Publications by authors named "Pascal Merchiers"

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Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1 T lymphocyte niches through a feed-forward loop.
Yichao Hua, Gerlanda Vella, Florian Rambow, Elizabeth Allen, Asier Antoranz Martinez, Pascal Merchiers

Cancer Cell· January 2023

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Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1 T lymphocyte niches through a feed-forward loop.
Yichao Hua, Gerlanda Vella, Florian Rambow, Elizabeth Allen, Asier Antoranz Martinez, Pascal Merchiers

Cancer Cell· December 2022

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Therapeutic depletion of CCR8 tumor-infiltrating regulatory T cells elicits antitumor immunity and synergizes with anti-PD-1 therapy.
Helena Van Damme, Bruno Dombrecht, Máté Kiss, Heleen Roose, Elizabeth Allen, Pascal Merchiers

J Immunother Cancer· February 2021

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CD25-T-depleting antibodies preserving IL-2 signaling on effector T cells enhance effector activation and antitumor immunity.
Isabelle Solomon, Maria Amann, Anne Goubier, Frederick Arce Vargas, Dimitrios Zervas, Pascal Merchiers

Nat Cancer· December 2020

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Llama-derived single variable domains (nanobodies) directed against chemokine receptor CXCR7 reduce head and neck cancer cell growth in vivo.
David Maussang, Azra Mujić-Delić, Francis J Descamps, Catelijne Stortelers, Peter Vanlandschoot, Pascal Merchiers

J Biol Chem· October 2013

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Enhancement of polymeric immunoglobulin receptor transcytosis by biparatopic VHH.
Chris D Emmerson, Els J van der Vlist, Myrthe R Braam, Peter Vanlandschoot, Pascal Merchiers

PLoS One· February 2012

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Peroxisome proliferator-activated receptor gamma enhances the activity of an insulin degrading enzyme-like metalloprotease for amyloid-beta clearance.
Ira Espuny-Camacho, Diana Dominguez, Pascal Merchiers, Luc Van Rompaey, Dennis Selkoe

J Alzheimers Dis· October 2010

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Pathological Hallmarks, Clinical Parallels, and Value for Drug Testing in Alzheimer's Disease of the APP[V717I] London Transgenic Mouse Model.
An Tanghe, Annelies Termont, Pascal Merchiers, Stephan Schilling, Hans-Ulrich Demuth

Int J Alzheimers Dis· September 2010

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The orphan G protein-coupled receptor 3 modulates amyloid-beta peptide generation in neurons.
Amantha Thathiah, Kurt Spittaels, Marcel Hoffmann, Mik Staes, Adrian Cohen, Pascal Merchiers

Science· February 2009

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Peroxisome-proliferator-activated receptor gamma induces a clearance mechanism for the amyloid-beta peptide.
Ira Espuny Camacho, Lutgarde Serneels, Kurt Spittaels, Pascal Merchiers, Diana Dominguez

J Neurosci· December 2004

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Presenilins mutated at Asp-257 or Asp-385 restore Pen-2 expression and Nicastrin glycosylation but remain catalytically inactive in the absence of wild type Presenilin.
Omar Nyabi, Mostafa Bentahir, Katrien Horré, An Herreman, Numa Gottardi-Littell, Pascal Merchiers

J Biol Chem· October 2003

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Arrayed adenoviral expression libraries for functional screening.
Frits Michiels, Helmuth van Es, Luc van Rompaey, Pascal Merchiers, Bart Francken

Nat Biotechnol· November 2002

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