Publications by authors named "Patrick Haslett"

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Evaluation of RNAi therapeutics VIR-2218 and ALN-HBV for chronic hepatitis B: Results from randomized clinical trials.
Ed Gane, Young-Suk Lim, Jae B Kim, Vasant Jadhav, Ling Shen, Patrick Haslett

J Hepatol· October 2023

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From bench to bedside: Improving the clinical safety of GalNAc-siRNA conjugates using seed-pairing destabilization.
Mark K Schlegel, Maja M Janas, Yongfeng Jiang, Joseph D Barry, Wendell Davis, Patrick Haslett

Nucleic Acids Res· July 2022

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Phase 1/2 Study of Lumasiran for Treatment of Primary Hyperoxaluria Type 1: A Placebo-Controlled Randomized Clinical Trial.
Yaacov Frishberg, Georges Deschênes, Jaap W Groothoff, Sally-Anne Hulton, Daniella Magen, Patrick Haslett

Clin J Am Soc Nephrol· July 2021

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GWAS of serum ALT and AST reveals an association of SLC30A10 Thr95Ile with hypermanganesemia symptoms.
Lucas D Ward, Ho-Chou Tu, Chelsea B Quenneville, Shira Tsour, Alexander O Flynn-Carroll, Patrick A J Haslett

Nat Commun· July 2021

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RNA Interference Targeting Liver Angiopoietin-Like Protein 3 Protects from Nephrotic Syndrome in a Rat Model Via Amelioration of Pathologic Hypertriglyceridemia.
Yitong Zhao, Masaki Goto, Nosratola D Vaziri, Mahyar Khazaeli, Han Liu, Patrick A Haslett

J Pharmacol Exp Ther· March 2021

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Activation of Protein Kinase A (PKA) signaling mitigates congenital hyperinsulinism associated hypoglycemia in the Sur1-/- mouse model.
Mangala M Soundarapandian, Christine A Juliana, Jinghua Chai, Patrick A Haslett, Kevin Fitzgerald

PLoS One· September 2020

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Increased Plasma Levels of the TH2 chemokine CCL18 associated with low CD4+ T cell counts in HIV-1-infected Patients with a Suppressed Viral Load.
Prashant Malhotra, Patrick Haslett, Barbara Sherry, David H Shepp, Paul Barber

Sci Rep· April 2019

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Improving Drug Discovery by Nucleic Acid Delivery in Engineered Human Microlivers.
Liliana Mancio-Silva, Heather E Fleming, Alex B Miller, Stuart Milstein, Abigail Liebow, Patrick Haslett

Cell Metab· March 2019

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Observational Prospective Natural History of Patients with Sanfilippo Syndrome Type B.
Chester B Whitley, Maureen Cleary, Karl Eugen Mengel, Paul Harmatz, Elsa Shapiro, Patrick Haslett

J Pediatr· June 2018

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An Investigational RNAi Therapeutic Targeting Glycolate Oxidase Reduces Oxalate Production in Models of Primary Hyperoxaluria.
Abigail Liebow, Xingsheng Li, Timothy Racie, Julia Hettinger, Brian R Bettencourt, Patrick Haslett

J Am Soc Nephrol· February 2017

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A phase 1/2 study of intrathecal heparan-N-sulfatase in patients with mucopolysaccharidosis IIIA.
Simon A Jones, Catherine Breen, Fiona Heap, Stewart Rust, Jessica de Ruijter, Patrick A J Haslett

Mol Genet Metab· July 2016

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A Prospective Natural History Study of Mucopolysaccharidosis Type IIIA.
Elsa G Shapiro, Igor Nestrasil, Kathleen A Delaney, Kyle Rudser, Victor Kovac, Patrick Haslett

J Pediatr· March 2016

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A novel LC-MS/MS assay for heparan sulfate screening in the cerebrospinal fluid of mucopolysaccharidosis IIIA patients.
Hicham Naimy, Kendall D Powell, John R Moriarity, Jiang Wu, Thomas G McCauley, Patrick Aj Haslett

Bioanalysis· February 2016

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Quantifying behaviors of children with Sanfilippo syndrome: the Sanfilippo Behavior Rating Scale.
Elsa G Shapiro, Igor Nestrasil, Alia Ahmed, Andrew Wey, Kyle R Rudser, Patrick A J Haslett

Mol Genet Metab· April 2015

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Methods of neurodevelopmental assessment in children with neurodegenerative disease: Sanfilippo syndrome.
Kathleen A Delaney, Kyle R Rudser, Brianna D Yund, Chester B Whitley, Patrick A J Haslett

JIMD Rep· July 2014

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IL-17A is essential for cell activation and inflammatory gene circuits in subjects with psoriasis.
James G Krueger, Scott Fretzin, Mayte Suárez-Fariñas, Patrick A Haslett, Krista M Phipps

J Allergy Clin Immunol· July 2012

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Lower numbers of natural killer T cells in HIV-1 and Mycobacterium leprae co-infected patients.
Karina I Carvalho, Fernanda R Bruno, Jennifer E Snyder-Cappione, Solange M Maeda, Jane Tomimori, Patrick A Haslett

Immunology· May 2012

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Lessons of leprosy: the emergence of TH17 cytokines during type II reactions (ENL) is teaching us about T-cell plasticity.
Frank Martiniuk, Jerome Giovinazzo, Ainah U Tan, Rozana Shahidullah, Patrick Haslett

J Drugs Dermatol· May 2012

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A potential role for complement in immune evasion by Mycobacterium leprae.
Donato Callegaro-Filho, Niraj Shrestha, Anne E Burdick, Patrick A J Haslett

J Drugs Dermatol· November 2010

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Immune cellular parameters of leprosy and human immunodeficiency virus-1 co-infected subjects.
Karina I Carvalho, Solange Maeda, Luciana Marti, Jane Yamashita, Patrick A J Haslett

Immunology· June 2008

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Impaired CCR7 expression on plasmacytoid dendritic cells of HIV-infected children and adolescents with immunologic and virologic failure.
Seema Desai, Aida Chaparro, Huanliang Liu, Patrick Haslett, Kristopher Arheart

J Acquir Immune Defic Syndr· August 2007

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Selective defect in plasmacyoid dendritic cell function in a patient with AIDS-associated atypical genital herpes simplex vegetans treated with imiquimod.
Lillian Abbo, Vladimir Vincek, Gordon Dickinson, Niraj Shrestha, Susanne Doblecki, Patrick A J Haslett

Clin Infect Dis· February 2007

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A whole blood assay to assess peripheral blood dendritic cell function in response to Toll-like receptor stimulation.
James A Ida, Niraj Shrestha, Seema Desai, Savita Pahwa, Willem A Hanekom, Patrick A J Haslett

J Immunol Methods· March 2006

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Effective treatment of erythema nodosum leprosum with thalidomide is associated with immune stimulation.
Patrick A J Haslett, Paul Roche, C Ruth Butlin, Murdo Macdonald, Niraj Shrestha

J Infect Dis· December 2005

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Regulation of acquired immunity by gamma delta T-cell/dendritic-cell interactions.
Niraj Shrestha, James A Ida, A Steven Lubinski, Maria Pallin, Gilla Kaplan, Patrick A J Haslett

Ann N Y Acad Sci· December 2005

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