Publications by authors named "Patrick Mayes"

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Discovery of Fluoroalkenes as Dual Inhibitors of Diacylglycerol Kinases Alpha and Zeta (DGKα/ζ).
Ming Xiang, Shicheng Shi, Shaoqun Qian, Chengtsung Lai, Kelly Federowicz, Patrick Mayes

J Med Chem· October 2025

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Selective targeting of mutated calreticulin by the monoclonal antibody INCA033989 inhibits oncogenic function of MPN.
Edimara S Reis, Rebecca Buonpane, Hamza Celik, Caroline Marty, Angela Lei, Patrick A Mayes

Blood· November 2024

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Correction: Identification of TRAIL-inducing compounds highlights small molecule ONC201/TIC10 as a unique anti-cancer agent that activates the TRAIL pathway.
Joshua E Allen, Gabriel Krigsfeld, Luv Patel, Patrick A Mayes, David T Dicker

Mol Cancer· October 2024

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Activating Inducible T-cell Costimulator Yields Antitumor Activity Alone and in Combination with Anti-PD-1 Checkpoint Blockade.
Sapna Yadavilli, Jeremy D Waight, Sara Brett, Meixia Bi, Tianqian Zhang, Patrick A Mayes

Cancer Res Commun· August 2023

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Belantamab Mafodotin (GSK2857916) Drives Immunogenic Cell Death and Immune-mediated Antitumor Responses .
Rocio Montes de Oca, Alireza S Alavi, Nick Vitali, Sabyasachi Bhattacharya, Christina Blackwell, Patrick Mayes

Mol Cancer Ther· October 2021

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A human CD137×PD-L1 bispecific antibody promotes anti-tumor immunity via context-dependent T cell costimulation and checkpoint blockade.
Cecile Geuijen, Paul Tacken, Liang-Chuan Wang, Rinse Klooster, Pieter Fokko van Loo, Patrick A Mayes

Nat Commun· July 2021

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CXCR5 and ICOS expression identifies a CD8 T-cell subset with T features in Hodgkin lymphomas.
Kieu-Suong Le, Patricia Amé-Thomas, Karin Tarte, Françoise Gondois-Rey, Samuel Granjeaud, Patrick A Mayes

Blood Adv· August 2018

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The promise and challenges of immune agonist antibody development in cancer.
Patrick A Mayes, Kenneth W Hance, Axel Hoos

Nat Rev Drug Discov· July 2018

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Evaluation of B cell maturation antigen as a target for antibody drug conjugate mediated cytotoxicity in multiple myeloma.
Lydia Lee, Danton Bounds, Jennifer Paterson, Gaelle Herledan, Katherine Sully, Patrick A Mayes

Br J Haematol· September 2016

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Identification of TRAIL-inducing compounds highlights small molecule ONC201/TIC10 as a unique anti-cancer agent that activates the TRAIL pathway.
Joshua E Allen, Gabriel Krigsfeld, Luv Patel, Patrick A Mayes, David T Dicker

Mol Cancer· May 2015

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The BRAF and MEK Inhibitors Dabrafenib and Trametinib: Effects on Immune Function and in Combination with Immunomodulatory Antibodies Targeting PD-1, PD-L1, and CTLA-4.
Li Liu, Patrick A Mayes, Stephen Eastman, Hong Shi, Sapna Yadavilli

Clin Cancer Res· April 2015

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Novel anti-B-cell maturation antigen antibody-drug conjugate (GSK2857916) selectively induces killing of multiple myeloma.
Yu-Tzu Tai, Patrick A Mayes, Chirag Acharya, Mike Y Zhong, Michele Cea

Blood· May 2014

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Mitogen-activated protein kinase (MEK/ERK) inhibition sensitizes cancer cells to centromere-associated protein E inhibition.
Patrick A Mayes, Yan Y Degenhardt, Andrew Wood, Yana Toporovskya, Sharon J Diskin

Int J Cancer· February 2013

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Dual inactivation of Akt and ERK by TIC10 signals Foxo3a nuclear translocation, TRAIL gene induction, and potent antitumor effects.
Joshua E Allen, Gabriel Krigsfeld, Patrick A Mayes, Luv Patel, David T Dicker

Sci Transl Med· February 2013

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ATF4 regulates MYC-mediated neuroblastoma cell death upon glutamine deprivation.
Guoliang Qing, Bo Li, Annette Vu, Nicolas Skuli, Zandra E Walton, Patrick A Mayes

Cancer Cell· November 2012

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Overcoming hypoxia-induced apoptotic resistance through combinatorial inhibition of GSK-3β and CDK1.
Patrick A Mayes, Nathan G Dolloff, Colin J Daniel, J Judy Liu, Lori S Hart

Cancer Res· August 2011

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FLT-PET may not be a reliable indicator of therapeutic response in p53-null malignancy.
Sharyn I Katz, Lanlan Zhou, Thomas A Ferrara, Wenge Wang, Patrick A Mayes

Int J Oncol· July 2011

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Off-target lapatinib activity sensitizes colon cancer cells through TRAIL death receptor up-regulation.
Nathan G Dolloff, Patrick A Mayes, Lori S Hart, David T Dicker, Robin Humphreys

Sci Transl Med· June 2011

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RNAi screen of the protein kinome identifies checkpoint kinase 1 (CHK1) as a therapeutic target in neuroblastoma.
Kristina A Cole, Jonathan Huggins, Michael Laquaglia, Chase E Hulderman, Mike R Russell, Patrick A Mayes

Proc Natl Acad Sci U S A· February 2011

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Integrative genomics identifies LMO1 as a neuroblastoma oncogene.
Kai Wang, Sharon J Diskin, Haitao Zhang, Edward F Attiyeh, Cynthia Winter, Patrick A Mayes

Nature· January 2011

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Combinatorial regulation of neuroblastoma tumor progression by N-Myc and hypoxia inducible factor HIF-1alpha.
Guoliang Qing, Nicolas Skuli, Patrick A Mayes, Bruce Pawel, Daniel Martinez

Cancer Res· December 2010

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Serial transcriptome analysis and cross-species integration identifies centromere-associated protein E as a novel neuroblastoma target.
Naomi J Balamuth, Andrew Wood, Qun Wang, Jayanti Jagannathan, Patrick Mayes

Cancer Res· April 2010

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TNFSF10 (TRAIL), a p53 target gene that mediates p53-dependent cell death.
Kageaki Kuribayashi, Gabriel Krigsfeld, Wenge Wang, Jing Xu, Patrick A Mayes

Cancer Biol Ther· December 2008

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Noninvasive vascular imaging in fluorescent tumors using multispectral unmixing.
Patrick Mayes, David Dicker, Yingqiu Liu, Wafik El-Deiry

Biotechniques· October 2008

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The complementary roles of the extrinsic and intrinsic apoptotic pathways in promoting the death of cancer cells.
Patrick A Mayes, Wafik S El-Deiry

Cancer J· December 2006

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