Publications by authors named "Patrick Ryan Potts"

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A cancer-specific antigen drives histone acetylation by stabilizing the acetyltransferases.
Xuekun Fu, Xu Yang, Jie Huang, Yuhong Huang, Patrick Ryan Potts

Cell Rep· October 2025

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Load and lock: An emerging class of therapeutics that influence macromolecular dissociation.
Raymond J Deshaies, Patrick Ryan Potts

Science· August 2025

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Sticky business: Rationalizing CRBN's zinc-finger targeting by molecular glues.
Jonathan W Bushman, Patrick Ryan Potts

Mol Cell· August 2025

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LYMTACs:chimeric small molecules repurpose lysosomal membrane proteins for target protein relocalization and degradation.
Dhanusha A Nalawansha, Georgios Mazis, Gitte Husemoen, Kate S Ashton, Weixian Deng, Patrick Ryan Potts

Nat Commun· August 2025

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Melanoma antigens in pediatric medulloblastoma contribute to tumor heterogeneity and species-specificity of group 3 tumors.
Rebecca R J Collins, Rebecca R Florke Gee, Sima Tozandehjani, Tara Bayat, Maria Camila Hoyos Sanchez, Patrick Ryan Potts

Acta Neuropathol Commun· July 2025

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Covalent Destabilizing Degrader of AR and AR-V7 in Androgen-Independent Prostate Cancer Cells.
Charlotte M Zammit, Cory M Nadel, Ying Lin, Sajjan Koirala, Elnaz Ahani, Patrick Ryan Potts

J Am Chem Soc· June 2025

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Molecular glue unexpectedly mimics the effect of cancer mutations.
Jonathan W Bushman, Patrick Ryan Potts

Nature· March 2025

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VIPER-TACs leverage viral E3 ligases for disease-specific targeted protein degradation.
Kyle Mangano, Robert G Guenette, Spencer Hill, Shiqian Li, Jeffrey J Liu, Patrick Ryan Potts

Cell Chem Biol· March 2025

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Covalent Destabilizing Degrader of AR and AR-V7 in Androgen-Independent Prostate Cancer Cells.
Charlotte M Zammit, Cory M Nadel, Ying Lin, Sajjan Koirala, Patrick Ryan Potts

bioRxiv· February 2025

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Feel the breeze: Opening the therapeutic window with RIPTACs and induced proximity.
Kyle Mangano, Patrick Ryan Potts

Cell Chem Biol· August 2024

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RNATACs: Multispecific small molecules targeting RNA by induced proximity.
Yan Song, Jia Cui, Jiaqiang Zhu, Boseon Kim, Mei-Ling Kuo, Patrick Ryan Potts

Cell Chem Biol· June 2024

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Melanoma antigens in pediatric medulloblastoma contribute to tumor heterogeneity and species-specificity of group 3 tumors.
Rebecca R J Collins, Rebecca R Florke Gee, Maria Camila Hoyos Sanchez, Sima Tozandehjani, Tara Bayat, Patrick Ryan Potts

bioRxiv· May 2024

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TAC-tics for Leveraging Proximity Biology in Drug Discovery.
Dhanusha A Nalawansha, Kyle Mangano, Willem den Besten, Patrick Ryan Potts

Chembiochem· February 2024

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Protein-protein interfaces in molecular glue-induced ternary complexes: classification, characterization, and prediction.
Huan Rui, Kate S Ashton, Jaeki Min, Connie Wang, Patrick Ryan Potts

RSC Chem Biol· March 2023

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High throughput E3 ligase degron binding assays for novel PROTAC ligand discovery.
Robert G Guenette, Patrick Ryan Potts

Methods Enzymol· February 2023

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Target and tissue selectivity of PROTAC degraders.
Robert G Guenette, Seung Wook Yang, Jaeki Min, Baikang Pei, Patrick Ryan Potts

Chem Soc Rev· July 2022

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Phenyl-Glutarimides: Alternative Cereblon Binders for the Design of PROTACs.
Jaeki Min, Anand Mayasundari, Fatemeh Keramatnia, Barbara Jonchere, Seung Wook Yang, Patrick Ryan Potts

Angew Chem Int Ed Engl· December 2021

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Protocol for the determination of intracellular phase separation thresholds.
Anna K Lee, Patrick Ryan Potts

STAR Protoc· March 2021

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Emerging roles of the MAGE protein family in stress response pathways.
Rebecca R Florke Gee, Helen Chen, Anna K Lee, Christina A Daly, Benjamin A Wilander, Patrick Ryan Potts

J Biol Chem· November 2020

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Structural basis for substrate recognition and chemical inhibition of oncogenic MAGE ubiquitin ligases.
Seung Wook Yang, Xin Huang, Wenwei Lin, Jaeki Min, Darcie J Miller, Patrick Ryan Potts

Nat Commun· October 2020

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CSAG2 is a cancer-specific activator of SIRT1.
Xu Yang, Patrick Ryan Potts

EMBO Rep· September 2020

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Loss of MAGEL2 in Prader-Willi syndrome leads to decreased secretory granule and neuropeptide production.
Helen Chen, A Kaitlyn Victor, Jonathon Klein, Klementina Fon Tacer, Derek Jc Tai, Patrick Ryan Potts

JCI Insight· September 2020

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Translational Repression of G3BP in Cancer and Germ Cells Suppresses Stress Granules and Enhances Stress Tolerance.
Anna K Lee, Jonathon Klein, Klementina Fon Tacer, Tessa Lord, Melissa J Oatley, Patrick Ryan Potts

Mol Cell· August 2020

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Tissue-Specific Regulation of the Wnt/β-Catenin Pathway by PAGE4 Inhibition of Tankyrase.
Sajjan Koirala, Jonathon Klein, Yumei Zheng, Nicole O Glenn, Travis Eisemann, Patrick Ryan Potts

Cell Rep· July 2020

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A Cancer-Specific Ubiquitin Ligase Drives mRNA Alternative Polyadenylation by Ubiquitinating the mRNA 3' End Processing Complex.
Seung Wook Yang, Lei Li, Jon P Connelly, Shaina N Porter, Kiran Kodali, Patrick Ryan Potts

Mol Cell· March 2020

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