Publications by authors named "Olivier Rene"

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Cyanotriazoles are selective topoisomerase II poisons that rapidly cure trypanosome infections.
Srinivasa P S Rao, Matthew K Gould, Jonas Noeske, Manuel Saldivia, Rajiv S Jumani

Science· June 2023

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Verification of exposure to chemical warfare agents through analysis of persistent biomarkers in plants.
Mirjam de Bruin-Hoegée, Latifa Lamriti, Jan P Langenberg, René C M Olivier, Lai Fun Chau

Anal Methods· January 2023

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Discovery of Novel Quinoline-Based Proteasome Inhibitors for Human African Trypanosomiasis (HAT).
Dennis C Koester, Vanessa M Marx, Sarah Williams, Jan Jiricek, Maxime Dauphinais, Jean-Rene Galarneau

J Med Chem· September 2022

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Discovery of oxa-sultams as RORc inverse agonists showing reduced lipophilicity, improved selectivity and favorable ADME properties.
Olivier René, Benjamin P Fauber, Adrian Barnard, Kerry Chapman, Yuzhong Deng

Bioorg Med Chem Lett· September 2016

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ANKRD26 normocytic thrombocytopenia: a family report.
Anne Vincenot, Marie-Françoise Hurtaud-Roux, Olivier René, Sylvie Binard, Odile Fenneteau

Ann Biol Clin (Paris)· June 2016

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Palladium-Catalyzed Ring Expansion of Spirocyclopropanes to Form Caprolactams and Azepanes.
Olivier René, Iain A Stepek, Alberto Gobbi, Benjamin P Fauber, Simon Gaines

J Org Chem· October 2015

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Discovery of 1-{4-[3-fluoro-4-((3s,6r)-3-methyl-1,1-dioxo-6-phenyl-[1,2]thiazinan-2-ylmethyl)-phenyl]-piperazin-1-yl}-ethanone (GNE-3500): a potent, selective, and orally bioavailable retinoic acid receptor-related orphan receptor C (RORc or RORγ) inverse agonist.
Benjamin P Fauber, Olivier René, Yuzhong Deng, Jason DeVoss, Céline Eidenschenk

J Med Chem· July 2015

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Herpes Viral Origin of the Parsonage-Turner Syndrome: Highlighting of Serological Immune Anti-Herpes Deficiency Cured by Anti-Herpes Therapy.
Jacqueline Le Goaster, Patrice Bourée, Charles Ifergan, Frederic Tangy, René Olivier

Case Rep Neurol· June 2015

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Minor Structural Change to Tertiary Sulfonamide RORc Ligands Led to Opposite Mechanisms of Action.
Olivier René, Benjamin P Fauber, Gladys de Leon Boenig, Brenda Burton, Céline Eidenschenk

ACS Med Chem Lett· March 2015

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Experimental and Computational Studies of the Diastereoselective Alkylations of 3-Substituted γ-Sultams.
Benjamin P Fauber, Kyle Clagg, Paul Gibbons, Olivier René

J Org Chem· January 2015

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A reversed sulfonamide series of selective RORc inverse agonists.
Monique B van Niel, Benjamin P Fauber, Matthew Cartwright, Simon Gaines, Jonathan C Killen

Bioorg Med Chem Lett· December 2014

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Reduction in lipophilicity improved the solubility, plasma-protein binding, and permeability of tertiary sulfonamide RORc inverse agonists.
Benjamin P Fauber, Olivier René, Gladys de Leon Boenig, Brenda Burton, Yuzhong Deng

Bioorg Med Chem Lett· August 2014

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Palladium-catalyzed α-arylation of sultams with aryl and heteroaryl iodides.
Olivier René, Benjamin P Fauber, Sushant Malhotra, Herbert Yajima

Org Lett· July 2014

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Identification of tertiary sulfonamides as RORc inverse agonists.
Benjamin P Fauber, Olivier René, Brenda Burton, Christine Everett, Alberto Gobbi

Bioorg Med Chem Lett· May 2014

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Structure-based design of substituted hexafluoroisopropanol-arylsulfonamides as modulators of RORc.
Benjamin P Fauber, Gladys de Leon Boenig, Brenda Burton, Céline Eidenschenk, Christine Everett

Bioorg Med Chem Lett· December 2013

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Late steps of ribosome assembly in E. coli are sensitive to a severe heat stress but are assisted by the HSP70 chaperone machine.
Olivier René, Jean-Hervé Alix

Nucleic Acids Res· March 2011

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Room-temperature direct arylation of polyfluorinated arenes under biphasic conditions.
Olivier René, Keith Fagnou

Org Lett· May 2010

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Domino palladium-catalyzed Heck-intermolecular direct arylation reactions.
Olivier René, David Lapointe, Keith Fagnou

Org Lett· October 2009

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Mechanism and regioselectivity of the cycloaddition of thiones derived from Meldrum's acid, malonates, or other dicarbonyls.
Stéphane Perreault, Maude Poirier, Pascal Léveillé, Olivier René, Pascal Joly

J Org Chem· October 2008

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