Publications by authors named "Pascal Therond"

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TMED10 mediates the loading of neosynthesised Sonic Hedgehog in COPII vesicles for efficient secretion and signalling.
Yonis Bare, Tamás Matusek, Sophie Vriz, Maika S Deffieu, Pascal P Thérond

Cell Mol Life Sci· August 2023

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Regulation of the collagen IV network by the basement membrane protein perlecan is crucial for squamous epithelial cell morphogenesis and organ architecture.
Raphaël Bonche, Prune Smolen, Aline Chessel, Séverine Boisivon, Sabrina Pisano

Matrix Biol· December 2022

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Microvilli-derived extracellular vesicles carry Hedgehog morphogenic signals for Drosophila wing imaginal disc development.
Ilse Hurbain, Anne-Sophie Macé, Maryse Romao, Elodie Prince, Lucie Sengmanivong

Curr Biol· January 2022

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Arf6 is necessary for senseless expression in response to wingless signalling during Drosophila wing development.
Julien Marcetteau, Tamàs Matusek, Frédéric Luton, Pascal P Thérond

Biol Open· December 2021

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Hherisomes, Hedgehog specialized recycling endosomes, are required for high level Hedgehog signaling and tissue growth.
Sandrine Pizette, Tamás Matusek, Bram Herpers, Pascal P Thérond, Catherine Rabouille

J Cell Sci· May 2021

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Two different sources of Perlecan cooperate for its function in the basement membrane of the Drosophila wing imaginal disc.
Raphaël Bonche, Aline Chessel, Séverine Boisivon, Prune Smolen, Pascal Thérond

Dev Dyn· April 2021

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The GTPase Rab8 differentially controls the long- and short-range activity of the Hedgehog morphogen gradient by regulating Hedgehog apico-basal distribution.
Tanvi Gore, Tamás Matusek, Gisela D'Angelo, Cécile Giordano, Thomas Tognacci

Development· March 2021

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Circulating Hedgehog: a fresh view of a classic morphogen.
Elodie Prince, Julien Marcetteau, Pascal P Thérond

Development· December 2020

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Functions of Wnt and Hedgehog-containing extracellular vesicles in development and disease.
Tamás Matusek, Julien Marcetteau, Pascal P Thérond

J Cell Sci· September 2020

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Functional Analysis of ESCRT-Positive Extracellular Vesicles in the Drosophila Wing Imaginal Disc.
Tamás Matusek, Pascal Thérond, Maximilian Fürthauer

Methods Mol Biol· March 2020

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Hedgehog Signaling Modulates Glial Proteostasis and Lifespan.
Andrew Rallis, Juan A Navarro, Mathias Rass, Amélie Hu, Serge Birman

Cell Rep· February 2020

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Protein association changes in the Hedgehog signaling complex mediate differential signaling strength.
Cecile Giordano, Laurent Ruel, Candice Poux, Pascal Therond

Development· December 2018

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Endocytosis of Hedgehog through dispatched regulates long-range signaling.
Gisela D'Angelo, Tamás Matusek, Sandrine Pizette, Pascal P Thérond

Dev Cell· February 2015

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The ESCRT machinery regulates the secretion and long-range activity of Hedgehog.
Tamás Matusek, Franz Wendler, Sophie Polès, Sandrine Pizette, Gisela D'Angelo

Nature· December 2014

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Switch of PKA substrates from Cubitus interruptus to Smoothened in the Hedgehog signalosome complex.
Nadia Ranieri, Pascal P Thérond, Laurent Ruel

Nat Commun· October 2014

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The mechanisms of Hedgehog signalling and its roles in development and disease.
James Briscoe, Pascal P Thérond

Nat Rev Mol Cell Biol· July 2013

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Dally and Notum regulate the switch between low and high level Hedgehog pathway signalling.
Katie L Ayers, Rana Mteirek, Alexandra Cervantes, Laurence Lavenant-Staccini, Pascal P Thérond

Development· September 2012

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A genome-wide RNAi screen identifies regulators of cholesterol-modified hedgehog secretion in Drosophila.
Reid Aikin, Alexandra Cervantes, Gisela D'Angelo, Laurent Ruel, Sandra Lacas-Gervais

PLoS One· July 2012

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Release and transportation of Hedgehog molecules.
Pascal P Thérond

Curr Opin Cell Biol· April 2012

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Distinct phosphorylations on kinesin costal-2 mediate differential hedgehog signaling strength.
Nadia Ranieri, Laurent Ruel, Armel Gallet, Sophie Raisin, Pascal P Thérond

Dev Cell· February 2012

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Evaluating Smoothened as a G-protein-coupled receptor for Hedgehog signalling.
Katie L Ayers, Pascal P Thérond

Trends Cell Biol· May 2010

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The long-range activity of Hedgehog is regulated in the apical extracellular space by the glypican Dally and the hydrolase Notum.
Katie L Ayers, Armel Gallet, Laurence Staccini-Lavenant, Pascal P Thérond

Dev Cell· April 2010

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The full-length unprocessed hedgehog protein is an active signaling molecule.
Robert Tokhunts, Samer Singh, Tehyen Chu, Gisela D'Angelo, Valerie Baubet

J Biol Chem· January 2010

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Variations in Hedgehog signaling: divergence and perpetuation in Sufu regulation of Gli.
Laurent Ruel, Pascal P Thérond

Genes Dev· August 2009

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Tow (Target of Wingless), a novel repressor of the Hedgehog pathway in Drosophila.
Katie L Ayers, Ralph Rodriguez, Armel Gallet, Laurent Ruel, Pascal Thérond

Dev Biol· May 2009

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