Publications by authors named "Ron Smits"

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Lack of dominant-negative activity for tumor-related ZNRF3 missense mutations at endogenous levels.
Shanshan Li, Jiahui Niu, Ruyi Zhang, Sanne Massaar, Madalena Neves Cabrita, Ron Smits

Oncogene· April 2025

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RNF43 and ZNRF3: Versatile regulators at the membrane and their role in cancer.
Shanshan Li, Jiahui Niu, Ron Smits

Biochim Biophys Acta Rev Cancer· November 2024

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Unraveling the impact of AXIN1 mutations on HCC development: Insights from CRISPR/Cas9 repaired AXIN1-mutant liver cancer cell lines.
Ruyi Zhang, Shanshan Li, Kelly Schippers, Boaz Eimers, Jiahui Niu, Ron Smits

PLoS One· June 2024

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Analysis of Tumor-Associated AXIN1 Missense Mutations Identifies Variants That Activate β-Catenin Signaling.
Ruyi Zhang, Shanshan Li, Kelly Schippers, Yunlong Li, Boaz Eimers, Ron Smits

Cancer Res· May 2024

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Wnt/β-Catenin Signaling Pathway Is Necessary for the Specification but Not the Maintenance of the Mouse Retinal Pigment Epithelium.
Jong-Myeong Kim, Kwang Wook Min, You-Joung Kim, Ron Smits, Konrad Basler

Mol Cells· July 2023

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Issues with RNF43 antibodies to reliably detect intracellular location.
Shanshan Li, Ruyi Zhang, Marla Lavrijsen, Thierry P P van den Bosch, Maikel P Peppelenbosch, Ron Smits

PLoS One· April 2023

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RNF43 mutations predict response to anti-BRAF/EGFR combinatory therapies in BRAF metastatic colorectal cancer.
Elena Elez, Javier Ros, Jose Fernández, Guillermo Villacampa, Ana Belén Moreno-Cárdenas, Ron Smits

Nat Med· October 2022

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Human branching cholangiocyte organoids recapitulate functional bile duct formation.
Floris J M Roos, Gilles S van Tienderen, Haoyu Wu, Ignacio Bordeu, Dina Vinke, Ron Smits

Cell Stem Cell· May 2022

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Cancer-Associated Fibroblasts Provide a Stromal Niche for Liver Cancer Organoids That Confers Trophic Effects and Therapy Resistance.
Jiaye Liu, Pengfei Li, Ling Wang, Meng Li, Zhouhong Ge, Ron Smits

Cell Mol Gastroenterol Hepatol· December 2021

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HOXA13 in etiology and oncogenic potential of Barrett's esophagus.
Vincent T Janmaat, Kateryna Nesteruk, Manon C W Spaander, Auke P Verhaar, Bingting Yu, Ron Smits

Nat Commun· June 2021

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Evaluation of AXIN1 and AXIN2 as targets of tankyrase inhibition in hepatocellular carcinoma cell lines.
Wenhui Wang, Pengyu Liu, Marla Lavrijsen, Shan Li, Ruyi Zhang, Ron Smits

Sci Rep· April 2021

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The biological process of lysine-tRNA charging is therapeutically targetable in liver cancer.
Ruyi Zhang, Lisanne Noordam, Xumin Ou, Buyun Ma, Yunlong Li, Ron Smits

Liver Int· January 2021

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The Functional Landscape of Patient-Derived RNF43 Mutations Predicts Sensitivity to Wnt Inhibition.
Jia Yu, Permeen A Mohamed Yusoff, Daniëlle T J Woutersen, Pamela Goh, Nathan Harmston, Ron Smits

Cancer Res· December 2020

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Differentially Methylated Regions in Desmoid-Type Fibromatosis: A Comparison Between CTNNB1 S45F and T41A Tumors.
Milea J M Timbergen, Ruben Boers, Anne L M Vriends, Joachim Boers, Wilfred F J van IJcken, Ron Smits

Front Oncol· October 2020

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Upregulated β-catenin signaling does not affect survival of pancreatic cancer cells during dual inhibition of GSK3B and HDAC.
Kateryna Nesteruk, Ron Smits, Marco Bruno, Maikel P Peppelenbosch, Gwenny M Fuhler

Pancreatology· April 2020

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Commonly observed RNF43 mutations retain functionality in attenuating Wnt/β-catenin signaling and unlikely confer Wnt-dependency onto colorectal cancers.
Shan Li, Marla Lavrijsen, Aron Bakker, Marcin Magierowski, Katarzyna Magierowska, Ron Smits

Oncogene· April 2020

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Smooth-muscle-derived WNT5A augments allergen-induced airway remodelling and Th2 type inflammation.
Tim Koopmans, Laura Hesse, Martijn C Nawijn, Kuldeep Kumawat, Mark H Menzen, Ron Smits

Sci Rep· April 2020

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LGR5 marks targetable tumor-initiating cells in mouse liver cancer.
Wanlu Cao, Meng Li, Jiaye Liu, Shaoshi Zhang, Lisanne Noordam, Ron Smits

Nat Commun· April 2020

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Oncogenic Mutations in Armadillo Repeats 5 and 6 of β-Catenin Reduce Binding to APC, Increasing Signaling and Transcription of Target Genes.
Pengyu Liu, Binyong Liang, Menggang Liu, Joyce H G Lebbink, Shan Li, Ron Smits

Gastroenterology· March 2020

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HOXA9 mediates and marks premalignant compartment size expansion in colonic adenomas.
Vincent T Janmaat, Hui Liu, Rodrigo A da Silva, Pieter H A Wisse, Manon C W Spaander, Ron Smits

Carcinogenesis· December 2019

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Bacterial biofilms as a potential contributor to mucinous colorectal cancer formation.
Shan Li, Maikel P Peppelenbosch, Ron Smits

Biochim Biophys Acta Rev Cancer· August 2019

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Wnt/β-Catenin Signaling in Liver Cancers.
Wenhui Wang, Ron Smits, Haiping Hao, Chaoyong He

Cancers (Basel)· July 2019

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Activated Signaling Pathways and Targeted Therapies in Desmoid-Type Fibromatosis: A Literature Review.
Milea J M Timbergen, Ron Smits, Dirk J Grünhagen, Cornelis Verhoef, Stefan Sleijfer

Front Oncol· May 2019

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Modeling liver cancer and therapy responsiveness using organoids derived from primary mouse liver tumors.
Wanlu Cao, Jiaye Liu, Ling Wang, Meng Li, Monique M A Verstegen, Ron Smits

Carcinogenesis· March 2019

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Response to: An immunohistochemical approach to detect oncogenic CTNNB1 mutations in primary neoplastic tissues.
Hendrikus J Dubbink, Marla Lavrijsen, Thierry P P van den Bosch, Ron Smits

Lab Invest· March 2019

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