Publications by authors named "Pat Whiteman"

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ELTD1 is present in extracellular vesicles derived from endothelial cells as a cleaved extracellular domain which induces in vivo angiogenesis.
Helen Sheldon, Wei Zhang, Esther Bridges, Koon Hwee Ang, Salwa Lin, Pat Whiteman

J Extracell Biol· August 2022

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Development of Therapeutic Anti-JAGGED1 Antibodies for Cancer Therapy.
Massimo Masiero, Demin Li, Pat Whiteman, Carol Bentley, Jenny Greig

Mol Cancer Ther· November 2019

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Structural and functional dissection of the interplay between lipid and Notch binding by human Notch ligands.
Richard J Suckling, Boguslawa Korona, Pat Whiteman, Chandramouli Chillakuri, Laurie Holt

EMBO J· August 2017

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Non-Linear and Flexible Regions of the Human Notch1 Extracellular Domain Revealed by High-Resolution Structural Studies.
Philip C Weisshuhn, Devon Sheppard, Paul Taylor, Pat Whiteman, Susan M Lea

Structure· April 2016

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Bacterial expression and in vitro refolding of limited fragments of the Notch receptor and its ligands.
Pat Whiteman, Christina Redfield, Penny A Handford

Methods Mol Biol· March 2015

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Molecular basis for Jagged-1/Serrate ligand recognition by the Notch receptor.
Pat Whiteman, Beatriz Hernandez de Madrid, Paul Taylor, Demin Li, Rebecca Heslop

J Biol Chem· March 2013

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The CD46-Jagged1 interaction is critical for human TH1 immunity.
Gaëlle Le Friec, Devon Sheppard, Pat Whiteman, Christian M Karsten, Salley Al-Tilib Shamoun

Nat Immunol· December 2012

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Biophysical characterisation of fibulin-5 proteins associated with disease.
Ralf Schneider, Sacha A Jensen, Pat Whiteman, James S O McCullagh, Christina Redfield

J Mol Biol· August 2010

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A conserved face of the Jagged/Serrate DSL domain is involved in Notch trans-activation and cis-inhibition.
Jemima Cordle, Steven Johnson, Joyce Zi Yan Tay, Pietro Roversi, Marian B Wilkin, Pat Whiteman

Nat Struct Mol Biol· August 2008

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Cellular and molecular studies of Marfan syndrome mutations identify co-operative protein folding in the cbEGF12-13 region of fibrillin-1.
Pat Whiteman, Antony C Willis, Andrew Warner, James Brown, Christina Redfield

Hum Mol Genet· April 2007

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Fibrillin-1 misfolding and disease.
Pat Whiteman, Sarah Hutchinson, Penny A Handford

Antioxid Redox Signal· September 2006

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Structural consequences of cysteine substitutions C1977Y and C1977R in calcium-binding epidermal growth factor-like domain 30 of human fibrillin-1.
Ji Young Suk, Sacha Jensen, Aileen McGettrick, Antony C Willis, Pat Whiteman

J Biol Chem· December 2004

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Solution structure and dynamics of a calcium binding epidermal growth factor-like domain pair from the neonatal region of human fibrillin-1.
Rachel S Smallridge, Pat Whiteman, Jörn M Werner, Iain D Campbell, Penny A Handford

J Biol Chem· April 2003

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Defective secretion of recombinant fragments of fibrillin-1: implications of protein misfolding for the pathogenesis of Marfan syndrome and related disorders.
Pat Whiteman, Penny A Handford

Hum Mol Genet· April 2003

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