Publications by authors named "Paul S Sharp"

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Hemodynamic and neuronal contributions to low-frequency vascular oscillations in a preclinical model of Alzheimer's disease.
Shannon M O'Connor, Runchong Wang, Paul S Sharp, Osman Shabir, Kira Shaw

Neurophotonics· January 2025

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Graphene Oxide Nanoscale Platform Enhances the Anti-Cancer Properties of Bortezomib in Glioblastoma Models.
Paul S Sharp, Maria Stylianou, Luis M Arellano, Juliana C Neves, Alfredo M Gravagnuolo

Adv Healthc Mater· January 2023

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Advanced molecular imaging for the characterisation of complex medicines.
Duygu Yilmaz, Paul S Sharp, Martin J Main, Peter B Simpson

Drug Discov Today· June 2022

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Assessment of neurovascular coupling and cortical spreading depression in mixed mouse models of atherosclerosis and Alzheimer's disease.
Osman Shabir, Ben Pendry, Llywelyn Lee, Beth Eyre, Paul S Sharp

Elife· January 2022

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Neurovascular coupling preserved in a chronic mouse model of Alzheimer's disease: Methodology is critical.
Paul S Sharp, Kamar E Ameen-Ali, Luke Boorman, Sam Harris, Stephen Wharton

J Cereb Blood Flow Metab· November 2020

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The Time Course of Recognition Memory Impairment and Glial Pathology in the hAPP-J20 Mouse Model of Alzheimer's Disease.
Kamar E Ameen-Ali, Julie E Simpson, Stephen B Wharton, Paul R Heath, Paul S Sharp

J Alzheimers Dis· July 2020

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Physiological and Pathological Brain Activation in the Anesthetized Rat Produces Hemodynamic-Dependent Cortical Temperature Increases That Can Confound the BOLD fMRI Signal.
Samuel S Harris, Luke W Boorman, Devashish Das, Aneurin J Kennerley, Paul S Sharp

Front Neurosci· August 2018

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Seizure epicenter depth and translaminar field potential synchrony underlie complex variations in tissue oxygenation during ictal initiation.
Samuel S Harris, Luke W Boorman, Aneurin J Kennerley, Paul S Sharp, Chris Martin

Neuroimage· May 2018

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A novel automated rodent tracker (ART), demonstrated in a mouse model of amyotrophic lateral sclerosis.
Brett M Hewitt, Moi Hoon Yap, Emma F Hodson-Tole, Aneurin J Kennerley, Paul S Sharp

J Neurosci Methods· April 2018

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Site Specific Modification of Adeno-Associated Virus Enables Both Fluorescent Imaging of Viral Particles and Characterization of the Capsid Interactome.
Jayanth S Chandran, Paul S Sharp, Evangelia Karyka, João Miguel da Conceição Aves-Cruzeiro, Ian Coldicott

Sci Rep· November 2017

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Corrigendum: Comparison of stimulus-evoked cerebral hemodynamics in the awake mouse and under a novel anesthetic regime.
Paul S Sharp, Kira Shaw, Luke Boorman, Samuel Harris, Aneurin J Kennerley

Sci Rep· October 2015

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LRP-1-mediated intracellular antibody delivery to the Central Nervous System.
Xiaohe Tian, Sophie Nyberg, Paul S Sharp, Jeppe Madsen, Nooshin Daneshpour

Sci Rep· July 2015

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Comparison of stimulus-evoked cerebral hemodynamics in the awake mouse and under a novel anesthetic regime.
Paul S Sharp, Kira Shaw, Luke Boorman, Samuel Harris, Aneurin J Kennerley

Sci Rep· July 2015

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Abnormalities in whisking behaviour are associated with lesions in brain stem nuclei in a mouse model of amyotrophic lateral sclerosis.
Robyn A Grant, Paul S Sharp, Aneurin J Kennerley, Jason Berwick, Andrew Grierson

Behav Brain Res· February 2014

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Metformin treatment has no beneficial effect in a dose-response survival study in the SOD1(G93A) mouse model of ALS and is harmful in female mice.
Hannah M Kaneb, Paul S Sharp, Nazanin Rahmani-Kondori, Dominic J Wells

PLoS One· January 2012

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Chronic systemic therapy with low-dose morpholino oligomers ameliorates the pathology and normalizes locomotor behavior in mdx mice.
Alberto Malerba, Paul S Sharp, Ian R Graham, Virginia Arechavala-Gomeza, Keith Foster

Mol Ther· February 2011

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Physiological characterization of muscle strength with variable levels of dystrophin restoration in mdx mice following local antisense therapy.
Paul S Sharp, Hema Bye-a-Jee, Dominic J Wells

Mol Ther· January 2011

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Transgenic overexpression of LARGE induces α-dystroglycan hyperglycosylation in skeletal and cardiac muscle.
Martin Brockington, Silvia Torelli, Paul S Sharp, Ke Liu, Sebahattin Cirak

PLoS One· December 2010

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Codon and mRNA sequence optimization of microdystrophin transgenes improves expression and physiological outcome in dystrophic mdx mice following AAV2/8 gene transfer.
Helen Foster, Paul S Sharp, Takis Athanasopoulos, Capucine Trollet, Ian R Graham

Mol Ther· November 2008

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Protective effects of heat shock protein 27 in a model of ALS occur in the early stages of disease progression.
Paul S Sharp, Mohammed T Akbar, Sonia Bouri, Atsushi Senda, Kieran Joshi

Neurobiol Dis· April 2008

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Manipulating transmitter release at the neuromuscular junction of neonatal rats alters the expression of ChAT and GAP-43 in motoneurons.
Paul S Sharp, Joanna Dekkers, James R T Dick, Linda Greensmith

Brain Res Dev Brain Res· December 2003

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