Publications by authors named "Paul Leger"

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A multi-perspective study assessing Black and African American participation barriers in prostate cancer clinical trials.
Paul Leger, Stanley Frencher, Jones T Nauseef, Brian Jones, Mehmet A Bilen

Future Oncol· April 2025

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Maintenance of patient-reported health-related quality of life post neoadjuvant relugolix prior to the initiation of prostate radiation therapy.
Min Jung Koh, Min Ji Koh, Jessica Y Hsueh, Lindsey Gallagher, Malika Danner, Paul Leger

Front Oncol· January 2025

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Utilization of patient-reported outcomes to assess adherence to relugolix when combined with stereotactic body radiation therapy for intermediate to high-risk prostate cancer.
Kelly Gaudian, Min Jung Koh, Min Ji Koh, Ryan R Collins, Shaine Eden, Paul Leger

Front Oncol· January 2025

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The impact of neoadjuvant relugolix on multi-dimensional patient-reported fatigue.
Jessica Y Hsueh, Lindsey Gallagher, Min Ji Koh, Sarthak Shah, Malika Danner, Paul Leger

Front Oncol· August 2024

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Impact of neoadjuvant relugolix on patient-reported sexual function and bother.
Jessica Y Hsueh, Lindsey Gallagher, Min Ji Koh, Shaine Eden, Sarthak Shah, Paul Leger

Front Oncol· April 2024

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Bothersome Hot Flashes Following Neoadjuvant Androgen Deprivation Therapy and Stereotactic Body Radiotherapy for Localized Prostate Cancer.
Sarthak Shah, Abigail Pepin, Simran Jatar, Jessica Hsueh, Lindsey Gallagher, Paul D Leger

Cureus· March 2024

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Early biochemical outcomes following neoadjuvant/adjuvant relugolix with stereotactic body radiation therapy for intermediate to high risk prostate cancer.
Lindsey Gallagher, Jerry Xiao, Jessica Hsueh, Sarthak Shah, Malika Danner, Paul Leger

Front Oncol· October 2023

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Benefits, challenges, and usability evaluation of DeloreanJS: a back-in-time debugger for JavaScript.
Paul Leger, Felipe Ruiz, Hiroaki Fukuda, Nicolás Cardozo

PeerJ Comput Sci· February 2023

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Potent GCN2 Inhibitor Capable of Reversing MDSC-Driven T Cell Suppression Demonstrates In Vivo Efficacy as a Single Agent and in Combination with Anti-Angiogenesis Therapy.
Jeffrey J Jackson, Grant M Shibuya, Buvana Ravishankar, Lavanya Adusumilli, Delia Bradford, Paul R Leger

J Med Chem· October 2022

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DSSM: Distributed Streaming Data Sharing Manager.
Hiroaki Fukuda, Ryota Gunji, Tadahiro Hasegawa, Paul Leger, Ismael Figueroa

Sensors (Basel)· February 2021

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Rationale for Involved Field Stereotactic Body Radiation Therapy-Enhanced Intermittent Androgen Deprivation Therapy in Hormone-Sensitive Nodal Oligo-Recurrent Prostate Cancer Following Prostate Stereotactic Body Radiation Therapy.
Michael Carrasquilla, Michael L Creswell, Abigail N Pepin, Edina Wang, Matthew Forsthoefel, Paul Leger

Front Oncol· January 2021

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Novel, Selective Inhibitors of USP7 Uncover Multiple Mechanisms of Antitumor Activity and .
Yamini M Ohol, Michael T Sun, Gene Cutler, Paul R Leger, Dennis X Hu

Mol Cancer Ther· October 2020

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C-C Bond Cleavage Approach to Complex Terpenoids: Development of a Unified Total Synthesis of the Phomactins.
Paul R Leger, Yusuke Kuroda, Stanley Chang, Justin Jurczyk, Richmond Sarpong

J Am Chem Soc· September 2020

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drives chemoresistance in small cell lung cancer while USP7 inhibition can restore chemosensitivity.
Eli Grunblatt, Nan Wu, Huajia Zhang, Xiaoli Liu, Justin P Norton, Paul Leger

Genes Dev· September 2020

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Discovery of Potent, Selective, and Orally Bioavailable Inhibitors of USP7 with In Vivo Antitumor Activity.
Paul R Leger, Dennis X Hu, Berenger Biannic, Minna Bui, Xinping Han

J Med Chem· May 2020

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Isolation, synthesis and bioactivity studies of phomactin terpenoids.
Yusuke Kuroda, Karen J Nicacio, Ildefonso Alves da Silva-Jr, Paul R Leger, Stanley Chang

Nat Chem· September 2018

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Race/ethnicity difference in the pharmacogenetics of bilirubin-related atazanavir discontinuation.
Paul Leger, Sanika Chirwa, Jacinta N Nwogu, Megan Turner, Danielle M Richardson

Pharmacogenet Genomics· January 2018

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Risk factors for early mortality on antiretroviral therapy in advanced HIV-infected adults.
Gregory P Bisson, Ritesh Ramchandani, Sachiko Miyahara, Rosie Mngqibisa, Mitch Matoga, Paul Leger

AIDS· October 2017

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A Case Report of Severe Type B Lactic Acidosis Following First Dose of Nivolumab in a VHL-Mutated Metastatic Renal Cell Carcinoma.
Erica Nakajima, Paul Leger, Ingrid A Mayer, Michael N Neuss, David D Chism

Kidney Cancer· July 2017

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Pulmonary Toxicities from Conventional Chemotherapy.
Paul Leger, Andrew H Limper, Fabien Maldonado

Clin Chest Med· June 2017

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Clinical Features of Acquired Resistance to Anti-PD-1 Therapy in Advanced Melanoma.
Daniel Y Wang, Zeynep Eroglu, Alpaslan Ozgun, Paul D Leger, Shilin Zhao

Cancer Immunol Res· May 2017

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Pharmacogenetics of efavirenz discontinuation for reported central nervous system symptoms appears to differ by race.
Paul Leger, Sanika Chirwa, Megan Turner, Danielle M Richardson, Paxton Baker

Pharmacogenet Genomics· October 2016

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Empirical tuberculosis therapy versus isoniazid in adult outpatients with advanced HIV initiating antiretroviral therapy (REMEMBER): a multicountry open-label randomised controlled trial.
Mina C Hosseinipour, Gregory P Bisson, Sachiko Miyahara, Xin Sun, Agnes Moses, Paul D Leger

Lancet· March 2016

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Pharmacogenetics of plasma efavirenz exposure in HIV-infected adults and children in South Africa.
Phumla Z Sinxadi, Paul D Leger, Helen M McIlleron, Peter J Smith, Joel A Dave

Br J Clin Pharmacol· July 2015

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Synthetic efforts toward the Lycopodium alkaloids inspires a hydrogen iodide mediated method for the hydroamination and hydroetherification of olefins.
Paul R Leger, Rebecca A Murphy, Eugenia Pushkarskaya, Richmond Sarpong

Chemistry· March 2015

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