Publications by authors named "Orf Mook"

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Variants Can Associate with Non-Syndromic Congenital Heart Disease without Aortopathy.
Manal Alaamery, Nour Albesher, Fahad Alhabshan, Phil Barnett, Mohamed Salim Kabbani, Olaf R F Mook

J Cardiovasc Dev Dis· November 2023

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Clinicobiological characteristics and treatment efficacy of novel agents in chronic lymphocytic leukemia with IGLV3-21.
Paul J Hengeveld, Y Emre Ertem, Julie M N Dubois, Clemens H M Mellink, Anne-Marie van der Kevie-Kersemaekers, Olaf R F Mook

Leukemia· July 2022

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Large next-generation sequencing gene panels in genetic heart disease: challenges in clinical practice.
I Christiaans, O R F Mook, M Alders, H Bikker, R H Lekanne Dit Deprez

Neth Heart J· June 2019

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Large next-generation sequencing gene panels in genetic heart disease: yield of pathogenic variants and variants of unknown significance.
F H M van Lint, O R F Mook, M Alders, H Bikker, R H Lekanne Dit Deprez

Neth Heart J· June 2019

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Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression.
Jana Naue, Huub C J Hoefsloot, Olaf R F Mook, Laura Rijlaarsdam-Hoekstra, Marloes C H van der Zwalm

Forensic Sci Int Genet· November 2017

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Targeted sequence capture and GS-FLX Titanium sequencing of 23 hypertrophic and dilated cardiomyopathy genes: implementation into diagnostics.
Olaf R F Mook, Martin A Haagmans, Jean-François Soucy, Judith B A van de Meerakker, Frank Baas

J Med Genet· September 2013

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A novel alpha-tropomyosin mutation associates with dilated and non-compaction cardiomyopathy and diminishes actin binding.
Judith B A van de Meerakker, Imke Christiaans, Phil Barnett, Ronald H Lekanne Deprez, Aho Ilgun, Olaf R F Mook

Biochim Biophys Acta· April 2013

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In vivo efficacy and off-target effects of locked nucleic acid (LNA) and unlocked nucleic acid (UNA) modified siRNA and small internally segmented interfering RNA (sisiRNA) in mice bearing human tumor xenografts.
Orf Mook, Jeroen Vreijling, Suzy L Wengel, Jesper Wengel, Chuanzheng Zhou

Artif DNA PNA XNA· July 2010

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Filling the gap in LNA antisense oligo gapmers: the effects of unlocked nucleic acid (UNA) and 4'-C-hydroxymethyl-DNA modifications on RNase H recruitment and efficacy of an LNA gapmer.
Kees Fluiter, Olaf R F Mook, Jeroen Vreijling, Niels Langkjaer, Torben Højland

Mol Biosyst· August 2009

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Allele-specific cancer cell killing in vitro and in vivo targeting a single-nucleotide polymorphism in POLR2A.
O R F Mook, F Baas, M B de Wissel, K Fluiter

Cancer Gene Ther· June 2009

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Changes in gene expression of granulocytes during in vivo granulocyte colony-stimulating factor/dexamethasone mobilization for transfusion purposes.
Agata Drewniak, Bram J van Raam, Judy Geissler, Anton T J Tool, Olaf R F Mook

Blood· June 2009

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The therapeutic potential of LNA-modified siRNAs: reduction of off-target effects by chemical modification of the siRNA sequence.
Kees Fluiter, Olaf R F Mook, Frank Baas

Methods Mol Biol· April 2009

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Interactions between colon cancer cells and hepatocytes in rats in relation to metastasis.
O R F Mook, J van Marle, R Jonges, H Vreeling-Sindelárová, W M Frederiks

J Cell Mol Med· October 2008

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Noninvasive magnetic resonance imaging of the development of individual colon cancer tumors in rat liver.
Olaf R F Mook, Ard Jonker, Aart C Strang, Andor Veltien, Giulio Gambarota

Biotechniques· April 2008

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The role of gelatinases in colorectal cancer progression and metastasis.
Olaf R F Mook, Wilma M Frederiks, Cornelis J F Van Noorden

Biochim Biophys Acta· December 2004

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Metabolic mapping of proteinase activity with emphasis on in situ zymography of gelatinases: review and protocols.
Wilma M Frederiks, Olaf R F Mook

J Histochem Cytochem· June 2004

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Visualization of early events in tumor formation of eGFP-transfected rat colon cancer cells in liver.
Olaf R F Mook, Jan Van Marle, Heleen Vreeling-Sindelárová, Remmet Jonges, Wilma M Frederiks

Hepatology· August 2003

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In situ localization of gelatinolytic activity in the extracellular matrix of metastases of colon cancer in rat liver using quenched fluorogenic DQ-gelatin.
Olaf R F Mook, Claudia Van Overbeek, Eleonora G Ackema, Febe Van Maldegem, Wilma M Frederiks

J Histochem Cytochem· June 2003

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