Publications by authors named "Philippe Coassolo"

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Follow-up to the pre-validation of a harmonised protocol for assessment of CYP induction responses in freshly isolated and cryopreserved human hepatocytes with respect to culture format, treatment, positive reference inducers and incubation conditions.
Catherine Abadie-Viollon, Hélène Martin, Nadège Blanchard, Dumrongsak Pekthong, Philippe Bachellier, Philippe Coassolo

Toxicol In Vitro· February 2010

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Cryopreserved human hepatocytes in suspension are a convenient high throughput tool for the prediction of metabolic clearance.
Delphine Jouin, Nadège Blanchard, Eliane Alexandre, Frédéric Delobel, Pascale David-Pierson, Philippe Coassolo

Eur J Pharm Biopharm· July 2006

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Prediction of hepatic clearance using cryopreserved human hepatocytes: a comparison of serum and serum-free incubations.
Nadège Blanchard, Nicola J Hewitt, Paul Silber, Hannah Jones, Philippe Coassolo

J Pharm Pharmacol· May 2006

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An evaluation of the utility of physiologically based models of pharmacokinetics in early drug discovery.
Neil Parrott, Nicolas Paquereau, Philippe Coassolo, Thierry Lavé

J Pharm Sci· October 2005

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Impact of serum on clearance predictions obtained from suspensions and primary cultures of rat hepatocytes.
Nadège Blanchard, Lysiane Richert, Brigitte Notter, Frederic Delobel, Pascale David, Philippe Coassolo

Eur J Pharm Sci· October 2004

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