Publications by authors named "Pavel Moudry"

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The need for speed: drivers and consequences of accelerated replication forks.
Dávid Lukáč, Katarína Chromá, Pavel Moudrý

Commun Biol· November 2025

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DNA polymerase α-primase facilitates PARP inhibitor-induced fork acceleration and protects BRCA1-deficient cells against ssDNA gaps.
Zuzana Machacova, Katarina Chroma, David Lukac, Iva Protivankova, Pavel Moudry

Nat Commun· August 2024

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Emetine blocks DNA replication via proteosynthesis inhibition not by targeting Okazaki fragments.
David Lukac, Zuzana Machacova, Pavel Moudry

Life Sci Alliance· September 2022

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RNA-interference screen for p53 regulators unveils a role of WDR75 in ribosome biogenesis.
Pavel Moudry, Katarina Chroma, Sladana Bursac, Sinisa Volarevic, Jiri Bartek

Cell Death Differ· March 2022

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A drug repurposing strategy for overcoming human multiple myeloma resistance to standard-of-care treatment.
Katarina Chroma, Zdenek Skrott, Jan Gursky, Jaroslav Bacovsky, Pavel Moudry

Cell Death Dis· March 2022

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Perturbation of RNA Polymerase I transcription machinery by ablation of HEATR1 triggers the RPL5/RPL11-MDM2-p53 ribosome biogenesis stress checkpoint pathway in human cells.
Zsofia Turi, Marketa Senkyrikova, Martin Mistrik, Jiri Bartek, Pavel Moudry

Cell Cycle· September 2019

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Impaired ribosome biogenesis: mechanisms and relevance to cancer and aging.
Zsofia Turi, Matthew Lacey, Martin Mistrik, Pavel Moudry

Aging (Albany NY)· April 2019

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High speed of fork progression induces DNA replication stress and genomic instability.
Apolinar Maya-Mendoza, Pavel Moudry, Joanna Maria Merchut-Maya, MyungHee Lee, Robert Strauss

Nature· July 2018

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Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4.
Zdenek Skrott, Martin Mistrik, Klaus Kaae Andersen, Søren Friis, Dusana Majera, Pavel Moudry

Nature· December 2017

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Proteomic profiling reveals DNA damage, nucleolar and ribosomal stress are the main responses to oxaliplatin treatment in cancer cells.
Tomas Ozdian, Dusan Holub, Zuzana Maceckova, Lakshman Varanasi, Gabriela Rylova, Pavel Moudry

J Proteomics· June 2017

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TOPBP1 regulates RAD51 phosphorylation and chromatin loading and determines PARP inhibitor sensitivity.
Pavel Moudry, Kenji Watanabe, Kamila M Wolanin, Jirina Bartkova, Isabel E Wassing

J Cell Biol· February 2016

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Complementary genetic screens identify the E3 ubiquitin ligase CBLC, as a modifier of PARP inhibitor sensitivity.
Jessica Frankum, Pavel Moudry, Rachel Brough, Zdenek Hodny, Alan Ashworth

Oncotarget· May 2015

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Ubiquitin-activating enzyme UBA1 is required for cellular response to DNA damage.
Pavel Moudry, Claudia Lukas, Libor Macurek, Hana Hanzlikova, Zdenek Hodny

Cell Cycle· April 2012

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Autocrine VEGF-VEGFR2-Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth.
Petra Hamerlik, Justin D Lathia, Rikke Rasmussen, Qiulian Wu, Jirina Bartkova, Pavel Moudry

J Exp Med· March 2012

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Bacterial intoxication evokes cellular senescence with persistent DNA damage and cytokine signalling.
Hana Blazkova, Katerina Krejcikova, Pavel Moudry, Teresa Frisan, Zdenek Hodny

J Cell Mol Med· January 2010

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