Publications by authors named "Patrick Grohar"

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Molecular Characterization Informs Prognosis in Patients With Localized Ewing Sarcoma: A Report From the Children's Oncology Group.
Riaz Gillani, David S Shulman, Natalie J DelRocco, Kelly Klega, Ruxu Han, Patrick J Grohar

J Clin Oncol· December 2025

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New Approaches to Investigate Novel Agents in Ewing Sarcoma: A Report From the Children's Oncology Group Bone Tumor Committee.
Jessica D Daley, Susan L Whiteway, Christine M Heske, Filemon S Dela Cruz, Sarah B Whittle, Patrick J Grohar

Pediatr Blood Cancer· October 2025

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Advancing preclinical biology for Ewing Sarcoma: an international effort.
Filemon S Dela Cruz, Elizabeth A Stewart, Didier Surdez, Jessica D Daley, Alice Soragni, Patrick J Grohar

Mol Cancer Ther· September 2025

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Advancing Preclinical Biology for Ewing Sarcoma: An International Effort.
Filemon S Dela Cruz, Elizabeth A Stewart, Didier Surdez, Jessica D Daley, Alice Soragni, Patrick J Grohar

Mol Cancer Ther· September 2025

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Comprehensive DSRCT multi-omics analyses unveil CACNA2D2 as a diagnostic hallmark and super-enhancer-driven EWSR1::WT1 signature gene.
Florian Henning Geyer, Alina Ritter, Seneca Kinn-Gurzo, Tobias Faehling, Jing Li, Patrick Joseph Grohar

Cancer Commun (Lond)· June 2025

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Exploiting divergent mechanisms of trabectedin for bone tumors.
Zachary P Tolstyka, Patrick J Grohar

Mol Ther Oncol· June 2025

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Molecular characterization informs prognosis in patients with localized Ewing sarcoma: A report from the Children's Oncology Group.
Riaz Gillani, David S Shulman, Natalie J DelRocco, Kelly Klega, Ruxu Han, Patrick J Grohar

medRxiv· January 2025

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Optimizing Ewing Sarcoma and Osteosarcoma Biopsy Acquisition: A Children's Oncology Group Bone Tumor Committee Consensus Statement.
Matthew S Dietz, Alyaa Al-Ibraheemi, Jessica L Davis, C Matthew Hawkins, Brian T Craig, Patrick J Grohar

J Natl Compr Canc Netw· December 2024

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Cell Context Is the Third Axis of Synergy for the Combination of ATR Inhibition and Cisplatin in Ewing Sarcoma.
Jennifer Jess, Katie M Sorensen, Elissa A Boguslawski, Matthew C Stout, Zachary B Madaj, Patrick J Grohar

Clin Cancer Res· August 2024

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Long-Term Outcomes in Patients With Localized Ewing Sarcoma Treated With Interval-Compressed Chemotherapy on Children's Oncology Group Study AEWS0031.
Thomas Cash, Mark D Krailo, Allen B Buxton, Bruce R Pawel, John H Healey, Patrick J Grohar

J Clin Oncol· October 2023

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Children's Oncology Group's 2023 blueprint for research: Bone tumors.
Damon R Reed, Patrick Grohar, Elyssa Rubin, Odion Binitie, Mark Krailo

Pediatr Blood Cancer· September 2023

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Importance of pharmacologic considerations in the development of targeted anticancer agents for children.
Sridhar M Veluvolu, Patrick J Grohar

Curr Opin Pediatr· February 2023

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An international working group consensus report for the prioritization of molecular biomarkers for Ewing sarcoma.
David S Shulman, Sarah B Whittle, Didier Surdez, Kelly M Bailey, Enrique de Álava, Patrick J Grohar

NPJ Precis Oncol· September 2022

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Ewing sarcoma and related FET family translocation-associated round cell tumors: A century of clinical and scientific progress.
Robert G Maki, Patrick J Grohar, Cristina R Antonescu

Genes Chromosomes Cancer· August 2022

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Lurbinectedin Inhibits the EWS-WT1 Transcription Factor in Desmoplastic Small Round Cell Tumor.
Jenna M Gedminas, Rebecca Kaufman, Elissa A Boguslawski, Amy C Gross, Marie Adams, Patrick J Grohar

Mol Cancer Ther· August 2022

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Oncofusion-driven de novo enhancer assembly promotes malignancy in Ewing sarcoma via aberrant expression of the stereociliary protein LOXHD1.
Qu Deng, Ramakrishnan Natesan, Florencia Cidre-Aranaz, Shehbeel Arif, Ying Liu, Patrick J Grohar

Cell Rep· June 2022

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One oncogene, several vulnerabilities: EWS/FLI targeted therapies for Ewing sarcoma.
Guillermo Flores, Patrick J Grohar

J Bone Oncol· December 2021

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Charting a path for prioritization of novel agents for clinical trials in osteosarcoma: A report from the Children's Oncology Group New Agents for Osteosarcoma Task Force.
Sarah B Whittle, Katharine Offer, Ryan D Roberts, Amy LeBlanc, Cheryl London, Patrick J Grohar

Pediatr Blood Cancer· September 2021

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Mithramycin induces promoter reprogramming and differentiation of rhabdoid tumor.
Maggie H Chasse, Benjamin K Johnson, Elissa A Boguslawski, Katie M Sorensen, Jessica E Rosien, Patrick J Grohar

EMBO Mol Med· February 2021

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Survey of Paediatric Oncologists and Pathologists regarding Their Views and Experiences with Variant Translocations in Ewing and Ewing-Like Sarcoma: A Report of the Children's Oncology Group.
Michael D Kinnaman, Chong Zhu, Daniel A Weiser, Sana Mohiuddin, Pooja Hingorani, Patrick J Grohar

Sarcoma· December 2020

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Emerging novel agents for patients with advanced Ewing sarcoma: a report from the Children's Oncology Group (COG) New Agents for Ewing Sarcoma Task Force.
Kelly Bailey, Carrye Cost, Ian Davis, Julia Glade-Bender, Patrick Grohar

F1000Res· June 2020

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CDK9 Blockade Exploits Context-dependent Transcriptional Changes to Improve Activity and Limit Toxicity of Mithramycin for Ewing Sarcoma.
Guillermo Flores, Joel H Everett, Elissa A Boguslawski, Brandon M Oswald, Zachary B Madaj, Patrick J Grohar

Mol Cancer Ther· May 2020

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Desmoplastic small round cell tumor is dependent on the EWS-WT1 transcription factor.
Jenna M Gedminas, Maggie H Chasse, Mitchell McBrairty, Ian Beddows, Susan M Kitchen-Goosen, Patrick J Grohar

Oncogenesis· April 2020

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Severe Hepatotoxicity of Mithramycin Therapy Caused by Altered Expression of Hepatocellular Bile Transporters.
Tristan M Sissung, Phoebe A Huang, Ralph J Hauke, Edel M McCrea, Cody J Peer, Patrick Grohar

Mol Pharmacol· August 2019

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Trabectedin Inhibits EWS-FLI1 and Evicts SWI/SNF from Chromatin in a Schedule-dependent Manner.
Matt L Harlow, Maggie H Chasse, Elissa A Boguslawski, Katie M Sorensen, Jenna M Gedminas, Patrick J Grohar

Clin Cancer Res· June 2019

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