Publications by authors named "Paul Silber"

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An estimate of the number of hepatocyte donors required to provide reasonable estimates of human hepatic clearance from in vitro experiments.
James Byers, Kenneth Bachmann, Heather Eng, Anand Katta, Donald White, Paul Silber

Drug Metab Lett· April 2007

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Structure-activity relationships for halobenzene induced cytotoxicity in rat and human hepatocytes.
Katie Chan, Neil S Jensen, Paul M Silber, Peter J O'Brien

Chem Biol Interact· February 2007

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New cytochrome P450 2D6*56 allele identified by genotype/phenotype analysis of cryopreserved human hepatocytes.
Li Li, Run-Mei Pan, Todd D Porter, Neil S Jensen, Paul Silber

Drug Metab Dispos· August 2006

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Prediction of hepatic clearance using cryopreserved human hepatocytes: a comparison of serum and serum-free incubations.
Nadège Blanchard, Nicola J Hewitt, Paul Silber, Hannah Jones, Philippe Coassolo

J Pharm Pharmacol· May 2006

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Human and animal hepatocytes in vitro with extrapolation in vivo.
Peter J O'Brien, Katie Chan, Paul M Silber

Chem Biol Interact· November 2004

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Catechol-O-methyltransferase low activity genotype (COMTLL) is associated with low levels of COMT protein in human hepatocytes.
Anne E Sullivan Doyle, Julie E Goodman, Paul M Silber, James D Yager

Cancer Lett· October 2004

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Maintenance of liver functions in rat hepatocytes cultured as spheroids in a rotating wall vessel.
Lanika A Brown, Linda M Arterburn, Ana P Miller, Nancy L Cowger, Sonya M Hartley, Paul M Silber

In Vitro Cell Dev Biol Anim· August 2004

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Determination of cytochrome P450 1A2 and cytochrome P450 3A4 induction in cryopreserved human hepatocytes.
Dirk Roymans, Cis Van Looveren, Angelique Leone, J Brandon Parker, Michael McMillian, Paul Silber

Biochem Pharmacol· February 2004

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Differential in vitro hepatotoxicity of troglitazone and rosiglitazone among cryopreserved human hepatocytes from 37 donors.
Scott Lloyd, Michael J Hayden, Yumiko Sakai, Andrew Fackett, Paul M Silber

Chem Biol Interact· November 2002

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Identification of glutathione conjugates of troglitazone in human hepatocytes.
Saileta Prabhu, Andrew Fackett, Scott Lloyd, Holly A McClellan, Chris M Terrell, Paul M Silber

Chem Biol Interact· November 2002

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