Publications by authors named "Patrick Schnider"

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Selective and brain-penetrant HCN1 inhibitors reveal links between synaptic integration, cortical function, and working memory.
Eva Harde, Markus Hierl, Michael Weber, David Waiz, Roger Wyler, Patrick Schnider

Cell Chem Biol· March 2024

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Selective oxytocin receptor activation prevents prefrontal circuit dysfunction and social behavioral alterations in response to chronic prefrontal cortex activation in male rats.
Philipp Janz, Frederic Knoflach, Konrad Bleicher, Sara Belli, Barbara Biemans, Patrick Schnider

Front Cell Neurosci· December 2023

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Perfect Matchings with Crossings.
Oswin Aichholzer, Ruy Fabila-Monroy, Philipp Kindermann, Irene Parada, Rosna Paul, Patrick Schnider

Algorithmica· July 2023

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Arrangements of Approaching Pseudo-Lines.
Stefan Felsner, Alexander Pilz, Patrick Schnider

Discrete Comput Geom· January 2022

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Discovery of Balovaptan, a Vasopressin 1a Receptor Antagonist for the Treatment of Autism Spectrum Disorder.
Patrick Schnider, Caterina Bissantz, Andreas Bruns, Cosimo Dolente, Erwin Goetschi

J Med Chem· February 2020

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Modulation of Pharmacologically Relevant Properties of Piperidine Derivatives by Functional Groups in an Equatorial or Axial β-Position to the Amino Group.
Patrick Schnider, Cosimo Dolente, Henri Stalder, Rainer E Martin, Viktoria Reinmüller

Chembiochem· January 2020

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From receptor binding kinetics to signal transduction; a missing link in predicting in vivo drug-action.
Indira Nederpelt, Maria Kuzikov, Wilbert E A de Witte, Patrick Schnider, Bruno Tuijt

Sci Rep· October 2017

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Discovery of highly selective brain-penetrant vasopressin 1a antagonists for the potential treatment of autism via a chemogenomic and scaffold hopping approach.
Hasane Ratni, Mark Rogers-Evans, Caterina Bissantz, Christophe Grundschober, Jean-Luc Moreau, Patrick Schnider

J Med Chem· March 2015

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Identification of a crucial amino acid in the helix position 6.51 of human tachykinin neurokinin 1 and 3 receptors contributing to the insurmountable mode of antagonism by dual NK₁/NK₃ antagonists.
Caterina Bissantz, Claudia Bohnert, Torsten Hoffmann, Anne Marcuz, Patrick Schnider

J Med Chem· June 2012

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ROCK: the Roche medicinal chemistry knowledge application - design, use and impact.
Alexander Mayweg, Urs Hofer, Patrick Schnider, Fausto Agnetti, Guido Galley

Drug Discov Today· August 2011

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Discovery of potent, balanced and orally active dual NK1/NK3 receptor ligands.
Jens-Uwe Peters, Torsten Hoffmann, Patrick Schnider, Heinz Stadler, Andreas Koblet

Bioorg Med Chem Lett· June 2010

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The importance of width/length ratios of maxillary anterior permanent teeth in esthetic rehabilitation.
Sillas Duarte, Patrick Schnider, Ana Paula Lorezon

Eur J Esthet Dent· August 2009

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Pharmacological promiscuity: dependence on compound properties and target specificity in a set of recent Roche compounds.
Jens-Uwe Peters, Patrick Schnider, Patrizio Mattei, Manfred Kansy

ChemMedChem· April 2009

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Design and synthesis of a novel, achiral class of highly potent and selective, orally active neurokinin-1 receptor antagonists.
Torsten Hoffmann, Michael Bös, Heinz Stadler, Patrick Schnider, Walter Hunkeler

Bioorg Med Chem Lett· March 2006

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Greatly Simplified Procedures for the Synthesis of alpha-Amino Acids by the Direct Alkylation of Pseudoephedrine Glycinamide Hydrate.
Andrew G. Myers, Patrick Schnider, Soojin Kwon, Daniel W. Kung

J Org Chem· April 1999

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Enantioselective Hydrogenation of Olefins with Iridium-Phosphanodihydrooxazole Catalysts.
Andrew Lightfoot, Patrick Schnider, Andreas Pfaltz

Angew Chem Int Ed Engl· November 1998

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