Publications by authors named "Ovini Amarasinghe"

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Targeting LMO2-induced autocrine FLT3 signaling to overcome chemoresistance in early T-cell precursor acute lymphoblastic leukemia.
Cedric S Tremblay, Jesslyn Saw, Feng Yan, Jacqueline A Boyle, Ovini Amarasinghe

Leukemia· March 2025

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Discovery and evaluation of novel SHIP-1 inhibitors.
Jinmin Miao, Jianping Lin, Jiajun Dong, Ovini Amarasinghe, Emily R Mason

Bioorg Med Chem· November 2024

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SHIP1 therapeutic target enablement: Identification and evaluation of inhibitors for the treatment of late-onset Alzheimer's disease.
Cynthia D Jesudason, Emily R Mason, Shaoyou Chu, Adrian L Oblak, June Javens-Wolfe, Ovini Amarasinghe

Alzheimers Dement (N Y)· November 2023

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PTP4A2 promotes lysophagy by dephosphorylation of VCP/p97 at Tyr805.
Yunpeng Bai, Guimei Yu, Hong-Ming Zhou, Ovini Amarasinghe, Yuan Zhou

Autophagy· May 2023

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Cryo-electron microscopy structures of VCP/p97 reveal a new mechanism of oligomerization regulation.
Guimei Yu, Yunpeng Bai, Kunpeng Li, Ovini Amarasinghe, Wen Jiang

iScience· November 2021

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Mechanism of PRL2 phosphatase-mediated PTEN degradation and tumorigenesis.
Qinglin Li, Yunpeng Bai, L Tiffany Lyle, Guimei Yu, Ovini Amarasinghe

Proc Natl Acad Sci U S A· August 2020

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