Publications by authors named "Ole Pless"

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Cortical organoid-derived models of the melanoma brain metastatic niche enable prioritization of cancer-targeting drugs.
Kim Krieg, Silvia Materna-Reichelt, Tobias Naber, Fatima-Zahra Rachad, Pia Kauven, Ole Pless

Cell Rep Methods· December 2025

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Linker Modification Enables Control of Key Functional Group Orientation in Macrocycles.
Christian Brudy, Enrico Ruijsenaars, Christian Meyners, Wisely O Sugiarto, Hanaa Achaq, Ole Pless

J Med Chem· December 2025

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Morphological profiling reveals neuroprotection via mitochondrial uncoupling in human dopaminergic neurons.
Vyron Gorgogietas, Amélie Weiss, Loïc Cousin, David Hoffmann, Karen Schmitt, Ole Pless

Sci Rep· August 2025

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Optimization and Evaluation of Complementary Degrader Discovery Assays for Application in Screening.
Johanna Huchting, Arjen Weller, Moyra Schweizer, Mona Brandt, Jan Heering, Ole Pless

ACS Pharmacol Transl Sci· August 2025

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Generation of two isogenic human iPSC lines (ZIPi013-B-1, ZIPi013-B-2) carrying a CRISPR/Cas9-mediated deletion of TRPM4.
Undine Haferkamp, Narasimha Telugu, Kim Krieg, Wiebe Schaefer, Dennis Lam, Ole Pless

Stem Cell Res· December 2024

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Identification and development of TRPM4 antagonists to counteract neuronal excitotoxicity.
Lars Binkle-Ladisch, Andy Pironet, Andrea Zaliani, Chantal Alcouffe, Daniel Mensching, Ole Pless

iScience· December 2024

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The NR4A2/VGF pathway fuels inflammation-induced neurodegeneration via promoting neuronal glycolysis.
Marcel S Woo, Lukas C Bal, Ingo Winschel, Elias Manca, Mark Walkenhorst, Ole Pless

J Clin Invest· June 2024

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Author Correction: Automated real-time monitoring of human pluripotent stem cell aggregation in stirred tank reactors.
Ivo Schwedhelm, Daniela Zdzieblo, Antje Appelt-Menzel, Constantin Berger, Tobias Schmitz, Ole Pless

Sci Rep· April 2024

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MicroRNA-92a-CPEB3 axis protects neurons against inflammatory neurodegeneration.
Iris Winkler, Jan Broder Engler, Vanessa Vieira, Simone Bauer, Yi-Hsiang Liu, Ole Pless

Sci Adv· November 2023

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Human isogenic cells of the neurovascular unit exert transcriptomic cell type-specific effects on a blood-brain barrier in vitro model of late-onset Alzheimer disease.
Undine Haferkamp, Carla Hartmann, Chaudhry Luqman Abid, Andreas Brachner, Alevtina Höchner, Ole Pless

Fluids Barriers CNS· October 2023

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Generation of a set of induced pluripotent stem cell lines from two Alzheimer disease patients carrying APOE4 (MLUi007-J; MLUi008-A) and healthy old donors carrying APOE3 (MLUi009-A; MLUi010-B) to study APOE in aging and disease.
Matthias Jung, Carla Hartmann, Toni Ehrhardt, Lisa-Maria Peter, Chaudhry Luqman Abid, Ole Pless

Stem Cell Res· June 2023

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High-content screening of mitochondrial polarization in neural cells derived from human pluripotent stem cells.
Annika Zink, Undine Haferkamp, Annika Wittich, Mathias Beller, Ole Pless

STAR Protoc· September 2022

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The mechanism of macroautophagy: The movie.
Fulvio Reggiori, Patricia Boya, David da Costa, Zvulun Elazar, Eeva-Liisa Eskelinen, Ole Pless

Autophagy Rep· September 2022

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G9a dictates neuronal vulnerability to inflammatory stress via transcriptional control of ferroptosis.
Nicola Rothammer, Marcel S Woo, Simone Bauer, Lars Binkle-Ladisch, Giovanni Di Liberto, Ole Pless

Sci Adv· August 2022

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Response to: SARS-CoV-2 and type I interferon signaling in brain endothelial cells: Blurring the lines between friend or foe.
Susanne Krasemann, Markus Glatzel, Ole Pless

Stem Cell Reports· May 2022

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Targeting autophagy in disease: established and new strategies.
Muhammed Kocak, Saba Ezazi Erdi, Guillem Jorba, Inés Maestro, Judith Farrés, Ole Pless

Autophagy· March 2022

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A hybrid approach unveils drug repurposing candidates targeting an Alzheimer pathophysiology mechanism.
Vanessa Lage-Rupprecht, Bruce Schultz, Justus Dick, Marcin Namysl, Andrea Zaliani, Ole Pless

Patterns (N Y)· March 2022

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The blood-brain barrier is dysregulated in COVID-19 and serves as a CNS entry route for SARS-CoV-2.
Susanne Krasemann, Undine Haferkamp, Susanne Pfefferle, Marcel S Woo, Fabian Heinrich, Ole Pless

Stem Cell Reports· February 2022

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Droplet-based vitrification of adherent human induced pluripotent stem cells on alginate microcarrier influenced by adhesion time and matrix elasticity.
Ina Meiser, Julia Majer, Alisa Katsen-Globa, André Schulz, Katharina Schmidt, Ole Pless

Cryobiology· December 2021

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Culturing human iPSC-derived neural progenitor cells on nanowire arrays: mapping the impact of nanowire length and array pitch on proliferation, viability, and membrane deformation.
Jann Harberts, Katja Bours, Malte Siegmund, Carina Hedrich, Michael Glatza, Ole Pless

Nanoscale· December 2021

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Neuronal metabotropic glutamate receptor 8 protects against neurodegeneration in CNS inflammation.
Marcel S Woo, Friederike Ufer, Nicola Rothammer, Giovanni Di Liberto, Lars Binkle, Ole Pless

J Exp Med· May 2021

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An automated and high-throughput-screening compatible pluripotent stem cell-based test platform for developmental and reproductive toxicity assessment of small molecule compounds.
Gesa Witt, Oliver Keminer, Jennifer Leu, Rashmi Tandon, Ina Meiser, Ole Pless

Cell Biol Toxicol· April 2021

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Enhancing mitochondrial activity in neurons protects against neurodegeneration in a mouse model of multiple sclerosis.
Sina C Rosenkranz, Artem A Shaposhnykov, Simone Träger, Jan Broder Engler, Maarten E Witte, Ole Pless

Elife· February 2021

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Human iPSC-Derived Blood-Brain Barrier Models: Valuable Tools for Preclinical Drug Discovery and Development?
Antje Appelt-Menzel, Sabrina Oerter, Sanjana Mathew, Undine Haferkamp, Carla Hartmann, Ole Pless

Curr Protoc Stem Cell Biol· December 2020

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Lipid Mediator Profiles Predict Response to Therapy with an Oral Frankincense Extract in Relapsing-Remitting Multiple Sclerosis.
Klarissa Hanja Stürner, Oliver Werz, Andreas Koeberle, Markus Otto, Ole Pless

Sci Rep· May 2020

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