Publications by authors named "Paritha Arumugam"

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Lentiviral gene therapy with reduced-intensity conditioning for sickle cell disease: a phase 1/2 trial.
Michael Grimley, Stella M Davies, Archana Shrestha, Amy Shova, Monika Asnani, Paritha I Arumugam

Nat Med· July 2025

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A toxicology study of complementation and pulmonary macrophage transplantation therapy of hereditary PAP in mice.
Paritha Arumugam, Brenna C Carey, Kathryn A Wikenheiser-Brokamp, Jeffrey Krischer, Matthew Wessendarp

Mol Ther Methods Clin Dev· June 2024

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A dried blood spot test for diagnosis of autoimmune pulmonary alveolar proteinosis.
Brenna Carey, Claudia Chalk, Jennifer Stock, Andrea Toth, Maria Klingler, Paritha Arumugam

J Immunol Methods· December 2022

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A murine model of hereditary pulmonary alveolar proteinosis caused by homozygous gene disruption.
Kenjiro Shima, Paritha Arumugam, Anthony Sallese, Yuko Horio, Yan Ma

Am J Physiol Lung Cell Mol Physiol· March 2022

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Role of GM-CSF in regulating metabolism and mitochondrial functions critical to macrophage proliferation.
Matthew Wessendarp, Miki Watanabe-Chailland, Serena Liu, Traci Stankiewicz, Yan Ma, Paritha Arumugam

Mitochondrion· January 2022

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Thrombin-PAR1 signaling in pancreatic cancer promotes an immunosuppressive microenvironment.
Patrick G Schweickert, Yi Yang, Emily E White, Gregory M Cresswell, Bennett D Elzey, Paritha Arumugam

J Thromb Haemost· January 2021

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Neutrophil extracellular traps activate IL-8 and IL-1 expression in human bronchial epithelia.
Kristin M Hudock, Margaret S Collins, Michelle Imbrogno, John Snowball, Elizabeth L Kramer, Paritha Arumugam

Am J Physiol Lung Cell Mol Physiol· July 2020

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FOXM1 nuclear transcription factor translocates into mitochondria and inhibits oxidative phosphorylation.
Markaisa Black, Paritha Arumugam, Samriddhi Shukla, Arun Pradhan, Vladimir Ustiyan

Mol Biol Cell· June 2020

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Long-Term Safety and Efficacy of Gene-Pulmonary Macrophage Transplantation Therapy of PAP in Csf2ra Mice.
Paritha Arumugam, Takuji Suzuki, Kenjiro Shima, Cormac McCarthy, Anthony Sallese

Mol Ther· September 2019

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Elimination of the fibrinogen integrin αβ-binding motif improves renal pathology in mice with sickle cell anemia.
Md Nasimuzzaman, Paritha I Arumugam, Eric S Mullins, Jeanne M James, Katherine VandenHeuvel

Blood Adv· May 2019

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Statin as a novel pharmacotherapy of pulmonary alveolar proteinosis.
Cormac McCarthy, Elinor Lee, James P Bridges, Anthony Sallese, Takuji Suzuki, Paritha Arumugam

Nat Commun· August 2018

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Foamy Virus Vector Carries a Strong Insulator in Its Long Terminal Repeat Which Reduces Its Genotoxic Potential.
Michael Aaron Goodman, Paritha Arumugam, Devin Marie Pillis, Anastacia Loberg, Mohammed Nasimuzzaman

J Virol· January 2018

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Function and Safety of Lentivirus-Mediated Gene Transfer for CSF2RA-Deficiency.
Miriam Hetzel, Takuji Suzuki, Anna Rafiei Hashtchin, Paritha Arumugam, Brenna Carey

Hum Gene Ther Methods· December 2017

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Targeting cholesterol homeostasis in lung diseases.
Anthony Sallese, Takuji Suzuki, Cormac McCarthy, James Bridges, Alyssa Filuta, Paritha Arumugam

Sci Rep· August 2017

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High Level of Perforin Expression Is Required for Effective Correction of Hemophagocytic Lymphohistiocytosis.
Swati Tiwari, Adrianne Hontz, Catherine E Terrell, Paritha Arumugam, Marlene Carmo

Hum Gene Ther· October 2016

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Placenta growth factor augments airway hyperresponsiveness via leukotrienes and IL-13.
Marthe-Sandrine Eiymo Mwa Mpollo, Eric B Brandt, Shiva Kumar Shanmukhappa, Paritha I Arumugam, Swati Tiwari

J Clin Invest· February 2016

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Genetic diminution of circulating prothrombin ameliorates multiorgan pathologies in sickle cell disease mice.
Paritha I Arumugam, Eric S Mullins, Shiva Kumar Shanmukhappa, Brett P Monia, Anastacia Loberg

Blood· October 2015

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Pigtailed macaques as a model to study long-term safety of lentivirus vector-mediated gene therapy for hemoglobinopathies.
Hans-Peter Kiem, Paritha I Arumugam, Christopher R Burtner, Catherine F Fox, Brian C Beard

Mol Ther Methods Clin Dev· June 2015

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Perforin gene transfer into hematopoietic stem cells improves immune dysregulation in murine models of perforin deficiency.
Marlene Carmo, Kimberly A Risma, Paritha Arumugam, Swati Tiwari, Adrianne E Hontz

Mol Ther· April 2015

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Pulmonary macrophage transplantation therapy.
Takuji Suzuki, Paritha Arumugam, Takuro Sakagami, Nico Lachmann, Claudia Chalk

Nature· October 2014

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RhoA GTPase controls cytokinesis and programmed necrosis of hematopoietic progenitors.
Xuan Zhou, Maria Carolina Florian, Paritha Arumugam, Xiaoyi Chen, Jose A Cancelas

J Exp Med· October 2013

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Genetic therapy for beta-thalassemia: from the bench to the bedside.
Paritha Arumugam, Punam Malik

Hematology Am Soc Hematol Educ Program· April 2011

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Genotoxic potential of lineage-specific lentivirus vectors carrying the beta-globin locus control region.
Paritha I Arumugam, Tomoyasu Higashimoto, Fabrizia Urbinati, Ute Modlich, Shawna Nestheide

Mol Ther· November 2009

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Mechanism of reduction in titers from lentivirus vectors carrying large inserts in the 3'LTR.
Fabrizia Urbinati, Paritha Arumugam, Tomoyasu Higashimoto, Anil Perumbeti, Kyle Mitts

Mol Ther· September 2009

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The 3' region of the chicken hypersensitive site-4 insulator has properties similar to its core and is required for full insulator activity.
Paritha I Arumugam, Fabrizia Urbinati, Chinavenmeni S Velu, Tomoyasu Higashimoto, H Leighton Grimes

PLoS One· September 2009

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