Publications by authors named "Patrick Gubser"

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Aerobic glycolysis but not GLS1-dependent glutamine metabolism is critical for anti-tumor immunity and response to checkpoint inhibition.
Patrick M Gubser, Sharanya Wijesinghe, Leonie Heyden, Sarah S Gabriel, David P de Souza

Cell Rep· August 2024

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Glutaminase inhibition impairs CD8 T cell activation in STK11-/Lkb1-deficient lung cancer.
Sarah A Best, Patrick M Gubser, Shalini Sethumadhavan, Ariena Kersbergen, Yashira L Negrón Abril

Cell Metab· June 2022

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Transforming growth factor-β-regulated mTOR activity preserves cellular metabolism to maintain long-term T cell responses in chronic infection.
Sarah S Gabriel, Carlson Tsui, David Chisanga, Flora Weber, Manuela Llano-León, Patrick M Gubser

Immunity· August 2021

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Going sugar free: Treg cells avoid glucose to maintain functional fitness.
Patrick M Gubser, Ajithkumar Vasanthakumar

Immunol Cell Biol· July 2021

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Early precursor T cells establish and propagate T cell exhaustion in chronic infection.
Daniel T Utzschneider, Sarah S Gabriel, David Chisanga, Renee Gloury, Patrick M Gubser

Nat Immunol· October 2020

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Methio "mine"! Cancer cells steal methionine and impair CD8 T-cell function.
Patrick M Gubser, Axel Kallies

Immunol Cell Biol· September 2020

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Reference Genes for Expression Studies in Human CD8 Naïve and Effector Memory T Cells under Resting and Activating Conditions.
Marco Geigges, Patrick M Gubser, Gunhild Unterstab, Yannic Lecoultre, Renato Paro

Sci Rep· June 2020

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Tumor-derived TGF-β inhibits mitochondrial respiration to suppress IFN-γ production by human CD4 T cells.
Sarah Dimeloe, Patrick Gubser, Jordan Loeliger, Corina Frick, Leyla Develioglu

Sci Signal· September 2019

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Early effector maturation of naïve human CD8 T cells requires mitochondrial biogenesis.
Marco Fischer, Glenn R Bantug, Sarah Dimeloe, Patrick M Gubser, Anne-Valérie Burgener

Eur J Immunol· October 2018

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Mitochondria-Endoplasmic Reticulum Contact Sites Function as Immunometabolic Hubs that Orchestrate the Rapid Recall Response of Memory CD8 T Cells.
Glenn R Bantug, Marco Fischer, Jasmin Grählert, Maria L Balmer, Gunhild Unterstab, Patrick M Gubser

Immunity· March 2018

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Human regulatory T cells lack the cyclophosphamide-extruding transporter ABCB1 and are more susceptible to cyclophosphamide-induced apoptosis.
Sarah Dimeloe, Corina Frick, Marco Fischer, Patrick M Gubser, Leyla Razik

Eur J Immunol· December 2014

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Rapid effector function of memory CD8+ T cells requires an immediate-early glycolytic switch.
Patrick M Gubser, Glenn R Bantug, Leyla Razik, Marco Fischer, Sarah Dimeloe

Nat Immunol· October 2013

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Epstein-Barr virus negativity among individuals older than 60 years is associated with HLA-C and HLA-Bw4 variants and tonsillectomy.
Bojana Durovic, Olivier Gasser, Patrick Gubser, Jörg Sigle, Hans H Hirsch

J Virol· June 2013

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Homing frequency of human T cells inferred from peripheral blood depletion kinetics after sphingosine-1-phosphate receptor blockade.
Matthias Mehling, Volker Brinkmann, Anne-Valerie Burgener, Patrick Gubser, Andrew D Luster

J Allergy Clin Immunol· May 2013

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A high-mobility, low-cost phenotype defines human effector-memory CD8+ T cells.
Gabriela Zenhaeusern, Patrick Gubser, Petra Eisele, Olivier Gasser, Andrea Steinhuber

Blood· January 2009

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