Publications by authors named "Nobuhiro Tanuma"

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[Targeting NAD metabolism in neuroendocrine carcinoma].
Nobuhiro Tanuma

Nihon Yakurigaku Zasshi· July 2025

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FDX2, an iron-sulfur cluster assembly factor, is essential to prevent cellular senescence, apoptosis or ferroptosis of ovarian cancer cells.
Shuko Miyahara, Mai Ohuchi, Miyuki Nomura, Eifumi Hashimoto, Tomoyoshi Soga, Nobuhiro Tanuma

J Biol Chem· September 2024

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Oncogenic K-Ras cannot overcome proliferation failure caused by loss of Ppp6c in mouse embryonic fibroblasts.
Mai Ito, Nobuhiro Tanuma, Yui Kotani, Kokoro Murai, Ayumi Kondo

FEBS Open Bio· April 2024

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Niacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma.
Miyuki Nomura, Mai Ohuchi, Yoshimi Sakamoto, Kei Kudo, Keisuke Yaku, Sei-Ichi Tanuma, Nobuhiro Tanuma

Nat Commun· December 2023

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PP6 deficiency in mice with KRAS mutation and Trp53 loss promotes early death by PDAC with cachexia-like features.
Katsuya Fukui, Miyuki Nomura, Kazuhiro Kishimoto, Nobuhiro Tanuma, Koreyuki Kurosawa

Cancer Sci· May 2022

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Ppp6c deficiency accelerates K-ras -induced tongue carcinogenesis.
Kazuhiro Kishimoto, Kosuke Kanazawa, Miyuki Nomura, Takuji Tanaka, Taeko Shigemoto-Kuroda, Nobuhiro Tanuma

Cancer Med· July 2021

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Ppp6c haploinsufficiency accelerates UV-induced BRAF(V600E)-initiated melanomagenesis.
Kosuke Kanazawa, Kazuhiro Kishimoto, Miyuki Nomura, Koreyuki Kurosawa, Hiroyuki Kato, Nobuhiro Tanuma

Cancer Sci· June 2021

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Robustness of a Cancer Profiling Test Using Formalin-fixed Paraffin Embedded Tumor Specimens.
Shin Ito, Ikuro Sato, Mai Mochizuki, Kazunori Yamaguchi, Keiichi Tamai, Nobuhiro Tanuma

Anticancer Res· March 2021

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Dietary intervention as a therapeutic for cancer.
Mami Morita, Kei Kudo, Hiroshi Shima, Nobuhiro Tanuma

Cancer Sci· February 2021

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Comparison of the ischemic and non-ischemic lung cancer metabolome reveals hyper activity of the TCA cycle and autophagy.
Naohiko Kikuchi, Tomoyoshi Soga, Miyuki Nomura, Taku Sato, Yoshimi Sakamoto, Nobuhiro Tanuma

Biochem Biophys Res Commun· September 2020

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Structural Basis of Beneficial Design for Effective Nicotinamide Phosphoribosyltransferase Inhibitors.
Sei-Ichi Tanuma, Kiyotaka Katsuragi, Takahiro Oyama, Atsushi Yoshimori, Yuri Shibasaki, Nobuhiro Tanuma

Molecules· August 2020

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Divergent metabolic responses dictate vulnerability to NAMPT inhibition in ovarian cancer.
Kei Kudo, Miyuki Nomura, Yoshimi Sakamoto, Shigemi Ito, Mami Morita, Nobuhiro Tanuma

FEBS Lett· May 2020

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Novel activating KRAS mutation candidates in lung adenocarcinoma.
Jiro Abe, Nobuhiro Tanuma, Miyuki Nomura, Shin Ito, Isao Kasugai

Biochem Biophys Res Commun· February 2020

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A metabolic vulnerability of small-cell lung cancer.
Miyuki Nomura, Mami Morita, Nobuhiro Tanuma

Oncotarget· August 2018

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Revisiting glucose metabolism in cancer: lessons from a PKM knock-in model.
Taku Sato, Mami Morita, Miyuki Nomura, Nobuhiro Tanuma

Mol Cell Oncol· August 2018

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Loss of protein phosphatase 6 in mouse keratinocytes enhances K-ras -driven tumor promotion.
Koreyuki Kurosawa, Yui Inoue, Yoichiro Kakugawa, Yoji Yamashita, Kosuke Kanazawa, Nobuhiro Tanuma

Cancer Sci· July 2018

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Pyruvate kinase type M2 contributes to the development of pancreatic ductal adenocarcinoma by regulating the production of metabolites and reactive oxygen species.
Misa Yokoyama, Nobuhiro Tanuma, Rie Shibuya, Takeharu Shiroki, Makoto Abue

Int J Oncol· March 2018

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PKM1 Confers Metabolic Advantages and Promotes Cell-Autonomous Tumor Cell Growth.
Mami Morita, Taku Sato, Miyuki Nomura, Yoshimi Sakamoto, Yui Inoue, Nobuhiro Tanuma

Cancer Cell· March 2018

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model of non-small cell lung cancer using mouse lung epithelial cells.
Taku Sato, Mami Morita, Ryota Tanaka, Yui Inoue, Miyuki Nomura, Nobuhiro Tanuma

Oncol Lett· December 2017

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Cysteinyl-tRNA synthetase governs cysteine polysulfidation and mitochondrial bioenergetics.
Takaaki Akaike, Tomoaki Ida, Fan-Yan Wei, Motohiro Nishida, Yoshito Kumagai, Nobuhiro Tanuma

Nat Commun· October 2017

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Enhanced expression of the M2 isoform of pyruvate kinase is involved in gastric cancer development by regulating cancer-specific metabolism.
Takeharu Shiroki, Misa Yokoyama, Nobuhiro Tanuma, Ryuhei Maejima, Keiichi Tamai

Cancer Sci· May 2017

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Embryonic MicroRNA-369 Controls Metabolic Splicing Factors and Urges Cellular Reprograming.
Masamitsu Konno, Jun Koseki, Koichi Kawamoto, Naohiro Nishida, Hidetoshi Matsui, Nobuhiro Tanuma

PLoS One· April 2016

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The protein phosphatase 6 catalytic subunit (Ppp6c) is indispensable for proper post-implantation embryogenesis.
Honami Ogoh, Nobuhiro Tanuma, Yasuhisa Matsui, Natsuki Hayakawa, Ayaka Inagaki

Mech Dev· February 2016

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Nuclear pyruvate kinase M2 complex serves as a transcriptional coactivator of arylhydrocarbon receptor.
Shun Matsuda, Jun Adachi, Masaru Ihara, Nobuhiro Tanuma, Hiroshi Shima

Nucleic Acids Res· January 2016

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Mice doubly-deficient in the Arf GAPs SMAP1 and SMAP2 exhibit embryonic lethality.
Mami Sumiyoshi, Narumi Masuda, Nobuhiro Tanuma, Honami Ogoh, Eri Imai

FEBS Lett· September 2015

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