Publications by authors named "Patrick Berna"

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Translation of TRO40303 from myocardial infarction models to demonstration of safety and tolerance in a randomized Phase I trial.
Sophie Le Lamer, Stéphanie Paradis, Hidayat Rahmouni, Corinne Chaimbault, Magali Michaud, Patrick Berna

J Transl Med· February 2014

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Drug discovery and development for spinal muscular atrophy: lessons from screening approaches and future challenges for clinical development.
Rebecca M Pruss, Marc Giraudon-Paoli, Svetlana Morozova, Patrick Berna, Jean-Louis Abitbol

Future Med Chem· September 2010

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Olesoxime (TRO19622): A Novel Mitochondrial-Targeted Neuroprotective Compound.
Thierry Bordet, Patrick Berna, Jean-Louis Abitbol, Rebecca M Pruss

Pharmaceuticals (Basel)· January 2010

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Effects of depletion of neutrophils or macrophages on the inflammatory response induced by metalloelastase (MMP-12) in mice airways.
Soazig Nénan, Elisabeth Boichot, Jean-Michel Planquois, Patrick Berna, Simon Hitier

Eur J Pharmacol· January 2008

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Metalloelastase (MMP-12) induced inflammatory response in mice airways: effects of dexamethasone, rolipram and marimastat.
Soazig Nénan, Vincent Lagente, Jean-Michel Planquois, Simon Hitier, Patrick Berna

Eur J Pharmacol· March 2007

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Analysis of the inflammatory response induced by rhMMP-12 catalytic domain instilled in mouse airways.
Soazig Nénan, Jean-Michel Planquois, Patrick Berna, Isabelle De Mendez, Simon Hitier

Int Immunopharmacol· March 2005

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Discovery of thiadiazoles as a novel structural class of potent and selective PDE7 inhibitors. Part 1: design, synthesis and structure-activity relationship studies.
Fabrice Vergne, Patrick Bernardelli, Edwige Lorthiois, Nga Pham, Emmanuelle Proust, Bernadette Bertin, Patrick Berna

Bioorg Med Chem Lett· September 2004

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Discovery of thiadiazoles as a novel structural class of potent and selective PDE7 inhibitors. Part 2: metabolism-directed optimization studies towards orally bioavailable derivatives.
Fabrice Vergne, Patrick Bernardelli, Edwige Lorthiois, Nga Pham, Emmanuelle Proust, Patrick Berna

Bioorg Med Chem Lett· September 2004

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Spiroquinazolinones as novel, potent, and selective PDE7 inhibitors. Part 1.
Edwige Lorthiois, Patrick Bernardelli, Fabrice Vergne, Chrystelle Oliveira, Abdel-Kader Mafroud, Bernadette Bertin, Patrick Berna

Bioorg Med Chem Lett· September 2004

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Spiroquinazolinones as novel, potent, and selective PDE7 inhibitors. Part 2: Optimization of 5,8-disubstituted derivatives.
Patrick Bernardelli, Edwige Lorthiois, Fabrice Vergne, Chrystelle Oliveira, Abdel-Kader Mafroud, Bernadette Bertin, Patrick Berna

Bioorg Med Chem Lett· September 2004

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Resolution of 8-aminonaphthalene-1,3,6-trisulfonic acid-labeled glucose oligomers in polyacrylamide gel electrophoresis at low gel concentration.
Marion Cabanes-Macheteau, Andreas Chrambach, Myriam Taverna, Zsuzsanna Buzás, Patrick Berna

Electrophoresis· January 2004

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Crystal structure of the open form of dog gastric lipase in complex with a phosphonate inhibitor.
Alain Roussel, Nabil Miled, Liliane Berti-Dupuis, Mireille Rivière, Silvia Spinelli, Patrick Berna

J Biol Chem· January 2002

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