Publications by authors named "Ohara Augusto"

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HyPer7: High-level bacterial expression and kinetics showing significant oxidation by peroxynitrite and hypochlorous acid.
Edlaine Linares, Fernando R Coelho, Natalia E Lemos, Thiago G P Alegria, Luis Es Netto, Ohara Augusto

Free Radic Biol Med· December 2025

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Presence of dysfunctional soluble guanylate cyclase in mesenteric resistance arteries from rats with mild ligature-induced periodontitis.
Flavia Neto de Jesus, Simone Aparecida Teixeira, Leonardo André da Costa Marques, Marinella Holzhausen, Camila Ferreira Wenceslau, Ohara Augusto

Eur J Pharmacol· July 2025

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Production of Peroxymonocarbonate by Steady-State Micromolar HO and Activated Macrophages in the Presence of CO/HCO Evidenced by Boronate Probes.
Edlaine Linares, Divinomar Severino, Daniela R Truzzi, Natalia Rios, Rafael Radi, Ohara Augusto

Chem Res Toxicol· July 2024

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Carbon dioxide redox metabolites in oxidative eustress and oxidative distress.
Ohara Augusto, Daniela Ramos Truzzi

Biophys Rev· December 2021

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Dinitrosyl Iron Complexes (DNICs). From Spontaneous Assembly to Biological Roles.
Daniela R Truzzi, Nathalia M Medeiros, Ohara Augusto, Peter C Ford

Inorg Chem· November 2021

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Oxidative Modification of Proteins: From Damage to Catalysis, Signaling, and Beyond.
Marilene Demasi, Ohara Augusto, Etelvino J H Bechara, Renata N Bicev, Fernanda M Cerqueira

Antioxid Redox Signal· October 2021

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Erratum to .
Lucas S Dantas, Lucas G Viviani, Alex Inague, Erika Piccirillo, Leandro de Rezende, Ohara Augusto

Free Radic Biol Med· January 2021

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Human cataractous lenses contain cross-links produced by crystallin-derived tryptophanyl and tyrosyl radicals.
Verônica Paviani, Paulo Junqueira de Melo, Amaryllis Avakin, Paolo Di Mascio, Graziella Eliza Ronsein, Ohara Augusto

Free Radic Biol Med· November 2020

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Tempol reduces inflammation and oxidative damage in cigarette smoke-exposed mice by decreasing neutrophil infiltration and activating the Nrf2 pathway.
Danielba Almeida da Silva, Thiago Macêdo Lopes Correia, Rafael Pereira, Robson Amaro Augusto da Silva, Ohara Augusto

Chem Biol Interact· September 2020

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Lipid aldehyde hydrophobicity affects apo-SOD1 modification and aggregation.
Lucas S Dantas, Lucas G Viviani, Alex Inague, Erika Piccirillo, Leandro de Rezende, Ohara Augusto

Free Radic Biol Med· August 2020

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Singlet oxygen generation by the reaction of acrolein with peroxynitrite via a 2-hydroxyvinyl radical intermediate.
Leticia C P Gonçalves, Júlio Massari, Saymon Licciardi, Fernanda M Prado, Edlaine Linares, Ohara Augusto

Free Radic Biol Med· May 2020

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The Peroxidatic Thiol of Peroxiredoxin 1 is Nitrosated by Nitrosoglutathione but Coordinates to the Dinitrosyl Iron Complex of Glutathione.
Daniela R Truzzi, Simone V Alves, Luis E S Netto, Ohara Augusto

Antioxidants (Basel)· March 2020

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Dynamics of Dinitrosyl Iron Complex (DNIC) Formation with Low Molecular Weight Thiols.
Daniela R Truzzi, Ohara Augusto, Alexei V Iretskii, Peter C Ford

Inorg Chem· October 2019

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The bicarbonate/carbon dioxide pair increases hydrogen peroxide-mediated hyperoxidation of human peroxiredoxin 1.
Daniela R Truzzi, Fernando R Coelho, Veronica Paviani, Simone V Alves, Luis E S Netto, Ohara Augusto

J Biol Chem· September 2019

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Thiyl radicals are co-products of dinitrosyl iron complex (DNIC) formation.
Daniela R Truzzi, Ohara Augusto, Peter C Ford

Chem Commun (Camb)· August 2019

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Carbon dioxide-catalyzed peroxynitrite reactivity - The resilience of the radical mechanism after two decades of research.
Ohara Augusto, Sara Goldstein, James K Hurst, Johan Lind, Sergei V Lymar

Free Radic Biol Med· May 2019

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Cholesterol secosterol aldehyde adduction and aggregation of Cu,Zn-superoxide dismutase: Potential implications in ALS.
Lucas S Dantas, Adriano B Chaves-Filho, Fernando R Coelho, Thiago C Genaro-Mattos, Keri A Tallman, Ohara Augusto

Redox Biol· October 2018

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The labile iron pool attenuates peroxynitrite-dependent damage and can no longer be considered solely a pro-oxidative cellular iron source.
Fernando Cruvinel Damasceno, André Luis Condeles, Angélica Kodama Bueno Lopes, Rômulo Rodrigues Facci, Edlaine Linares, Ohara Augusto

J Biol Chem· June 2018

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Peroxynitrite preferentially oxidizes the dithiol redox motifs of protein-disulfide isomerase.
Álbert Souza Peixoto, R Ryan Geyer, Asif Iqbal, Daniela R Truzzi, Ana I Soares Moretti, Ohara Augusto

J Biol Chem· January 2018

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Urate hydroperoxide oxidizes human peroxiredoxin 1 and peroxiredoxin 2.
Larissa A C Carvalho, Daniela R Truzzi, Thamiris S Fallani, Simone V Alves, José Carlos Toledo, Ohara Augusto

J Biol Chem· May 2017

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Kinetics, subcellular localization, and contribution to parasite virulence of a hybrid type A heme peroxidase (APx-CcP).
Martín Hugo, Alejandra Martínez, Madia Trujillo, Damián Estrada, Mauricio Mastrogiovanni, Ohara Augusto

Proc Natl Acad Sci U S A· February 2017

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Ohr plays a central role in bacterial responses against fatty acid hydroperoxides and peroxynitrite.
Thiago G P Alegria, Diogo A Meireles, José R R Cussiol, Martín Hugo, Madia Trujillo, Ohara Augusto

Proc Natl Acad Sci U S A· January 2017

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Catalytic Thr or Ser Residue Modulates Structural Switches in 2-Cys Peroxiredoxin by Distinct Mechanisms.
Carlos A Tairum, Melina Cardoso Santos, Carlos A Breyer, R Ryan Geyer, Cecilia J Nieves, Ohara Augusto

Sci Rep· September 2016

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Aromatic thiol-mediated cleavage of N-O bonds enables chemical ubiquitylation of folded proteins.
Caroline E Weller, Abhinav Dhall, Feizhi Ding, Edlaine Linares, Samuel D Whedon, Ohara Augusto

Nat Commun· September 2016

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New antibacterial agents: Hybrid bioisoster derivatives as potential E. coli FabH inhibitors.
Natanael D Segretti, Ricardo A M Serafim, Mariana C F Segretti, Marcelo Miyata, Fernando R Coelho, Ohara Augusto

Bioorg Med Chem Lett· August 2016

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