Publications by authors named "Ophry Pines"

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Biogenesis and function of the mitochondrial solute carrier (SLC25) family in yeast.
Celina Nauerz, Ophry Pines, Johannes M Herrmann

Biol Chem· December 2025

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Privileged proteins with a second residence: dual targeting and conditional re-routing of mitochondrial proteins.
Ophry Pines, Margalit Horwitz, Johannes M Herrmann

FEBS J· December 2024

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Mitochondrial derived vesicles- Quo Vadis?
Reut Hazan Ben-Menachem, Ophry Pines, Ann Saada

FEBS J· November 2024

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Systematic Approaches to Study Eclipsed Targeting of Proteins Uncover a New Family of Mitochondrial Proteins.
Maayan Mark, Ofir Klein, Yu Zhang, Koyeli Das, Adi Elbaz, Ophry Pines

Cells· June 2023

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Mitochondrial-derived vesicles retain membrane potential and contain a functional ATP synthase.
Reut Hazan Ben-Menachem, Dvora Lintzer, Tamar Ziv, Koyeli Das, Irit Rosenhek-Goldian, Ophry Pines

EMBO Rep· May 2023

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Ubiquitination Occurs in the Mitochondrial Matrix by Eclipsed Targeted Components of the Ubiquitination Machinery.
Yu Zhang, Ofri Karmon, Koyeli Das, Reuven Wiener, Norbert Lehming, Ophry Pines

Cells· December 2022

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Inactive Proteasomes Routed to Autophagic Turnover Are Confined within the Soluble Fraction of the Cell.
Keren Friedman, Ofri Karmon, Uri Fridman, Yair Goldberg, Ophry Pines

Biomolecules· December 2022

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Depletion of Fumarate Hydratase, an Essential TCA Cycle Enzyme, Drives Proliferation in a Two-Step Model.
Balakrishnan Solaimuthu, Michal Lichtenstein, Arata Hayashi, Anees Khatib, Inbar Plaschkes, Ophry Pines

Cancers (Basel)· November 2022

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Fumarase affects the deoxyribonucleic acid damage response by protecting the mitochondrial desulfurase Nfs1p from modification and inactivation.
Joyce Yip, Suqing Wang, Jasper Tan, Teck Kwang Lim, Qingsong Lin, Ophry Pines

iScience· November 2021

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A combination of Class-I fumarases and metabolites (α-ketoglutarate and fumarate) signal the DNA damage response in .
Yardena Silas, Esti Singer, Koyeli Das, Norbert Lehming, Ophry Pines

Proc Natl Acad Sci U S A· June 2021

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Post-translational Modifications of Fumarase Regulate its Enzyme Activity and Function in Respiration and the DNA Damage Response.
Suqing Wang, Dharanidharan Ramamurthy, Jasper Tan, Jingyan Liu, Joyce Yip, Ophry Pines

J Mol Biol· November 2020

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Haploinsufficiency due to a novel ACO2 deletion causes mitochondrial dysfunction in fibroblasts from a patient with dominant optic nerve atrophy.
Marie Anne-Catherine Neumann, Dajana Grossmann, Simone Schimpf-Linzenbold, Dana Dayan, Katarina Stingl, Ophry Pines

Sci Rep· October 2020

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A combination of two novel VARS2 variants causes a mitochondrial disorder associated with failure to thrive and pulmonary hypertension.
Hui-Lin Chin, Denise Li-Meng Goh, Furene Sijia Wang, Stacey Kiat Hong Tay, Chew Kiat Heng, Ophry Pines

J Mol Med (Berl)· November 2019

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Author Correction: Genome-wide SWAp-Tag yeast libraries for proteome exploration.
Uri Weill, Ido Yofe, Ehud Sass, Bram Stynen, Dan Davidi, Ophry Pines

Nat Methods· February 2019

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Genome-wide SWAp-Tag yeast libraries for proteome exploration.
Uri Weill, Ido Yofe, Ehud Sass, Bram Stynen, Dan Davidi, Ophry Pines

Nat Methods· August 2018

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Fumarase: From the TCA Cycle to DNA Damage Response and Tumor Suppression.
Michael Leshets, Yardena B H Silas, Norbert Lehming, Ophry Pines

Front Mol Biosci· July 2018

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Fumarase is involved in DNA double-strand break resection through a functional interaction with Sae2.
Michael Leshets, Dharanidharan Ramamurthy, Michael Lisby, Norbert Lehming, Ophry Pines

Curr Genet· June 2018

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Yeast aconitase mitochondrial import is modulated by interactions of its C and N terminal domains and Ssa1/2 (Hsp70).
Reut Ben-Menachem, Katherine Wang, Orly Marcu, Zhang Yu, Teck Kwang Lim, Ophry Pines

Sci Rep· April 2018

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Detection of Dual Targeting and Dual Function of Mitochondrial Proteins in Yeast.
Reut Ben-Menachem, Ophry Pines

Methods Mol Biol· February 2018

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Bacterial fumarase and L-malic acid are evolutionary ancient components of the DNA damage response.
Esti Singer, Yardena Bh Silas, Sigal Ben-Yehuda, Ophry Pines

Elife· November 2017

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Specialized function of yeast Isa1 and Isa2 proteins in the maturation of mitochondrial [4Fe-4S] proteins.
Ulrich Mühlenhoff, Nadine Richter, Ophry Pines, Antonio J Pierik, Roland Lill

J Biol Chem· October 2017

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Homozygous mutation, p.Pro304His, in IDH3A, encoding isocitrate dehydrogenase subunit is associated with severe encephalopathy in infancy.
Aviva Fattal-Valevski, Hila Eliyahu, NItai D Fraenkel, Ganit Elmaliach, Moran Hausman-Kedem, Ophry Pines

Neurogenetics· January 2017

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Human Fumarate Hydratase Is Dual Localized by an Alternative Transcription Initiation Mechanism.
Ekaterina Dik, Adi Naamati, Hadar Asraf, Norbert Lehming, Ophry Pines

Traffic· July 2016

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Cytosolic Hsp60 can modulate proteasome activity in yeast.
Bella Kalderon, Gleb Kogan, Ettel Bubis, Ophry Pines

J Biol Chem· February 2015

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Dual-targeted proteins tend to be more evolutionarily conserved.
Irit Kisslov, Adi Naamati, Nitzan Shakarchy, Ophry Pines

Mol Biol Evol· October 2014

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