Publications by authors named "Olof Radmark"

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Animal models in leukotriene research: Current insights into complex pathways and therapeutic intervention.
Tarvi Teder, Olof Rådmark, Jesper Z Haeggström, Helike Lõhelaid

Pharmacol Ther· December 2025

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LC-MS/MS and high-spatial single-cell MSI reveal selective downregulation of PC(16:0_16:0) and PC(18:0_18:1) due to mPGES-1 knockdown in hormone-resistant prostate cancer cell line.
Mst Sayela Afroz, Shuhei Aramaki, Md Muedur Rahman, Maxime Dubail, Zhang Chi

Anal Bioanal Chem· December 2025

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Coactosin-Like Protein Reduces Prostaglandin D Production in Alveolar Macrophages and Alleviates Allergic Airway Inflammation.
Li-Long Pan, Zhengnan Ren, Binbin Li, Wenjie Liang, Yang Luo

Adv Sci (Weinh)· September 2025

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Formation of eicosanoids and other oxylipins in human macrophages.
Olof Radmark

Biochem Pharmacol· October 2022

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Human 5-lipoxygenase regulates transcription by association to euchromatin.
Marius Kreiß, Julia H Oberlis, Sabine Seuter, Iris Bischoff-Kont, Duran Sürün

Biochem Pharmacol· September 2022

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Modulation of microRNA processing by 5-lipoxygenase.
Stella Uebbing, Marius Kreiß, Friederike Scholl, Ann-Kathrin Häfner, Duran Sürün

FASEB J· February 2021

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Dicer up-regulation by inhibition of specific proteolysis in differentiating monocytic cells.
Devaraj Basavarajappa, Stella Uebbing, Marius Kreiss, Ana Lukic, Beatrix Suess

Proc Natl Acad Sci U S A· April 2020

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Exosomes and cells from lung cancer pleural exudates transform LTC4 to LTD4, promoting cell migration and survival via CysLT1.
Ana Lukic, Casper J E Wahlund, Cristina Gómez, Daniel Brodin, Bengt Samuelsson

Cancer Lett· March 2019

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GM-CSF- and M-CSF-primed macrophages present similar resolving but distinct inflammatory lipid mediator signatures.
Ana Lukic, Pia Larssen, Alexander Fauland, Bengt Samuelsson, Craig E Wheelock, Olof Radmark

FASEB J· October 2017

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Modulation of leukotriene signaling inhibiting cell growth in chronic myeloid leukemia.
Elham Yektaei-Karin, Ana Zovko, Anders Nilsson, Barbro Näsman-Glaser, Lena Kanter

Leuk Lymphoma· August 2017

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Investigation of calcium-dependent activity and conformational dynamics of zebra fish 12-lipoxygenase.
Monica Mittal, Mahmudul Hasan, Navisraj Balagunaseelan, Alexander Fauland, Craig Wheelock

Biochim Biophys Acta Gen Subj· August 2017

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Androgen-mediated sex bias impairs efficiency of leukotriene biosynthesis inhibitors in males.
Simona Pace, Carlo Pergola, Friederike Dehm, Antonietta Rossi, Jana Gerstmeier

J Clin Invest· August 2017

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Age dictates a steroid-resistant cascade of Wnt5a, transglutaminase 2, and leukotrienes in inflamed airways.
Katharina Dietz, Marta de Los Reyes Jiménez, Eva S Gollwitzer, Adam M Chaker, Ulrich M Zissler

J Allergy Clin Immunol· April 2017

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Pulmonary sarcoidosis is associated with exosomal vitamin D-binding protein and inflammatory molecules.
Maria-Jose Martinez-Bravo, Casper J E Wahlund, Khaleda Rahman Qazi, Robert Moulder, Ana Lukic

J Allergy Clin Immunol· April 2017

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Pulmonary epithelial cancer cells and their exosomes metabolize myeloid cell-derived leukotriene C4 to leukotriene D4.
Ana Lukic, Jie Ji, Helena Idborg, Bengt Samuelsson, Lena Palmberg

J Lipid Res· September 2016

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Structural and Functional Analysis of Calcium Ion Mediated Binding of 5-Lipoxygenase to Nanodiscs.
Ramakrishnan B Kumar, Lin Zhu, Helena Idborg, Olof Rådmark, Per-Johan Jakobsson

PLoS One· August 2016

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Kinetic investigation of human 5-lipoxygenase with arachidonic acid.
Monica Mittal, Ramakrishnan B Kumar, Navisraj Balagunaseelan, Mats Hamberg, Caroline Jegerschöld

Bioorg Med Chem Lett· August 2016

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Linking microsomal prostaglandin E Synthase-1/PGE-2 pathway with miR-15a and -186 expression: Novel mechanism of VEGF modulation in prostate cancer.
Erika Terzuoli, Sandra Donnini, Federica Finetti, Gabriella Nesi, Donata Villari, Olof Radmark

Oncotarget· July 2016

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Time-resolved in situ assembly of the leukotriene-synthetic 5-lipoxygenase/5-lipoxygenase-activating protein complex in blood leukocytes.
Jana Gerstmeier, Christina Weinigel, Silke Rummler, Olof Rådmark, Oliver Werz

FASEB J· January 2016

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Lipoxin and resolvin biosynthesis is dependent on 5-lipoxygenase activating protein.
Christoph Lehmann, Julia Homann, Ann-Katrin Ball, René Blöcher, Thea K Kleinschmidt

FASEB J· December 2015

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Phosphorylation of serine 523 on 5-lipoxygenase in human B lymphocytes.
Yilmaz Mahshid, Stavroula Markoutsa, Vildan Dincbas-Renqvist, Duran Sürün, Birger Christensson

Prostaglandins Leukot Essent Fatty Acids· September 2015

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mPGES-1 in prostate cancer controls stemness and amplifies epidermal growth factor receptor-driven oncogenicity.
Federica Finetti, Erika Terzuoli, Antonio Giachetti, Raffaella Santi, Donata Villari, Olof Radmark

Endocr Relat Cancer· August 2015

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5-Lipoxygenase, a key enzyme for leukotriene biosynthesis in health and disease.
Olof Rådmark, Oliver Werz, Dieter Steinhilber, Bengt Samuelsson

Biochim Biophys Acta· April 2015

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Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice.
Jose Pedro Friedmann Angeli, Manuela Schneider, Bettina Proneth, Yulia Y Tyurina, Vladimir A Tyurin

Nat Cell Biol· December 2014

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Stabilisation and characterisation of the isolated regulatory domain of human 5-lipoxygenase.
Mirjam Schröder, Ann-Kathrin Häfner, Bettina Hofmann, Olof Rådmark, Franz Tumulka

Biochim Biophys Acta· October 2014

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