Publications by authors named "Norbert Lehming"

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Mitochondria and the Repurposing of Diabetes Drugs for Off-Label Health Benefits.
Joyce Mei Xin Yip, Grace Shu Hui Chiang, Ian Chong Jin Lee, Rachel Lehming-Teo, Kexin Dai, Norbert Lehming

Int J Mol Sci· January 2025

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Systematic Approaches to Study Eclipsed Targeting of Proteins Uncover a New Family of Mitochondrial Proteins.
Maayan Mark, Ofir Klein, Yu Zhang, Koyeli Das, Adi Elbaz, Norbert Lehming

Cells· June 2023

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Ubiquitination Occurs in the Mitochondrial Matrix by Eclipsed Targeted Components of the Ubiquitination Machinery.
Yu Zhang, Ofri Karmon, Koyeli Das, Reuven Wiener, Norbert Lehming

Cells· December 2022

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Fumarase affects the deoxyribonucleic acid damage response by protecting the mitochondrial desulfurase Nfs1p from modification and inactivation.
Joyce Yip, Suqing Wang, Jasper Tan, Teck Kwang Lim, Qingsong Lin, Norbert Lehming

iScience· November 2021

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A combination of Class-I fumarases and metabolites (α-ketoglutarate and fumarate) signal the DNA damage response in .
Yardena Silas, Esti Singer, Koyeli Das, Norbert Lehming, Ophry Pines

Proc Natl Acad Sci U S A· June 2021

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Post-translational Modifications of Fumarase Regulate its Enzyme Activity and Function in Respiration and the DNA Damage Response.
Suqing Wang, Dharanidharan Ramamurthy, Jasper Tan, Jingyan Liu, Joyce Yip, Norbert Lehming

J Mol Biol· November 2020

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Fumarase: From the TCA Cycle to DNA Damage Response and Tumor Suppression.
Michael Leshets, Yardena B H Silas, Norbert Lehming, Ophry Pines

Front Mol Biosci· July 2018

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Fumarase is involved in DNA double-strand break resection through a functional interaction with Sae2.
Michael Leshets, Dharanidharan Ramamurthy, Michael Lisby, Norbert Lehming, Ophry Pines

Curr Genet· June 2018

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Human Fumarate Hydratase Is Dual Localized by an Alternative Transcription Initiation Mechanism.
Ekaterina Dik, Adi Naamati, Hadar Asraf, Norbert Lehming, Ophry Pines

Traffic· July 2016

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Differential regulation of proinflammatory cytokine expression by mitogen-activated protein kinases in macrophages in response to intestinal parasite infection.
Mei Xing Lim, Chin Wen Png, Crispina Yan Bing Tay, Joshua Ding Wei Teo, Huipeng Jiao, Norbert Lehming

Infect Immun· November 2014

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How the ubiquitin proteasome system regulates the regulators of transcription.
Gary Ee, Norbert Lehming

Transcription· November 2013

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Mediator acts upstream of the transcriptional activator Gal4.
Keven Ang, Gary Ee, Edwin Ang, Elvin Koh, Wee Leng Siew, Norbert Lehming

PLoS Biol· July 2012

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Molecular analysis of Plasmodium falciparum co-chaperone Aha1 supports its interaction with and regulation of Hsp90 in the malaria parasite.
Chun Song Chua, Huiyu Low, Norbert Lehming, T S Sim

Int J Biochem Cell Biol· January 2012

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The histone variant H2A.Z interconverts two stable epigenetic chromatin states.
Jin Zhao, Wee Leng Siew, Weiqi Sun, Norbert Lehming

Biochem J· November 2011

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Galactose induction of the GAL1 gene requires conditional degradation of the Mig2 repressor.
Mei Kee Lim, Wee Leng Siew, Jin Zhao, Ywee Chieh Tay, Edwin Ang, Norbert Lehming

Biochem J· May 2011

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Transcriptional activation requires protection of the TATA-binding protein Tbp1 by the ubiquitin-specific protease Ubp3.
Boon Shang Chew, Wee Leng Siew, Benjamin Xiao, Norbert Lehming

Biochem J· November 2010

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Degradation-resistant protein domains limit host cell processing and immune detection of mycobacteria.
Kah Wee Koh, Norbert Lehming, Geok Teng Seah

Mol Immunol· April 2009

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Nhp6p and Med3p regulate gene expression by controlling the local subunit composition of RNA polymerase II.
Xiaowei Xue, Norbert Lehming

J Mol Biol· May 2008

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Gal11p dosage-compensates transcriptional activator deletions via Taf14p.
Mei Kee Lim, Vivien Tang, Agnès Le Saux, Jutta Schüller, Christine Bongards, Norbert Lehming

J Mol Biol· November 2007

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TFIIB/SUA7(E202G) is an allele-specific suppressor of TBP1(E186D).
Boon Shang Chew, Norbert Lehming

Biochem J· September 2007

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Global effects of histone modifications.
Hongpeng He, Norbert Lehming

Brief Funct Genomic Proteomic· October 2003

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The cyclin in the RNA polymerase holoenzyme is a target for the transcriptional repressor Tup1p in Saccharomyces cerevisiae.
Jutta Schüller, Norbert Lehming

J Mol Microbiol Biotechnol· September 2003

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The TATA-binding protein is not an essential target of the transcriptional activators Gal4p and Gcn4p in Saccharomyces cerevisiae.
Christine Bongards, Boon Shang Chew, Norbert Lehming

Biochem J· February 2003

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Transcriptional activating regions target a cyclin-dependent kinase.
Aseem Z Ansari, Sang Seok Koh, Zafar Zaman, Christine Bongards, Norbert Lehming

Proc Natl Acad Sci U S A· November 2002

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Analysis of protein-protein proximities using the split-ubiquitin system.
Norbert Lehming

Brief Funct Genomic Proteomic· October 2002

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