Publications by authors named "Xuekun Fu"

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snoRNA promotes rheumatoid arthritis by epigenetic regulation of ESM1 in fibroblast-like synoviocytes in mice.
Jie Huang, Xuekun Fu, Runrun Zhang, Zhuqian Wang, Fang Qiu

Sci Transl Med· November 2025

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A cancer-specific antigen drives histone acetylation by stabilizing the acetyltransferases.
Xuekun Fu, Xu Yang, Jie Huang, Yuhong Huang, Patrick Ryan Potts

Cell Rep· October 2025

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Development of Injectable Aldehyde Hyaluronic Acid Hydrogels Loaded with CRISPRa Reprogrammed Elite Macrophages for the Treatment of Osteoarthritis.
Xuekun Fu, Chuanxin Zhong, Wentao Liu, Fuzeng Ren, Chao Liang

ACS Appl Mater Interfaces· June 2025

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Generation of cytotoxic aptamers specifically targeting fibroblast-like synoviocytes by CSCT-SELEX for treatment of rheumatoid arthritis.
Fang Qiu, Duoli Xie, Hongzhen Chen, Zhuqian Wang, Jie Huang, Xuekun Fu

Ann Rheum Dis· May 2025

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Correction to "Discovery of a Natural Ent-Kaurene Diterpenoid Oridonin as an E3 Ligase Recruiter for PROTACs".
Jie Huang, Xuekun Fu, Fang Qiu, Zhijian Liang, Chunhao Cao

J Am Chem Soc· April 2025

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Discovery of a Natural Ent-Kaurene Diterpenoid Oridonin as an E3 Ligase Recruiter for PROTACs.
Jie Huang, Xuekun Fu, Fang Qiu, Zhijian Liang, Chunhao Cao

J Am Chem Soc· January 2025

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Development of dual aptamers-functionalized c-MET PROTAC degraders for targeted therapy of osteosarcoma.
Xuekun Fu, Jie Huang, Xinxin Chen, Duoli Xie, Hongzhen Chen

Theranostics· January 2025

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Repurposing AS1411 for constructing ANM-PROTACs.
Xuekun Fu, Jin Li, Xinxin Chen, Hongzhen Chen, Zhuqian Wang

Cell Chem Biol· July 2024

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Gut microbial metabolite targets HDAC3-FOXK1-interferon axis in fibroblast-like synoviocytes to ameliorate rheumatoid arthritis.
Hongzhen Chen, Xuekun Fu, Xiaohao Wu, Junyi Zhao, Fang Qiu

Bone Res· May 2024

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Poly (ADP-ribose) polymerase 1 (PARP1) inhibition promotes pulmonary metastasis of osteosarcoma by boosting ezrin phosphorylation.
Fangfei Li, Xiaoqiu Wu, Xuekun Fu, Jin Liu, Wangze Song

Int J Biol Sci· April 2022

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Kindlin-2 preserves integrity of the articular cartilage to protect against osteoarthritis.
Xiaohao Wu, Yumei Lai, Sheng Chen, Chunlei Zhou, Chu Tao, Xuekun Fu

Nat Aging· April 2022

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Andrographolide prevents bone loss via targeting estrogen-related receptor-α-regulated metabolic adaption of osteoclastogenesis.
Tongling Huang, Xuekun Fu, Na Wang, Meng Yang, Minyi Zhang

Br J Pharmacol· November 2021

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Promising Therapeutic Targets for Treatment of Rheumatoid Arthritis.
Jie Huang, Xuekun Fu, Xinxin Chen, Zheng Li, Yuhong Huang

Front Immunol· October 2021

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Advances in Screening and Development of Therapeutic Aptamers Against Cancer Cells.
Zheng Li, Xuekun Fu, Jie Huang, Peiyuan Zeng, Yuhong Huang

Front Cell Dev Biol· May 2021

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Kindlin-2 mediates mechanotransduction in bone by regulating expression of Sclerostin in osteocytes.
Lei Qin, Xuekun Fu, Jing Ma, Manxia Lin, Peijun Zhang

Commun Biol· March 2021

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Advances in Aptamer-Based Biomarker Discovery.
Jie Huang, Xinxin Chen, Xuekun Fu, Zheng Li, Yuhong Huang

Front Cell Dev Biol· March 2021

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gene silencing prevents colorectal cancer progression via suppressing Sonic Hedgehog (SHH) signaling pathway.
Shasha Chen, Bin Wang, Xuekun Fu, Yanfang Liang, Xingxing Chai

J Cancer· January 2021

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Kindlin-2 regulates skeletal homeostasis by modulating PTH1R in mice.
Xuekun Fu, Bo Zhou, Qinnan Yan, Chu Tao, Lei Qin

Signal Transduct Target Ther· December 2020

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LIM domain proteins Pinch1/2 regulate chondrogenesis and bone mass in mice.
Yiming Lei, Xuekun Fu, Pengyu Li, Sixiong Lin, Qinnan Yan

Bone Res· October 2020

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Moderate Fluid Shear Stress Regulates Heme Oxygenase-1 Expression to Promote Autophagy and ECM Homeostasis in the Nucleus Pulposus Cells.
Sheng Chen, Lei Qin, Xiaohao Wu, Xuekun Fu, Sixiong Lin

Front Cell Dev Biol· March 2020

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The Rules and Functions of Nucleocytoplasmic Shuttling Proteins.
Xuekun Fu, Chao Liang, Fangfei Li, Luyao Wang, Xiaoqiu Wu

Int J Mol Sci· May 2018

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Runx2/Osterix and Zinc Uptake Synergize to Orchestrate Osteogenic Differentiation and Citrate Containing Bone Apatite Formation.
Xuekun Fu, Yunyan Li, Tongling Huang, Zhiwu Yu, Kun Ma

Adv Sci (Weinh)· April 2018

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Ginsenoside Rg1 protects rat bone marrow mesenchymal stem cells against ischemia induced apoptosis through miR-494-3p and ROCK-1.
Hui-Zhen Zheng, Xue-Kun Fu, Jiu-Long Shang, Rong-Xi Lu, Yong-Fang Ou

Eur J Pharmacol· March 2018

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PARP1 in Carcinomas and PARP1 Inhibitors as Antineoplastic Drugs.
Luyao Wang, Chao Liang, Fangfei Li, Daogang Guan, Xiaoqiu Wu, Xuekun Fu

Int J Mol Sci· October 2017

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Aging Reduces an ERRalpha-Directed Mitochondrial Glutaminase Expression Suppressing Glutamine Anaplerosis and Osteogenic Differentiation of Mesenchymal Stem Cells.
Tongling Huang, Renzhong Liu, Xuekun Fu, Dongsheng Yao, Meng Yang

Stem Cells· February 2017

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