Publications by authors named "Paul Gilson"

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Deconvolution of the On-Target Activity of Plasmepsin V Peptidomimetics in Parasites.
Wenyin Su, William Nguyen, Ghizal Siddiqui, Jerzy M Dziekan, Danushka Marapana, Paul R Gilson

ACS Infect Dis· December 2025

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Optimization and Characterization of the Antimalarial Activity of -Aryl Acetamides that are Susceptible to Mutations in ROM8 and CSC1.
William Nguyen, Coralie Boulet, Madeline G Dans, Katie Loi, Kate E Jarman, Paul R Gilson

J Med Chem· August 2025

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Author Correction: Aryl amino acetamides prevent Plasmodium falciparum ring development via targeting the lipid-transfer protein PfSTART1.
Madeline G Dans, Coralie Boulet, Gabrielle M Watson, William Nguyen, Jerzy M Dziekan, Paul R Gilson

Nat Commun· September 2024

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Aryl amino acetamides prevent Plasmodium falciparum ring development via targeting the lipid-transfer protein PfSTART1.
Madeline G Dans, Coralie Boulet, Gabrielle M Watson, William Nguyen, Jerzy M Dziekan, Paul R Gilson

Nat Commun· June 2024

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Activity refinement of aryl amino acetamides that target the P. falciparum STAR-related lipid transfer 1 protein.
William Nguyen, Coralie Boulet, Madeline G Dans, Katie Loi, Kate E Jarman, Paul R Gilson

Eur J Med Chem· April 2024

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Sequence elements within the PEXEL motif and its downstream region modulate PTEX-dependent protein export in Plasmodium falciparum.
Mikha Gabriela, Claudia B G Barnes, Dickson Leong, Brad E Sleebs, Molly Parkyn Schneider, Paul R Gilson

Traffic· January 2024

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Dissecting EXP2 sequence requirements for protein export in malaria parasites.
Ethan L Pitman, Natalie A Counihan, Joyanta K Modak, Mrittika Chowdury, Paul R Gilson

Front Cell Infect Microbiol· January 2024

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Bottoms up! Malaria parasite invasion the right way around.
Mia Andrews, Jake Baum, Paul R Gilson, Danny W Wilson

Trends Parasitol· December 2023

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Conditional expression of NanoLuc luciferase through a multimodular system offers rapid detection of antimalarial drug activity.
Caroline Lima, Ignasi B Verdaguer, Gerhard Wunderlich, Alejandro M Katzin, Brendan S Crabb, Paul R Gilson

Exp Parasitol· November 2023

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A Pyridyl-Furan Series Developed from the Open Global Health Library Block Red Blood Cell Invasion and Protein Trafficking in through Potential Inhibition of the Parasite's PI4KIIIB Enzyme.
Dawson B Ling, William Nguyen, Oliver Looker, Zahra Razook, Kirsty McCann, Paul R Gilson

ACS Infect Dis· September 2023

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The dual action of human antibodies specific to Plasmodium falciparum PfRH5 and PfCyRPA: Blocking invasion and inactivating extracellular merozoites.
Greta E Weiss, Robert J Ragotte, Doris Quinkert, Amelia M Lias, Madeline G Dans, Paul R Gilson

PLoS Pathog· September 2023

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Plasmodium falciparum formins are essential for invasion and sexual stage development.
Sophie Collier, Emma Pietsch, Madeline Dans, Dawson Ling, Tatyana A Tavella, Paul Gilson

Commun Biol· August 2023

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The delayed bloodstream clearance of parasites after M5717 treatment is attributable to the inability to modify their red blood cell hosts.
Molly Parkyn Schneider, Oliver Looker, Maria Rebelo, David S Khoury, Matthew W A Dixon, Paul R Gilson

Front Cell Infect Microbiol· July 2023

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PTEX helps efficiently traffic haemoglobinases to the food vacuole in Plasmodium falciparum.
Thorey K Jonsdottir, Brendan Elsworth, Simon Cobbold, Mikha Gabriela, Ellen Ploeger, Paul R Gilson

PLoS Pathog· July 2023

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Sulfonylpiperazine compounds prevent Plasmodium falciparum invasion of red blood cells through interference with actin-1/profilin dynamics.
Madeline G Dans, Henni Piirainen, William Nguyen, Sachin Khurana, Somya Mehra, Paul R Gilson

PLoS Biol· April 2023

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Defining species-specific and conserved interactions of apical membrane protein 1 during erythrocyte invasion in malaria to inform multi-species vaccines.
Damien R Drew, Danny W Wilson, Gretchen E Weiss, Lee M Yeoh, Isabelle G Henshall, Paul R Gilson

Cell Mol Life Sci· February 2023

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Characterisation of PfCZIF1 and PfCZIF2 in Plasmodium falciparum asexual stages.
Juan M Balbin, Gary K Heinemann, Lee M Yeoh, Tim-Wolf Gilberger, Mark Armstrong, Paul R Gilson

Int J Parasitol· January 2023

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ATP4 inhibitors in the Medicines for Malaria Venture Malaria Box and Pathogen Box block the schizont-to-ring transition by inhibiting egress rather than invasion.
Claudia B G Barnes, Madeline G Dans, Thorey K Jonsdottir, Brendan S Crabb, Paul R Gilson

Front Cell Infect Microbiol· December 2022

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The Medicines for Malaria Venture Malaria Box contains inhibitors of protein secretion in Plasmodium falciparum blood stage parasites.
Oliver Looker, Madeline G Dans, Hayley E Bullen, Brad E Sleebs, Brendan S Crabb, Paul R Gilson

Traffic· September 2022

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The Plasmodium falciparum parasitophorous vacuole protein P113 interacts with the parasite protein export machinery and maintains normal vacuole architecture.
Hayley E Bullen, Paul R Sanders, Madeline G Dans, Thorey K Jonsdottir, David T Riglar, Paul R Gilson

Mol Microbiol· May 2022

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A revised mechanism for how Plasmodium falciparum recruits and exports proteins into its erythrocytic host cell.
Mikha Gabriela, Kathryn M Matthews, Cas Boshoven, Betty Kouskousis, Thorey K Jonsdottir, Paul R Gilson

PLoS Pathog· February 2022

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Structure of the Pf12 and Pf41 heterodimeric complex of 6-cysteine proteins.
Melanie H Dietrich, Li-Jin Chan, Amy Adair, Coralie Boulet, Matthew T O'Neill, Paul Gilson

FEMS Microbes· February 2022

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Property activity refinement of 2-anilino 4-amino substituted quinazolines as antimalarials with fast acting asexual parasite activity.
Trent D Ashton, Anna Ngo, Paola Favuzza, Hayley E Bullen, Maria R Gancheva, Paul R Gilson

Bioorg Chem· December 2021

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The Role of Malaria Parasite Heat Shock Proteins in Protein Trafficking and Remodelling of Red Blood Cells.
Thorey K Jonsdottir, Mikha Gabriela, Paul R Gilson

Adv Exp Med Biol· September 2021

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Defining the Essential Exportome of the Malaria Parasite.
Thorey K Jonsdottir, Mikha Gabriela, Brendan S Crabb, Tania F de Koning-Ward, Paul R Gilson

Trends Parasitol· July 2021

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