Publications by authors named "Paul Hessler"

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Selective Inhibition of the Second Bromodomain of BET Family Proteins Results in Robust Antitumor Activity in Preclinical Models of Acute Myeloid Leukemia.
Lu Zhang, Tianyu Cai, Xiaoyu Lin, Xiaoli Huang, Mai H Bui, Paul Hessler

Mol Cancer Ther· October 2021

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Selective inhibition of the BD2 bromodomain of BET proteins in prostate cancer.
Emily J Faivre, Keith F McDaniel, Daniel H Albert, Srinivasa R Mantena, Joshua P Plotnik, Paul Hessler

Nature· February 2020

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Targeting Lineage-specific MITF Pathway in Human Melanoma Cell Lines by A-485, the Selective Small-molecule Inhibitor of p300/CBP.
Rui Wang, Yupeng He, Valerie Robinson, Ziping Yang, Paul Hessler

Mol Cancer Ther· December 2018

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Author Correction: Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours.
Loren M Lasko, Clarissa G Jakob, Rohinton P Edalji, Wei Qiu, Debra Montgomery, Paul Hessler

Nature· June 2018

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Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours.
Loren M Lasko, Clarissa G Jakob, Rohinton P Edalji, Wei Qiu, Debra Montgomery, Paul Hessler

Nature· October 2017

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The Volume of Three-Dimensional Cultures of Cancer Cells InVitro Influences Transcriptional Profile Differences and Similarities with Monolayer Cultures and Xenografted Tumors.
Erwin R Boghaert, Xin Lu, Paul E Hessler, Thomas P McGonigal, Anatol Oleksijew

Neoplasia· September 2017

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Potential mechanisms of resistance to venetoclax and strategies to circumvent it.
Stephen K Tahir, Morey L Smith, Paul Hessler, Lisa Roberts Rapp, Kenneth B Idler

BMC Cancer· June 2017

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HEXIM1 as a Robust Pharmacodynamic Marker for Monitoring Target Engagement of BET Family Bromodomain Inhibitors in Tumors and Surrogate Tissues.
Xiaoyu Lin, Xiaoli Huang, Tamar Uziel, Paul Hessler, Daniel H Albert

Mol Cancer Ther· February 2017

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Exploitation of Castration-Resistant Prostate Cancer Transcription Factor Dependencies by the Novel BET Inhibitor ABBV-075.
Emily J Faivre, Denise Wilcox, Xiaoyu Lin, Paul Hessler, Maricel Torrent

Mol Cancer Res· January 2017

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MCL-1 Is a Key Determinant of Breast Cancer Cell Survival: Validation of MCL-1 Dependency Utilizing a Highly Selective Small Molecule Inhibitor.
Yu Xiao, Paul Nimmer, George S Sheppard, Milan Bruncko, Paul Hessler

Mol Cancer Ther· August 2015

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Genomic analysis and selective small molecule inhibition identifies BCL-X(L) as a critical survival factor in a subset of colorectal cancer.
Haichao Zhang, John Xue, Paul Hessler, Stephen K Tahir, Jun Chen

Mol Cancer· July 2015

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Identification of expression signatures predictive of sensitivity to the Bcl-2 family member inhibitor ABT-263 in small cell lung carcinoma and leukemia/lymphoma cell lines.
Stephen K Tahir, John Wass, Mary K Joseph, Viswanath Devanarayan, Paul Hessler

Mol Cancer Ther· March 2010

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Akt inhibitor a-443654 interferes with mitotic progression by regulating aurora a kinase expression.
Xuesong Liu, Yan Shi, Keith W Woods, Paul Hessler, Paul Kroeger

Neoplasia· August 2008

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Protein tyrosine phosphatase 1B negatively regulates leptin signaling in a hypothalamic cell line.
Wiweka Kaszubska, H Douglas Falls, Verlyn G Schaefer, Deanna Haasch, Leigh Frost, Paul Hessler

Mol Cell Endocrinol· September 2002

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