Publications by authors named "Robin Humphreys"

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Quality improvement initiative to improve inpatient outcomes for Neonatal Abstinence Syndrome.
Elisha M Wachman, Matthew Grossman, Davida M Schiff, Barbara L Philipp, Susan Minear, Robin Humphreys

J Perinatol· August 2018

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Revision of Breastfeeding Guidelines in the Setting of Maternal Opioid Use Disorder: One Institution's Experience.
Elisha M Wachman, Kelley Saia, Robin Humphreys, Susan Minear, Ginny Combs

J Hum Lact· May 2016

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Induction of potent NK cell-dependent anti-myeloma cytotoxic T cells in response to combined mapatumumab and bortezomib.
Paul J Neeson, Andy K Hsu, Yin R Chen, Heloise M Halse, Joanna Loh, Robin Humphreys

Oncoimmunology· September 2015

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Sorafenib sensitizes solid tumors to Apo2L/TRAIL and Apo2L/TRAIL receptor agonist antibodies by the Jak2-Stat3-Mcl1 axis.
Junaid Abdulghani, Joshua E Allen, David T Dicker, Yingqiu Yvette Liu, David Goldenberg, Robin Humphreys

PLoS One· July 2014

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Phase II trial of mapatumumab, a fully human agonist monoclonal antibody to tumor necrosis factor-related apoptosis-inducing ligand receptor 1 (TRAIL-R1), in combination with paclitaxel and carboplatin in patients with advanced non-small-cell lung cancer.
Joachim von Pawel, Jimmie H Harvey, David R Spigel, Mircea Dediu, Martin Reck, Robin C Humphreys

Clin Lung Cancer· May 2014

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Fusion toxin BLyS-gelonin inhibits growth of malignant human B cell lines in vitro and in vivo.
Troy A Luster, Ipsita Mukherjee, Jeffrey A Carrell, Yun Hee Cho, Jeffrey Gill, Robin Humphreys

PLoS One· May 2013

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RIP1 protein-dependent assembly of a cytosolic cell death complex is required for inhibitor of apoptosis (IAP) inhibitor-mediated sensitization to lexatumumab-induced apoptosis.
Farhan Basit, Robin Humphreys, Simone Fulda

J Biol Chem· November 2012

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Mitomycin C potentiates TRAIL-induced apoptosis through p53-independent upregulation of death receptors: evidence for the role of c-Jun N-terminal kinase activation.
Hairong Cheng, Bo Hong, Lanlan Zhou, Joshua E Allen, Guihua Tai, Robin Humphreys

Cell Cycle· September 2012

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Pediatric neurosurgery at the Hospital for Sick Children, The University of Toronto.
James T Rutka, James Drake, Peter Dirks, Abhaya Kulkarni, Michael Taylor, Robin P Humphreys

Childs Nerv Syst· August 2012

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Spectral imaging-based methods for quantifying autophagy and apoptosis.
Nathan G Dolloff, Xiahong Ma, David T Dicker, Robin C Humphreys, Lin Z Li

Cancer Biol Ther· August 2011

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Prediction of proapoptotic anticancer therapeutic response in vivo based on cell death visualization and TRAIL death ligand-receptor interaction.
LanLan Zhou, Wenge Wang, David T Dicker, Robin C Humphreys, Wafik S El-Deiry

Cancer Biol Ther· August 2011

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Off-target lapatinib activity sensitizes colon cancer cells through TRAIL death receptor up-regulation.
Nathan G Dolloff, Patrick A Mayes, Lori S Hart, David T Dicker, Robin Humphreys

Sci Transl Med· June 2011

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TRAIL-induced apoptosis is preferentially mediated via TRAIL receptor 1 in pancreatic carcinoma cells and profoundly enhanced by XIAP inhibitors.
Dominic Stadel, Andrea Mohr, Caroline Ref, Marion MacFarlane, Shaoxia Zhou, Robin Humphreys

Clin Cancer Res· December 2010

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Human monomeric antibody fragments to TRAIL-R1 and TRAIL-R2 that display potent in vitro agonism.
Claire L Dobson, Sarah Main, Philip Newton, Matthieu Chodorge, Karen Cadwallader, Robin Humphreys

MAbs· June 2010

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Tumor Necrosis Factor-related apoptosis-inducing ligand (TRAIL) Receptor-1 and Receptor-2 agonists for cancer therapy.
Norma Lynn Fox, Robin Humphreys, Troy A Luster, Jerry Klein, Gilles Gallant

Expert Opin Biol Ther· January 2010

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Efficacy of triple therapies including ionising radiation, agonistic TRAIL antibodies and cisplatin.
Maximilian Niyazi, Patrizia Marini, Peter T Daniel, Robin Humphreys, Verena Jendrossek

Oncol Rep· June 2009

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A double hit to kill tumor and endothelial cells by TRAIL and antiangiogenic 3TSR.
Bin Ren, Keli Song, Sareh Parangi, Taiguang Jin, Min Ye, Robin Humphreys

Cancer Res· May 2009

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Mapatumumab and lexatumumab induce apoptosis in TRAIL-R1 and TRAIL-R2 antibody-resistant NSCLC cell lines when treated in combination with bortezomib.
Troy A Luster, Jeffrey A Carrell, Kathy McCormick, David Sun, Robin Humphreys

Mol Cancer Ther· February 2009

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Efficacy of a triple treatment with irradiation, agonistic TRAIL receptor antibodies and EGFR blockade.
Maximilian Niyazi, Patrizia Marini, Peter T Daniel, Robin Humphreys, Verena Jendrossek

Strahlenther Onkol· January 2009

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Trail receptors: targets for cancer therapy.
Robin C Humphreys, Wendy Halpern

Adv Exp Med Biol· May 2008

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Distribution of industry-sponsored diaper bags from maternity facilities in Massachusetts.
Barbara L Philipp, Deborah A Frank, Robin J Humphreys, Sheina Jean-Marie

Breastfeed Med· December 2007

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Tumor-derived mutations in the TRAIL receptor DR5 inhibit TRAIL signaling through the DR4 receptor by competing for ligand binding.
Lianghua Bin, Jacqueline Thorburn, Lance R Thomas, Peter E Clark, Robin Humphreys

J Biol Chem· September 2007

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The history of neurosurgery at the Hospital for Sick Children in Toronto.
Andrew Jea, Merdas Al-Otibi, James T Rutka, James M Drake, Peter B Dirks, Robin P Humphreys

Neurosurgery· September 2007

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Histone deacetylase inhibitors enhance lexatumumab-induced apoptosis via a p21Cip1-dependent decrease in survivin levels.
Steffan T Nawrocki, Jennifer S Carew, Leslie Douglas, John L Cleveland, Robin Humphreys

Cancer Res· July 2007

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A small molecule Smac mimic potentiates TRAIL-mediated cell death of ovarian cancer cells.
Eleonora Petrucci, Luca Pasquini, Alessia Petronelli, Ernestina Saulle, Gualtiero Mariani, Robin Humphreys

Gynecol Oncol· May 2007

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