Publications by authors named "Paul D Carr"

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Author Correction: Higher-order epistasis shapes the fitness landscape of a xenobiotic-degrading enzyme.
Gloria Yang, Dave W Anderson, Florian Baier, Elias Dohmen, Nansook Hong, Paul D Carr

Nat Chem Biol· August 2020

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Higher-order epistasis shapes the fitness landscape of a xenobiotic-degrading enzyme.
Gloria Yang, Dave W Anderson, Florian Baier, Elias Dohmen, Nansook Hong, Paul D Carr

Nat Chem Biol· November 2019

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FAD-sequestering proteins protect mycobacteria against hypoxic and oxidative stress.
Liam K Harold, James Antoney, F Hafna Ahmed, Kiel Hards, Paul D Carr

J Biol Chem· February 2019

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Cryptic genetic variation shapes the adaptive evolutionary potential of enzymes.
Florian Baier, Nansook Hong, Gloria Yang, Anna Pabis, Charlotte M Miton, Paul D Carr

Elife· February 2019

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The evolution of multiple active site configurations in a designed enzyme.
Nan-Sook Hong, Dušan Petrović, Richmond Lee, Ganna Gryn'ova, Miha Purg, Paul D Carr

Nat Commun· September 2018

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Mechanistic Basis of pH-Dependent 5-Flucytosine Resistance in Aspergillus fumigatus.
Fabio Gsaller, Takanori Furukawa, Paul D Carr, Bharat Rash, Christoph Jöchl

Antimicrob Agents Chemother· June 2018

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Evolution of cyclohexadienyl dehydratase from an ancestral solute-binding protein.
Ben E Clifton, Joe A Kaczmarski, Paul D Carr, Monica L Gerth, Nobuhiko Tokuriki

Nat Chem Biol· June 2018

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Synthesis, X-ray Structural Characterization, and DFT Calculations of Mononuclear Nickel(II) Complexes Containing Diamine and Methacrylate Ligands.
Rasoul Vafazadeh, Mansoor Namazian, Behnoosh Shahpoori-Arani, Anthony C Willis, Paul D Carr

Acta Chim Slov· June 2018

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Palladium-Catalyzed Ullmann Cross-Coupling of β-Iodoenones and β-Iodoacrylates with o-Halonitroarenes or o-Iodobenzonitriles and Reductive Cyclization of the Resulting Products To Give Diverse Heterocyclic Systems.
Faiyaz Khan, Michael Dlugosch, Xin Liu, Marium Khan, Martin G Banwell, Paul D Carr

Org Lett· May 2018

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Structure of an Insecticide Sequestering Carboxylesterase from the Disease Vector Culex quinquefasciatus: What Makes an Enzyme a Good Insecticide Sponge?
Davis H Hopkins, Nicholas J Fraser, Peter D Mabbitt, Paul D Carr, John G Oakeshott

Biochemistry· October 2017

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The Synthesis of Certain Derivatives and Analogues of (-)- and (+)-Galanthamine and an Assessment of their Capacities to Inhibit Acetylcholine Esterase.
Joshua N Buckler, Ehab S Taher, Nicolas J Fraser, Anthony C Willis, Paul D Carr

J Org Chem· August 2017

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Studies on the Photochemical Rearrangements of Enantiomerically Pure, Polysubstituted, and Variously Annulated Bicyclo[2.2.2]octenones.
Qiao Yan, Benoit Bolte, Yuhua Bai, Martin G Banwell, Anthony C Willis, Paul D Carr

J Org Chem· August 2017

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Total Synthesis of the Cyclic Carbonate-Containing Natural Product Aspergillusol B from d-(-)-Tartaric Acid.
Joshua N Buckler, Tamaryn Meek, Martin G Banwell, Paul D Carr

J Nat Prod· July 2017

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A Palladium-Catalyzed Ullmann Cross-Coupling/Reductive Cyclization Route to the Carbazole Natural Products 3-Methyl-9H-carbazole, Glycoborine, Glycozoline, Clauszoline K, Mukonine, and Karapinchamine A.
Qiao Yan, Emma Gin, Malgorzata Wasinska-Kalwa, Martin G Banwell, Paul D Carr

J Org Chem· April 2017

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A Unified Approach to the Isomeric α-, β-, γ-, and δ-Carbolines via their 6,7,8,9-Tetrahydro Counterparts.
Qiao Yan, Emma Gin, Martin G Banwell, Anthony C Willis, Paul D Carr

J Org Chem· April 2017

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A Total Synthesis of (±)-3-O-Demethylmacronine through Rearrangement of a Precursor Embodying the Haemanthidine Alkaloid Framework.
Xiang Ma, Nadia Gao, Martin G Banwell, Paul D Carr, Anthony C Willis

J Org Chem· April 2017

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Correction: Sterol Biosynthesis and Azole Tolerance Is Governed by the Opposing Actions of SrbA and the CCAAT Binding Complex.
Fabio Gsaller, Peter Hortschansky, Takanori Furukawa, Paul D Carr, Bharat Rash

PLoS Pathog· December 2016

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The role of protein dynamics in the evolution of new enzyme function.
Eleanor Campbell, Miriam Kaltenbach, Galen J Correy, Paul D Carr, Benjamin T Porebski

Nat Chem Biol· November 2016

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Active Site Desolvation and Thermostability Trade-Offs in the Evolution of Catalytically Diverse Triazine Hydrolases.
Elena Sugrue, Paul D Carr, Colin Scott, Colin J Jackson

Biochemistry· November 2016

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Rv2074 is a novel F420 H2 -dependent biliverdin reductase in Mycobacterium tuberculosis.
F Hafna Ahmed, A Elaaf Mohamed, Paul D Carr, Brendon M Lee, Karmen Condic-Jurkic

Protein Sci· September 2016

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Sterol Biosynthesis and Azole Tolerance Is Governed by the Opposing Actions of SrbA and the CCAAT Binding Complex.
Fabio Gsaller, Peter Hortschansky, Takanori Furukawa, Paul D Carr, Bharat Rash

PLoS Pathog· July 2016

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Mapping the Accessible Conformational Landscape of an Insect Carboxylesterase Using Conformational Ensemble Analysis and Kinetic Crystallography.
Galen J Correy, Paul D Carr, Tamara Meirelles, Peter D Mabbitt, Nicholas J Fraser

Structure· June 2016

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Modular Total Syntheses of the Alkaloids Discoipyrroles A and B, Potent Inhibitors of the DDR2 Signaling Pathway.
Yiwen Zhang, Martin G Banwell, Paul D Carr, Anthony C Willis

Org Lett· February 2016

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Sequence-Structure-Function Classification of a Catalytically Diverse Oxidoreductase Superfamily in Mycobacteria.
F Hafna Ahmed, Paul D Carr, Brendon M Lee, Livnat Afriat-Jurnou, A Elaaf Mohamed

J Mol Biol· November 2015

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Evolutionary expansion of the amidohydrolase superfamily in bacteria in response to the synthetic compounds molinate and diuron.
Elena Sugrue, Nicholas J Fraser, Davis H Hopkins, Paul D Carr, Jeevan L Khurana

Appl Environ Microbiol· April 2015

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