Publications by authors named "Paul Vink"

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Phenotypic pharmacology of novel Complex I inhibitors eliciting tissue repair concurrent to control of inflammation.
Lisa Patel, Fatima Garcia-Raposo, Benjamin Moore, James Wood, Lily Morley, Paul Vink

J Pharmacol Exp Ther· September 2025

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Anti-citrullinated histone monoclonal antibody CIT-013, a dual action therapeutic for neutrophil extracellular trap-associated autoimmune diseases.
Maarten van der Linden, Sangeeta Kumari, Daphne Montizaan, Stephanie van Dalen, Annemarie Kip, Paul Vink

MAbs· December 2023

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Integrated Single-Cell (Phospho-)Protein and RNA Detection Uncovers Phenotypic Characteristics and Active Signal Transduction of Human Antibody-Secreting Cells.
Erik van Buijtenen, Wout Janssen, Paul Vink, Maurice J M Habraken, Laura J A Wingens

Mol Cell Proteomics· February 2023

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Single-cell intracellular epitope and transcript detection reveals signal transduction dynamics.
Francesca Rivello, Erik van Buijtenen, Kinga Matuła, Jessie A G L van Buggenum, Paul Vink

Cell Rep Methods· September 2021

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Functional characterization of the selective pan-allele anti-SIRPα antibody ADU-1805 that blocks the SIRPα-CD47 innate immune checkpoint.
Erik Voets, Marc Paradé, David Lutje Hulsik, Sanne Spijkers, Wout Janssen, Paul Vink

J Immunother Cancer· December 2019

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Molecular mechanism of respiratory syncytial virus fusion inhibitors.
Michael B Battles, Johannes P Langedijk, Polina Furmanova-Hollenstein, Supranee Chaiwatpongsakorn, Heather M Costello, Paul Vink

Nat Chem Biol· February 2016

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Bruton's tyrosine kinase mediates the synergistic signalling between TLR9 and the B cell receptor by regulating calcium and calmodulin.
Elaine F Kenny, Susan R Quinn, Sarah L Doyle, Paul M Vink, Hans van Eenennaam

PLoS One· March 2014

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In vivo knockdown of TAK1 accelerates bone marrow proliferation/differentiation and induces systemic inflammation.
Paul M Vink, Wendy M Smout, Lilian J Driessen-Engels, Alex M de Bruin, Dianne Delsing

PLoS One· September 2013

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Molecular pathway profiling of T lymphocyte signal transduction pathways; Th1 and Th2 genomic fingerprints are defined by TCR and CD28-mediated signaling.
Ruben L Smeets, Wilco W M Fleuren, Xuehui He, Paul M Vink, Frank Wijnands

BMC Immunol· March 2012

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Identification of low abundant secreted proteins and peptides from primary culture supernatants of human T-cells.
Inez Finoulst, Paul Vink, Eric Rovers, Mervin Pieterse, Martijn Pinkse

J Proteomics· December 2011

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Development and characterization of APRIL antagonistic monoclonal antibodies for treatment of B-cell lymphomas.
Marco Guadagnoli, Fiona C Kimberley, Uyen Phan, Katherine Cameron, Paul M Vink

Blood· June 2011

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Therapeutic dosing of an orally active, selective cathepsin S inhibitor suppresses disease in models of autoimmunity.
Mark Baugh, Darcey Black, Paul Westwood, Emma Kinghorn, Kieran McGregor, Paul Vink

J Autoimmun· May 2011

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6-Phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile as cathepsin S inhibitors.
Jiaqiang Cai, Mark Baugh, Darcey Black, Clive Long, D Jonathan Bennett, Paul Vink

Bioorg Med Chem Lett· August 2010

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Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells.
Hans J P M Koenen, Ruben L Smeets, Paul M Vink, Esther van Rijssen, Annemieke M H Boots

Blood· September 2008

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