Publications by authors named "Patrick Holt"

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Immune impacts of infant whole-cell and acellular pertussis vaccination on co-administered vaccines.
Gladymar Pérez Chacón, Sonia McAlister, James Totterdell, Marie J Estcourt, Julie A Marsh, Patrick G Holt

J Infect· July 2025

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Atopy-related immune profiles are subject to genetic influence as evaluated using school-aged twin pairs.
Jonatan Leffler, James F Read, Danny Mok, Michael Serralha, Anthony Bosco, Patrick G Holt

Sci Adv· July 2025

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Mapping Lung Hematopoietic Progenitors: Developmental Kinetics and Response to Influenza A Infection.
Kyle T Mincham, Jean-Francois Lauzon-Joset, James F Read, Patrick G Holt, Philip A Stumbles

Am J Respir Cell Mol Biol· August 2024

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Immunogenicity, reactogenicity, and IgE-mediated immune responses of a mixed whole-cell and acellular pertussis vaccine schedule in Australian infants: A randomised, double-blind, noninferiority trial.
Gladymar Pérez Chacón, Marie J Estcourt, James Totterdell, Julie A Marsh, Kirsten P Perrett, Patrick G Holt

PLoS Med· June 2024

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Impaired interferon response in plasmacytoid dendritic cells from children with persistent wheeze.
Isabelle Coenen, Emma de Jong, Anya C Jones, Siew-Kim Khoo, Shihui Foo, Patrick G Holt

J Allergy Clin Immunol· April 2024

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Single cell transcriptomics reveals cell type specific features of developmentally regulated responses to lipopolysaccharide between birth and 5 years.
James F Read, Michael Serralha, Jesse D Armitage, Muhammad Munir Iqbal, Mark N Cruickshank, Patrick G Holt

Front Immunol· November 2023

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European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation.
Ashley Budu-Aggrey, Anna Kilanowski, Maria K Sobczyk, , Suyash S Shringarpure, Patrick G Holt

Nat Commun· October 2023

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Rhinoviruses A and C elicit long-lasting antibody responses with limited cross-neutralization.
Yury A Bochkov, Mark Devries, Kaitlin Tetreault, Ronald Gangnon, Sujin Lee, Patrick Holt

J Med Virol· August 2023

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LPS binding protein and activation signatures are upregulated during asthma exacerbations in children.
Anya C Jones, Jonatan Leffler, Ingrid A Laing, Joelene Bizzintino, Siew-Kim Khoo, Patrick G Holt

Respir Res· July 2023

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Maternal diet modulates the infant microbiome and intestinal Flt3L necessary for dendritic cell development and immunity to respiratory infection.
Md Al Amin Sikder, Ridwan B Rashid, Tufael Ahmed, Ismail Sebina, Daniel R Howard, Patrick G Holt

Immunity· May 2023

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Asthma and allergies in a cohort of adolescents conceived with ART.
Laura A Wijs, Dorota A Doherty, Jeffrey A Keelan, Blagica Penova-Veselinovic, Peter Burton, Patrick G Holt

Reprod Biomed Online· December 2022

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Remission of peanut allergy is associated with rewiring of allergen-driven T helper 2-related gene networks.
Sarah E Ashley, Anya C Jones, Denise Anderson, Patrick G Holt, Anthony Bosco

Allergy· October 2022

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Lipopolysaccharide-induced interferon response networks at birth are predictive of severe viral lower respiratory infections in the first year of life.
James F Read, Michael Serralha, Danny Mok, Barbara J Holt, Mark Cruickshank, Patrick G Holt

Front Immunol· August 2022

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Protection against severe infant lower respiratory tract infections by immune training: Mechanistic studies.
Niamh M Troy, Deborah Strickland, Michael Serralha, Emma de Jong, Anya C Jones, Barbara J Holt, Patrick G Holt

J Allergy Clin Immunol· July 2022

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IRF7-Associated Immunophenotypes Have Dichotomous Responses to Virus/Allergen Coexposure and OM-85-Induced Reprogramming.
Emma de Jong, Jean-Francois Lauzon-Joset, Jonatan Leffler, Michael Serralha, Alexander N Larcombe, Patrick G Holt

Front Immunol· December 2021

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Cord-blood respiratory syncytial virus antibodies and respiratory health in first 5 years of life.
Mari D Takashima, Keith Grimwood, Peter D Sly, Stephen B Lambert, Keith J Chappell, Barbara Holt, Patrick Holt

Pediatr Pulmonol· December 2021

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Rare variant analysis in eczema identifies exonic variants in DUSP1, NOTCH4 and SLC9A4.
Sarah Grosche, Ingo Marenholz, Jorge Esparza-Gordillo, Aleix Arnau-Soler, Erola Pairo-Castineira, Patrick G Holt

Nat Commun· November 2021

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Time spent outdoors through childhood and adolescence - assessed by 25-hydroxyvitamin D concentration - and risk of myopia at 20 years.
Gareth Lingham, David A Mackey, Kun Zhu, Robyn M Lucas, Lucinda J Black, Patrick Holt

Acta Ophthalmol· September 2021

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Whole-cell pertussis vaccine in early infancy for the prevention of allergy in children.
Gladymar Perez Chacon, Jessica Ramsay, Christopher G Brennan-Jones, Marie J Estcourt, Peter Richmond, Patrick Holt

Cochrane Database Syst Rev· September 2021

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Innate Immune Training for Prevention of Recurrent Wheeze in Early Childhood.
Patrick Holt, Deborah Strickland

Am J Respir Crit Care Med· August 2021

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Protection against neonatal respiratory viral infection via maternal treatment during pregnancy with the benign immune training agent OM-85.
Jean-Francois Lauzon-Joset, Kyle T Mincham, Naomi M Scott, Yasmine Khandan, Philip A Stumbles, Patrick G Holt

Clin Transl Immunology· July 2021

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Transplacental Innate Immune Training via Maternal Microbial Exposure: Role of XBP1-ERN1 Axis in Dendritic Cell Precursor Programming.
Kyle T Mincham, Anya C Jones, Marie Bodinier, Naomi M Scott, Jean-Francois Lauzon-Joset, Patrick G Holt

Front Immunol· June 2021

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Enhanced Neutralizing Antibody Responses to Rhinovirus C and Age-Dependent Patterns of Infection.
Timothy Choi, Mark Devries, Leonard B Bacharier, William Busse, Carlos A Camargo, Patrick Holt

Am J Respir Crit Care Med· April 2021

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The intersect of genetics, environment, and microbiota in asthma-perspectives and challenges.
Howard H F Tang, Shu Mei Teo, Peter D Sly, Patrick G Holt, Michael Inouye

J Allergy Clin Immunol· March 2021

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OPTIMUM study protocol: an adaptive randomised controlled trial of a mixed whole-cell/acellular pertussis vaccine schedule.
Gladymar Perez Chacon, Marie J Estcourt, James Totterdell, Dianne E Campbell, Kirsten P Perrett, Patrick G Holt

BMJ Open· December 2020

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