Publications by authors named "Padmakumar Narayanan"

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Cellular immune changes during severe antisense oligonucleotide-associated thrombocytopenia in a nonhuman primate model.
Sheena Gupta, Lijiang Shen, Scott P Henry, Nima Aghaeepour, Padmakumar Narayanan

J Immunol· April 2025

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Complement C3d/C4d Deposition on Platelets Correlates with 2'-O-Methoxyethyl Antisense Oligonucleotide-Induced Thrombocytopenia in Monkeys.
Lijiang Shen, Andrea Wong, Satoru Oneda, Brian R Curtis, Joe Schroeder, Padmakumar Narayanan

Nucleic Acid Ther· June 2023

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Sequence-specific 2'-O-methoxyethyl antisense oligonucleotides activate human platelets through glycoprotein VI, triggering formation of platelet-leukocyte aggregates.
Martina H Lundberg Slingsby, Prakrith Vijey, I-Ting Tsai, Harvey Roweth, Genevieve Couldwell, Padmakumar Narayanan

Haematologica· February 2022

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The atlas of RNase H antisense oligonucleotide distribution and activity in the CNS of rodents and non-human primates following central administration.
Paymaan Jafar-Nejad, Berit Powers, Armand Soriano, Hien Zhao, Daniel A Norris, Padmakumar Narayanan

Nucleic Acids Res· January 2021

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Underlying Immune Disorder May Predispose Some Transthyretin Amyloidosis Subjects to Inotersen-Mediated Thrombocytopenia.
PadmaKumar Narayanan, Brian R Curtis, Lijiang Shen, Eugene Schneider, Joseph A Tami

Nucleic Acid Ther· April 2020

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Investigation into the Mechanism(s) That Leads to Platelet Decreases in Cynomolgus Monkeys During Administration of ISIS 104838, a 2'-MOE-Modified Antisense Oligonucleotide.
Padmakumar Narayanan, Lijiang Shen, Brian R Curtis, Mario A Bourdon, John P Nolan

Toxicol Sci· August 2018

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Assessment of the Effects of 2'-Methoxyethyl Antisense Oligonucleotides on Platelet Count in Cynomolgus Nonhuman Primates.
Scott P Henry, Padmakumar Narayanan, Lijiang Shen, Sanjay Bhanot, Husam S Younis

Nucleic Acid Ther· August 2017

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