

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State of the art in microRNA as diagnostic and therapeutic biomarkers in chronic lymphocytic leukemia.
Hamed Mirzaei, Sima Fathullahzadeh, Razieh Khanmohammadi, Mansoreh Darijani, Fatemeh Momeni, Jan Stenvang

J Cell Physiol· February 2018

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Comprehensive genomic analysis of Oesophageal Squamous Cell Carcinoma reveals clinical relevance.
Peina Du, Peide Huang, Xuanlin Huang, Xiangchun Li, Zhimin Feng, Jan Stenvang

Sci Rep· November 2017

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Implications of ABCG2 Expression on Irinotecan Treatment of Colorectal Cancer Patients: A Review.
Dorte Lisbet Nielsen, Jesper Andreas Palshof, Nils Brünner, Jan Stenvang, Birgitte Martine Viuff

Int J Mol Sci· September 2017

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BMP-2 induces EMT and breast cancer stemness through Rb and CD44.
Peide Huang, Anan Chen, Weiyi He, Zhen Li, Guanglin Zhang, Jan Stenvang

Cell Death Discov· July 2017

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Topoisomerase I copy number alterations as biomarker for irinotecan efficacy in metastatic colorectal cancer.
Jesper Andreas Palshof, Estrid Vilma Solyom Høgdall, Tim Svenstrup Poulsen, Dorte Linnemann, Benny Vittrup Jensen, Jan Stenvang

BMC Cancer· January 2017

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