Publications by authors named "Padraig Doolan"

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Serum-Free and Protein-Free Media for the Cultivation of Recombinant Chinese Hamster Ovary (CHO) Cell Lines.
Berta Capella Roca, Justine Meiller, Padraig Doolan, Martin Clynes

Methods Mol Biol· October 2024

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Genomic Profiling and Functional Analysis of let-7c miRNA-mRNA Interactions Identify to Be Involved in Invasion and Progression of Pancreatic Cancer.
Shannon R Nelson, Sandra Roche, Maura Cotter, Pablo Anton Garcia, Daniela Reitmeier, Padraig Doolan

J Oncol· December 2020

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Altered gene expression in CHO cells following polyamine starvation.
Berta Capella Roca, Padraig Doolan, Niall Barron, Fiona O'Neill, Martin Clynes

Biotechnol Lett· June 2020

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Investigation and circumvention of transfection inhibition by ferric ammonium citrate in serum-free media for Chinese hamster ovary cells.
Berta Capella Roca, Nga T Lao, Martin Clynes, Padraig Doolan

Biotechnol Prog· May 2020

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An arginase-based system for selection of transfected CHO cells without the use of toxic chemicals.
Berta Capella Roca, Nga Lao, Niall Barron, Padraig Doolan, Martin Clynes

J Biol Chem· December 2019

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Zinc supplementation increases protein titer of recombinant CHO cells.
Berta Capella Roca, Antonio Alarcón Miguez, Joanne Keenan, Srinivas Suda, Niall Barron, Padraig Doolan

Cytotechnology· October 2019

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Acute exposure to organic and inorganic sources of copper: Differential response in intestinal cell lines.
Joanne Keenan, Finbarr O'Sullivan, Michael Henry, Laura Breen, Padraig Doolan

Food Sci Nutr· November 2018

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Parallel mRNA, proteomics and miRNA expression analysis in cell line models of the intestine.
Finbarr O'Sullivan, Joanne Keenan, Sinead Aherne, Fiona O'Neill, Colin Clarke, Padraig Doolan

World J Gastroenterol· November 2017

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Comparative transcriptomic analysis of cultivated limbal epithelium and donor corneal tissue reveals altered wound healing gene expression.
Clair Gallagher, Colin Clarke, Sinéad T Aherne, Kishore R Katikireddy, Padraig Doolan

Invest Ophthalmol Vis Sci· August 2014

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MiR-7 triggers cell cycle arrest at the G1/S transition by targeting multiple genes including Skp2 and Psme3.
Noelia Sanchez, Mark Gallagher, Nga Lao, Clair Gallagher, Colin Clarke, Padraig Doolan

PLoS One· January 2014

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Correlating transcriptional networks to breast cancer survival: a large-scale coexpression analysis.
Colin Clarke, Stephen F Madden, Padraig Doolan, Sinead T Aherne, Helena Joyce

Carcinogenesis· October 2013

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Transcriptomic analysis of clonal growth rate variation during CHO cell line development.
Padraig Doolan, Colin Clarke, Paula Kinsella, Laura Breen, Paula Meleady

J Biotechnol· July 2013

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A gene expression profile indicative of early stage HER2 targeted therapy response.
Fiona O'Neill, Stephen F Madden, Martin Clynes, John Crown, Padraig Doolan

Mol Cancer· July 2013

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Integrated miRNA, mRNA and protein expression analysis reveals the role of post-transcriptional regulation in controlling CHO cell growth rate.
Colin Clarke, Michael Henry, Padraig Doolan, Shane Kelly, Sinead Aherne

BMC Genomics· November 2012

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CGCDB: a web-based resource for the investigation of gene coexpression in CHO cell culture.
Colin Clarke, Padraig Doolan, Niall Barron, Paula Meleady, Stephen F Madden

Biotechnol Bioeng· June 2012

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Utilization and evaluation of CHO-specific sequence databases for mass spectrometry based proteomics.
Paula Meleady, Raimund Hoffrogge, Michael Henry, Oliver Rupp, Juan Hernandez Bort, Padraig Doolan

Biotechnol Bioeng· June 2012

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Gene expression changes as markers of early lapatinib response in a panel of breast cancer cell lines.
Fiona O'Neill, Stephen F Madden, Sinead T Aherne, Martin Clynes, John Crown, Padraig Doolan

Mol Cancer· June 2012

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MAGE-D4B is a novel marker of poor prognosis and potential therapeutic target involved in breast cancer tumorigenesis.
Serena Germano, Susan Kennedy, Sweta Rani, Grainne Gleeson, Martin Clynes, Padraig Doolan

Int J Cancer· May 2012

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Microarray expression profiling identifies genes regulating sustained cell specific productivity (S-Qp) in CHO K1 production cell lines.
Padraig Doolan, Niall Barron, Paula Kinsella, Colin Clarke, Paula Meleady

Biotechnol J· April 2012

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Olfactomedin III expression contributes to anoikis-resistance in clonal variants of a human lung squamous carcinoma cell line.
Joanne Keenan, Helena Joyce, Sinead Aherne, Shirley O'Dea, Padraig Doolan

Exp Cell Res· March 2012

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Characterization and response of newly developed high-grade glioma cultures to the tyrosine kinase inhibitors, erlotinib, gefitinib and imatinib.
Paula Kinsella, Rachel Howley, Padraig Doolan, Colin Clarke, Stephen F Madden

Exp Cell Res· March 2012

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Development and characterization of a Chinese hamster ovary cell-specific oligonucleotide microarray.
Mark Melville, Padraig Doolan, William Mounts, Niall Barron, Louane Hann

Biotechnol Lett· September 2011

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Large scale microarray profiling and coexpression network analysis of CHO cells identifies transcriptional modules associated with growth and productivity.
Colin Clarke, Padraig Doolan, Niall Barron, Paula Meleady, Finbarr O'Sullivan

J Biotechnol· September 2011

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Sustained productivity in recombinant Chinese hamster ovary (CHO) cell lines: proteome analysis of the molecular basis for a process-related phenotype.
Paula Meleady, Padraig Doolan, Michael Henry, Niall Barron, Joanne Keenan

BMC Biotechnol· July 2011

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2D-DIGE analysis of phospho-enriched fractions from dasatinib-treated melanoma cell lines.
Alex J Eustace, Paul Dowling, Michael Henry, Padraig Doolan, Paula Meleady

J Proteomics· April 2011

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