Publications by authors named "Patrick Franken"

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Enapotamab Vedotin, an AXL-Specific Antibody-Drug Conjugate, Demonstrates Antitumor Efficacy in Patient-Derived Xenograft Models of Soft Tissue Sarcoma.
Britt Van Renterghem, Agnieszka Wozniak, Patricia Garrido Castro, Patrick Franken, Nora Pencheva

Int J Mol Sci· July 2022

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Cooperative Targeting of Immunotherapy-Resistant Melanoma and Lung Cancer by an AXL-Targeting Antibody-Drug Conjugate and Immune Checkpoint Blockade.
Julia Boshuizen, Nora Pencheva, Oscar Krijgsman, Daniela D'Empaire Altimari, Patricia Garrido Castro, Patrick Franken

Cancer Res· April 2021

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The role of S100a4 (Mts1) in Apc- and Smad4-driven tumour onset and progression.
Yaser Atlasi, Rubina Noori, Ivana Marolin, Patrick Franken, Joana Brandao

Eur J Cancer· November 2016

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Secreted Phospholipases A2 Are Intestinal Stem Cell Niche Factors with Distinct Roles in Homeostasis, Inflammation, and Cancer.
Matthias Schewe, Patrick F Franken, Andrea Sacchetti, Mark Schmitt, Rosalie Joosten

Cell Stem Cell· July 2016

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Cancer stemness in Apc- vs. Apc/KRAS-driven intestinal tumorigenesis.
Mehrnaz Ghazvini, Petra Sonneveld, Andreas Kremer, Patrick Franken, Andrea Sacchetti

PLoS One· May 2014

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Cancer stemness in Wnt-driven mammary tumorigenesis.
Joana Monteiro, Claudia Gaspar, Wilfrid Richer, Patrick F Franken, Andrea Sacchetti

Carcinogenesis· January 2014

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Wnt5a promotes human colon cancer cell migration and invasion but does not augment intestinal tumorigenesis in Apc1638N mice.
Elvira R M Bakker, Asha Mooppilmadham Das, Werner Helvensteijn, Patrick F Franken, Sigrid Swagemakers

Carcinogenesis· November 2013

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Alterations in Wnt-β-catenin and Pten signalling play distinct roles in endometrial cancer initiation and progression.
Marten van der Zee, Yundan Jia, Yongyi Wang, Claudia Heijmans-Antonissen, Patricia C Ewing, Patrick Franken

J Pathol· May 2013

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Wnt signaling regulates the lineage differentiation potential of mouse embryonic stem cells through Tcf3 down-regulation.
Yaser Atlasi, Rubina Noori, Claudia Gaspar, Patrick Franken, Andrea Sacchetti

PLoS Genet· May 2013

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Paneth cells in intestinal homeostasis and tissue injury.
Sabrina Roth, Patrick Franken, Andrea Sacchetti, Andreas Kremer, Kurt Anderson

PLoS One· November 2012

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Induced Wnt5a expression perturbs embryonic outgrowth and intestinal elongation, but is well-tolerated in adult mice.
Elvira R M Bakker, Lalini Raghoebir, Patrick F Franken, Werner Helvensteijn, Léon van Gurp

Dev Biol· September 2012

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Generation and characterization of an inducible transgenic model for studying mouse esophageal biology.
Sabrina Roth, Patrick Franken, Kim Monkhorst, John Kong a San, Riccardo Fodde

BMC Dev Biol· June 2012

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β-catenin tyrosine 654 phosphorylation increases Wnt signalling and intestinal tumorigenesis.
Wendy van Veelen, Ngoc H Le, Werner Helvensteijn, Lau Blonden, Myrte Theeuwes, Patrick F Franken

Gut· September 2011

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Loss of APC function in mesenchymal cells surrounding the Müllerian duct leads to myometrial defects in adult mice.
Yongyi Wang, Yundan Jia, Patrick Franken, Ron Smits, Patricia C Ewing

Mol Cell Endocrinol· July 2011

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Leiden Open Variation Database of the MUTYH gene.
Astrid A Out, Carli M J Tops, Maartje Nielsen, Marjan M Weiss, Ivonne J H M van Minderhout, Patrick F Franken

Hum Mutat· November 2010

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Barrett's oesophageal adenocarcinoma encompasses tumour-initiating cells that do not express common cancer stem cell markers.
Brechtje A Grotenhuis, Winand N M Dinjens, Bas P L Wijnhoven, Petra Sonneveld, Andrea Sacchetti, Patrick F Franken

J Pathol· August 2010

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Progesterone inhibition of Wnt/beta-catenin signaling in normal endometrium and endometrial cancer.
Yongyi Wang, Payman Hanifi-Moghaddam, Eline E Hanekamp, Helenius J Kloosterboer, Patrick Franken

Clin Cancer Res· September 2009

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A targeted constitutive mutation in the APC tumor suppressor gene underlies mammary but not intestinal tumorigenesis.
Claudia Gaspar, Patrick Franken, Lia Molenaar, Cor Breukel, Martin van der Valk

PLoS Genet· July 2009

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Generation of a tightly regulated doxycycline-inducible model for studying mouse intestinal biology.
Sabrina Roth, Patrick Franken, Wendy van Veelen, Lau Blonden, Lalini Raghoebir

Genesis· January 2009

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Smad4 haploinsufficiency: a matter of dosage.
Paola Alberici, Claudia Gaspar, Patrick Franken, Marcin M Gorski, Ingrid de Vries

Pathogenetics· November 2008

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Cross-species comparison of human and mouse intestinal polyps reveals conserved mechanisms in adenomatous polyposis coli (APC)-driven tumorigenesis.
Claudia Gaspar, Joana Cardoso, Patrick Franken, Lia Molenaar, Hans Morreau

Am J Pathol· May 2008

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Wnt pathway-related gene expression during malignant progression in ulcerative colitis.
Herman van Dekken, Josiane C Wink, Kees J Vissers, Patrick F Franken, W Ruud Schouten

Acta Histochem· September 2007

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SET-CAN, the product of the t(9;9) in acute undifferentiated leukemia, causes expansion of early hematopoietic progenitors and hyperproliferation of stomach mucosa in transgenic mice.
Ugur Ozbek, Ayten Kandilci, Sjozef van Baal, Jacqueline Bonten, Kelli Boyd, Patrick Franken

Am J Pathol· August 2007

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Genomic analysis of a case of multifocal adenocarcinoma in ulcerative colitis.
Herman van Dekken, Josiane C Wink, Kees J Vissers, Ronald van Marion, Patrick F Franken

Virchows Arch· December 2006

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APC and oncogenic KRAS are synergistic in enhancing Wnt signaling in intestinal tumor formation and progression.
Klaus-Peter Janssen, Paola Alberici, Hafida Fsihi, Claudia Gaspar, Cor Breukel, Patrick Franken

Gastroenterology· October 2006

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