Publications by authors named "Patrick Woster"

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Micro-Computed Tomography Analysis of the Knee in Aged Dunkin-Hartley Guinea Pigs after Intra Articular Injection.
Jen X Xu, Frank Z Xu, Amelia Furbish, Yuri K Peterson, Patrick M Woster

J Vis Exp· August 2024

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Establishing New Isosexual Pairs in Adult Male Guinea Pigs () to Facilitate Social Housing.
Jen X Xu, Ashton Coker, Zadie Dulaney, Amelia Furbish, Frank Z Xu, Patrick M Woster

J Am Assoc Lab Anim Sci· March 2024

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Stimulation of natural killer cells with small molecule inhibitors of CD38 for the treatment of neuroblastoma.
Catherine M Mills, Thomas Z Benton, Ivett Piña, Megan J Francis, Leticia Reyes, Patrick M Woster

Chem Sci· February 2023

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Synthesis and evaluation of small molecule inhibitors of LSD1 for use against MYCN-expressing neuroblastoma.
Catherine M Mills, Jonathan Turner, Ivett C Piña, Kathleen A Garrabrant, Dirk Geerts, Patrick M Woster

Eur J Med Chem· December 2022

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Mitochondrial depolarization after acute ethanol treatment drives mitophagy in living mice.
Devadoss J Samuvel, Li Li, Yasodha Krishnasamy, Monika Gooz, Kenji Takemoto, Patrick M Woster

Autophagy· November 2022

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New Transmission-Selective Antimalarial Agents through Hit-to-Lead Optimization of 2-([1,1'-Biphenyl]-4-carboxamido)benzoic Acid Derivatives.
Janette Reader, Daniel F L Opperman, Mariëtte E van der Watt, Anjo Theron, Meta Leshabane, Patrick M Woster

Chembiochem· November 2022

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Identification and Characterization of Novel Small-Molecule SMOX Inhibitors.
Amelia B Furbish, Ahmed S Alford, Pieter Burger, Yuri K Peterson, Tracy Murray-Stewart, Patrick M Woster

Med Sci (Basel)· August 2022

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The biguanide polyamine analog verlindamycin promotes differentiation in neuroblastoma via induction of antizyme.
Zuzanna Urban-Wójciuk, Amy Graham, Karen Barker, Colin Kwok, Yordan Sbirkov, Patrick M Woster

Cancer Gene Ther· July 2022

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Small molecules targeting the NADH-binding pocket of VDAC modulate mitochondrial metabolism in hepatocarcinoma cells.
Kareem A Heslop, Pieter Burger, Christiana Kappler, Ashish K Solanki, Monika Gooz, Patrick M Woster

Biomed Pharmacother· June 2022

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Application of Pharmacokinetic Prediction Platforms in the Design of Optimized Anti-Cancer Drugs.
Tyler C Beck, Kendra Springs, Jordan E Morningstar, Catherine Mills, Andrew Stoddard, Patrick Woster

Molecules· June 2022

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Inhibition of Polyamine Biosynthesis Using Difluoromethylornithine Acts as a Potent Immune Modulator and Displays Therapeutic Synergy With PD-1-blockade.
Parker Dryja, Carrie Fisher, Patrick M Woster, Eric Bartee

J Immunother· October 2021

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Selective targeting of CD38 hydrolase and cyclase activity as an approach to immunostimulation.
Thomas Z Benton, Catherine M Mills, Jonathan M Turner, Megan J Francis, Dalan J Solomon, Patrick M Woster

RSC Adv· October 2021

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Epigenetic Reexpression of Hemoglobin F Using Reversible LSD1 Inhibitors: Potential Therapies for Sickle Cell Disease.
Steven Holshouser, Rebecca Cafiero, Mayra Robinson, Joy Kirkpatrick, Robert A Casero, Patrick M Woster

ACS Omega· June 2020

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Spermine oxidase mediates Helicobacter pylori-induced gastric inflammation, DNA damage, and carcinogenic signaling.
Johanna C Sierra, M Blanca Piazuelo, Paula B Luis, Daniel P Barry, Margaret M Allaman, Patrick M Woster

Oncogene· May 2020

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Novel Synthetic Polyamines Have Potent Antimalarial Activities and by Decreasing Intracellular Spermidine and Spermine Concentrations.
Kamal El Bissati, Henry Redel, Li-Min Ting, Joseph D Lykins, Martin J McPhillie, Patrick M Woster

Front Cell Infect Microbiol· December 2019

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Aldehyde dehydrogenase-2 activation by Alda-1 decreases necrosis and fibrosis after bile duct ligation in mice.
Hereward J Wimborne, Kenji Takemoto, Patrick M Woster, Don C Rockey, John J Lemasters

Free Radic Biol Med· December 2019

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Citizenship in the World of Medicinal Chemistry: 25 Years as an ACSMEDI Volunteer.
Patrick M Woster

ACS Med Chem Lett· May 2019

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Dual inhibitors of LSD1 and spermine oxidase.
Steven Holshouser, Matthew Dunworth, Tracy Murray-Stewart, Yuri K Peterson, Pieter Burger, Patrick M Woster

Medchemcomm· May 2019

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Inhibition of the histone demethylase KDM4B leads to activation of KDM1A, attenuates bacterial-induced pro-inflammatory cytokine release, and reduces osteoclastogenesis.
Joy E Kirkpatrick, Keith L Kirkwood, Patrick M Woster

Epigenetics· February 2019

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Curcumin mediates polyamine metabolism and sensitizes gastrointestinal cancer cells to antitumor polyamine-targeted therapies.
Tracy Murray-Stewart, Matthew Dunworth, Yuan Lui, Francis M Giardiello, Patrick M Woster

PLoS One· February 2019

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Polyamine catabolism and oxidative damage.
Tracy Murray Stewart, Tiffany T Dunston, Patrick M Woster, Robert A Casero

J Biol Chem· November 2018

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Corrigendum to "Structure-activity study for (bis)ureidopropyl- and (bis)thioureidopropyldiamine LSD1 inhibitors with 3-5-3 and 3-6-3 carbon backbone architectures" [Bioorg. Med. Chem. 23 (2015) 1601-1612].
Shannon L Nowotarski, Boobalan Pachaiyappan, Steven L Holshouser, Craig J Kutz, Youxuan Li, Patrick M Woster

Bioorg Med Chem· July 2018

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Cyclic peptide inhibitors of lysine-specific demethylase 1 with improved potency identified by alanine scanning mutagenesis.
Isuru R Kumarasinghe, Patrick M Woster

Eur J Med Chem· March 2018

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Targeting polyamine metabolism for cancer therapy and prevention.
Tracy R Murray-Stewart, Patrick M Woster, Robert A Casero

Biochem J· October 2016

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Antibacterial Diamines Targeting Bacterial Membranes.
Bo Wang, Boobalan Pachaiyappan, Jordon D Gruber, Michael G Schmidt, Yong-Mei Zhang, Patrick M Woster

J Med Chem· April 2016

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